Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Olga Aminova"'
Autor:
Matija Snuderl, Kasthuri Kannan, Elke Pfaff, Shiyang Wang, James M. Stafford, Jonathan Serrano, Adriana Heguy, Karina Ray, Arline Faustin, Olga Aminova, Igor Dolgalev, Stacie L. Stapleton, David Zagzag, Luis Chiriboga, Sharon L. Gardner, Jeffrey H. Wisoff, John G. Golfinos, David Capper, Volker Hovestadt, Marc K. Rosenblum, Dimitris G. Placantonakis, Sarah E. LeBoeuf, Thales Y. Papagiannakopoulos, Lukas Chavez, Sama Ahsan, Charles G. Eberhart, Stefan M. Pfister, David T. W. Jones, Matthias A. Karajannis
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Pineoblastoma is a highly aggressive and rare childhood brain cancer, and the genetic drivers of sporadic pineoblastoma are unknown. Here, the authors genomically interrogated pediatric and adult pineoblastomas and found novel variants including recu
Externí odkaz:
https://doaj.org/article/ead93584496f48eaacd71d7cac4d1501
Autor:
Omar Abdel-Wahab, Tanja A. Gruber, Neal Rosen, Jean-Francois Emile, Ahmet Dogan, Zahir Amoura, Christopher Y. Park, Barry S. Taylor, Filip Janku, José Baselga, David M. Hyman, David B. Solit, Jean Donadieu, Sebastien Héritier, Jared Block, Omotayo Fasan, Samuel R. Briggs, Siraj M. Ali, Jeffrey S. Ross, Vincent A. Miller, Philip J. Stephens, William A. Gahl, Mario Lacouture, Juvianee Estrada-Veras, David W. Ellison, James D. Dalton, Chezi Ganzel, Joy Nakitandwe, Paul Zappile, Adriana Heguy, Olga Aminova, Igor Dolgalev, Brooke Sylvester, Michael P. Walsh, Patrick Campbell, Jean-Baptiste Micol, Yijun Gao, Stanley Chun-Wei Lee, Fleur Cohen-Aubart, Eunhee Kim, John Choi, Zhaoming Wang, Sameer A. Parikh, Jing Ma, Zhan Yao, Julien Haroche, Benjamin H. Durham, Eli L. Diamond
Supplementary Figure 1. Somatic mutations detected in histiocytic neoplasms. Supplementary Figure 2. Frequencies of known activating kinase mutations in histiocytic neoplasms. Supplementary Figure 3. ARAF mutations and variants of unknown significanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0075033853c222afd5d85bcdeb5cc286
https://doi.org/10.1158/2159-8290.22530029.v1
https://doi.org/10.1158/2159-8290.22530029.v1
Autor:
Volker Hovestadt, Sama Ahsan, Dimitris G. Placantonakis, Thales Papagiannakopoulos, Sharon Gardner, Arline Faustin, Kasthuri Kannan, Charles G. Eberhart, Stefan M. Pfister, Olga Aminova, Shiyang Wang, James M. Stafford, Adriana Heguy, Jeffrey H. Wisoff, Luis Chiriboga, Marc K. Rosenblum, Karina Ray, Jonathan Serrano, Elke Pfaff, Igor Dolgalev, David Zagzag, Matthias A. Karajannis, John G. Golfinos, Stacie Stapleton, David Capper, Matija Snuderl, Sarah E. LeBoeuf, David T.W. Jones, Lukas Chavez
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Pineoblastoma is a rare and highly aggressive brain cancer of childhood, histologically belonging to the spectrum of primitive neuroectodermal tumors. Patients with germline mutations in DICER1, a ribonuclease involved in microRNA processing, have in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a64bf33a6b9c6c1f0eb25c65e9ceef0
https://doi.org/10.1038/s41467-018-05029-3
https://doi.org/10.1038/s41467-018-05029-3
Autor:
Shiyang Wang, James M. Stafford, Charles G. Eberhart, Sharon Gardner, Dimitris G. Placantonakis, Volker Hovestadt, David T.W. Jones, Lukas Chavez, Adriana Heguy, Stacie Stapleton, Jonathan Serrano, Matthias A. Karajannis, Sarah E. LeBoeuf, Matija Snuderl, Luis Chiriboga, Olga Aminova, Karina Ray, Marc K. Rosenblum, David Capper, Sama Ahsan, Kasthuri Kannan, Jeffrey H. Wisoff, Elke Pfaff, Igor Dolgalev, Thales Papagiannakopoulos, John G. Golfinos, Arline Faustin, Stefan M. Pfister, David Zagzag
BACKGROUND: Pineoblastoma is a rare and highly aggressive brain cancer of childhood, histologically belonging to the spectrum of primitive neuroectodermal tumors. Patients with germline mutations in DICER1, a ribonuclease involved in microRNA process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e93b59df9c372fc8673efa1ea4af05e
https://europepmc.org/articles/PMC6012258/
https://europepmc.org/articles/PMC6012258/
Autor:
