Zobrazeno 1 - 2
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pro vyhledávání: '"Olga Aronov"'
Publikováno v:
Bioconjugate Chemistry. 14:563-574
Like most low molecular weight drugs, carboplatin has a short blood circulation time, which reduces tumor uptake and intracellular DNA binding. Drugs conjugated to PEG carriers benefit from prolonged blood circulation, but suffer from reduced cell pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bfa359cab28091a75cf2470ff55a17
https://doi.org/10.1021/bc025642l
https://doi.org/10.1021/bc025642l
Autor:
Miguel A. Fuertes, Alberto Gabizon, Dan Gibson, Aviva T. Horowitz, José M. Pérez, Olga Aronov
Publikováno v:
Bioconjugate chemistry. 15(4)
Carboplatin is a low-molecular-weight anticancer drug that acts by binding to the nuclear DNA of cells. Thus, efficient delivery of the platinum drugs to the nucleus of the cancer cells may enhance the cytotoxicity of the drug. Efficient drug deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cad9f76bc70e740d1f83e1c912c08f
https://pubmed.ncbi.nlm.nih.gov/15264869
https://pubmed.ncbi.nlm.nih.gov/15264869