Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Olga B. Garbuzenko"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10357 (2024)
Our study took an innovative approach by evaluating, in vivo, the efficacy of intranasal (IN) administration of liposomal formulations of donepezil, memantine, and beta-site amyloid precursor protein-cleaving enzyme (BACE-1) siRNA, and their combinat
Externí odkaz:
https://doaj.org/article/a2dbfc7eb5a24c388552bd7233522df3
Publikováno v:
Cancer Biology & Medicine, Vol 11, Iss 1, Pp 44-55 (2014)
Objective Various nanoparticles have been designed and tested in order to select optimal carriers for the inhalation delivery of anticancer drugs to the lungs. Methods The following nanocarriers were studied:micelles, liposomes, mesoporous silica nan
Externí odkaz:
https://doaj.org/article/c00ba8b48a9c4b74b9f78041d9b6506a
Autor:
Sharon R. Pine, Tamara Minko, Jyoti Malhotra, Hatim E. Sabaawy, Olga B. Garbuzenko, Saman Zeeshan, Gina M. Castellano
Supplementary Figure from Inhibition of Mtorc1/2 and DNA-PK via CC-115 Synergizes with Carboplatin and Paclitaxel in Lung Squamous Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b78383535fc0451f72ba47abeb44aa7
https://doi.org/10.1158/1535-7163.22523590.v1
https://doi.org/10.1158/1535-7163.22523590.v1
Autor:
Tamara Minko, Lorna Rodriguez-Rodriguez, Olena R. Taratula, Olga B. Garbuzenko, Oleh Taratula, Vatsal Shah
Purpose: The proposed project is aimed at enhancing the efficiency of epithelial ovarian cancer treatment and reducing adverse side effects of chemotherapy using nanotechnology. Overexpression of the CD44 membrane receptor results in tumor initiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7711c9349676769c2a60dbc51d5aad56
https://doi.org/10.1158/1078-0432.c.6522282.v1
https://doi.org/10.1158/1078-0432.c.6522282.v1
Autor:
Tamara Minko, Lorna Rodriguez-Rodriguez, Olena R. Taratula, Olga B. Garbuzenko, Oleh Taratula, Vatsal Shah
PDF file - 105K, The supplementary data file contains detailed descriptions of the following methods: MALDI TOF Mass Spectroscopy; Atomic Force Microscopy; Particle Size and Charge; Stability of the Complexes in Serum; Cellular Internalization; Cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d04ab6a331b5243db29012f4f704e04
https://doi.org/10.1158/1078-0432.22451760.v1
https://doi.org/10.1158/1078-0432.22451760.v1
Publikováno v:
Theranostics
Non-Small Cell Lung Carcinoma (NSCLC), is the most common type of lung cancer (more than 80% of all cases). Small molecule Tyrosine Kinase (TK) Inhibitors acting on the Epidermal Growth Factor Receptors (EGFRs) are standard therapies for patients wit
Publikováno v:
J Control Release
Chemotherapy-induced peripheral neuropathy (CIPN) is a major adverse effect of paclitaxel. Several liposome-based products have been approved and demonstrated superior efficacy and safety profiles for other drugs. The first objective of this work was
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society
Cystic fibrosis (CF), a most deadly genetic disorder, is caused by mutations of CF transmembrane receptor (CFTR) - a chloride channel present at the surface of epithelial cells. In general, two steps have to be involved in treatment of the disease: c
Autor:
Joseph R. Bertino, Gulam M. Rather, Michael Anyanwu, Tamara Minko, Olga B. Garbuzenko, Zoltan Szekely
Publikováno v:
Cancers
Volume 13
Issue 5
Cancers, Vol 13, Iss 972, p 972 (2021)
Volume 13
Issue 5
Cancers, Vol 13, Iss 972, p 972 (2021)
Simple Summary The E2F family of transcription factors are essential for cell proliferation, differentiation, and DNA repair. They are commonly overexpressed or dysregulated in cancer as a consequence of inactivation or mutations in the retinoblastom
Autor:
Nitu Bansal, Tazeem Shaik, Debabrata Banerjee, John E. Kerrigan, Zoltan Szekely, Joseph R. Bertino, Kathleen W. Scotto, Tamara Minko, Gulam M. Rather, Olga B. Garbuzenko, Emine Ercikan Abali
Publikováno v:
Oncotarget
E2F1-3a overexpression due to amplification or to mutation or loss of the retinoblastoma gene, induces genes involved in DNA synthesis and leads to abnormal cellular proliferation, tumor growth, and invasion. Therefore, inhibiting the overexpression