Elisabeth Paietta, Hugo Fernandez, Jay P. Patel, Robert E. Gallagher, Igor Dolgalev, Kety Huberman, Sabrena Thomas, Rodney R. Higgins, Janice Cheng, Marcel R.M. van den Brink, Pieter Van Vlierberghe, Ari Melnick, Rhett P. Ketterling, Adolfo A. Ferrando, Maria E. Figueroa, Ross L. Levine, Adriana Heguy, Janis Racevskis, Omar Abdel-Wahab, Zhuoxin Sun, Jacob M. Rowe, Martin S. Tallman, Hillard M. Lazarus, Selina M. Luger, Athena M. Cherry, Olga Aminova, Nicholas D. Socci, Mithat Gonen, Mark R. Litzow, Agnes Viale, Gail H. Vance
Publikováno v:
New England Journal of Medicine. 366:1079-1089
Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. The prognostic value of recently identified somatic mutations has not been systematically evaluated in a phase 3 trial of treatment for AML.We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7dcf0cb5d31066854ae1fd2964a65f
https://doi.org/10.1056/nejmoa1112304
https://doi.org/10.1056/nejmoa1112304
Publikováno v:
Biochemistry. 47:12670-12679
Herein, we report the RNA hairpin loops from a 6-nucleotide hairpin library that bind 6′-acylated kanamycin A (1) and 6′-acylated neamine (2) identified by 2-Dimensional Combinatorial Screening (2DCS). Hairpins selected to bind 1 have Kd's rangin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eced83b7302eeb15cc0c19b7f123834f
https://doi.org/10.1021/bi8012615
https://doi.org/10.1021/bi8012615
Publikováno v:
ACS Chemical Biology. 2:745-754
Herein, we report the development of a microarray platform to select RNA motif-ligand interactions that allows simultaneous screening of both RNA and chemical space. We used this platform to identify the RNA internal loops that bind 6'- N-5-hexynoate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65cac44b8151bd8a73a8a0490d83d88
https://doi.org/10.1021/cb700174r
https://doi.org/10.1021/cb700174r
Autor:
Jeffrey H. Wisoff, Matija Snuderl, Matthias A. Karajannis, Sharon Gardner, Sama Ahsan, David T.W. Jones, Igor Dolgalev, Adriana Heguy, Jeffrey C. Allen, Arline Faustin, Olga Aminova, David Zagzag, Stefan M. Pfister, Kasthuri Kannan, Volker Hovestadt, Charles G. Eberhart, David Capper
INTRODUCTION: Pineoblastoma (PB) is one of the rarest and most aggressive brain tumors of childhood. PB is considered a "primitive neuroectodermal tumor" (PNET) based on histology, and commonly treated using treatment protocols developed for medullob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e2156e82a9e7c3a3a57608e2c0bc1e
https://europepmc.org/articles/PMC4638812/
https://europepmc.org/articles/PMC4638812/
Autor:
Jared Block, Julien Haroche, Neal Rosen, Paul Zappile, Adriana Heguy, Yijun Gao, Zhan Yao, Juvianee Estrada-Veras, Ahmet Dogan, William A. Gahl, Jean-François Emile, Eli L. Diamond, Zhaoming Wang, Jeffrey S. Ross, Filip Janku, Fleur Cohen-Aubart, Michael P. Walsh, Jean Donadieu, Barry S. Taylor, Jean Baptiste Micol, Stanley Chun-Wei Lee, Omotayo Fasan, Chezi Ganzel, Siraj M. Ali, Jing Ma, Brooke E. Sylvester, Christopher Y. Park, José Baselga, Vincent A. Miller, Eunhee Kim, Igor Dolgalev, David W. Ellison, Benjamin H. Durham, James Dalton, Sébastien Héritier, Olga Aminova, Patrick Campbell, Joy Nakitandwe, Tanja A. Gruber, Samuel Briggs, David M. Hyman, Philip J. Stephens, Omar Abdel-Wahab, Zahir Amoura, Sameer A. Parikh, Mario E. Lacouture, David B. Solit, John K. Choi
Publikováno v:
Cancer discovery. 6(2)
Histiocytic neoplasms are clonal, hematopoietic disorders characterized by an accumulation of abnormal, monocyte-derived dendritic cells or macrophages in Langerhans cell histiocytosis (LCH) and non-Langerhans cell histiocytosis (non-LCH), respective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523bb39a15fa6dd0b9174117b1268d0c
https://pubmed.ncbi.nlm.nih.gov/26566875
https://pubmed.ncbi.nlm.nih.gov/26566875
Autor:
Adriana Heguy, Matthias A. Karajannis, Matija Snuderl, David Capper, David Zagzag, Igor Dolgalev, Jeffrey C. Allen, Sama Ahsan, Arline Faustin, Sharon Gardner, Jeffrey H. Wisoff, Volker Hovestadt, Stefan M. Pfister, David T.W. Jones, Kasthuri Kannan, Charles G. Eberhart, Olga Aminova
INTRODUCTION: Pineoblastoma (PB) is one of the rarest and most aggressive brain tumors of childhood. PB is considered a “primitive neuroectodermal tumor” (PNET) based on histology, and commonly treated using treatment protocols developed for medu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10528fc837fcf896b27f4f72335cac0e
https://europepmc.org/articles/PMC4483029/
https://europepmc.org/articles/PMC4483029/