Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Olga, Plotnikova"'
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
MicroRNAs play a key role in the regulation of gene expression. A majority of microRNA–mRNA interactions remain unidentified. Despite extensive research, our ability to predict human microRNA-mRNA interactions using computational algorithms remains
Externí odkaz:
https://doaj.org/article/7a419aaa188a4d7581961cca59c0446b
Autor:
Xiaodi Yu, Olga Plotnikova, Paul D Bonin, Timothy A Subashi, Thomas J McLellan, Darren Dumlao, Ye Che, Yin Yao Dong, Elisabeth P Carpenter, Graham M West, Xiayang Qiu, Jeffrey S Culp, Seungil Han
Publikováno v:
eLife, Vol 8 (2019)
Alanine-serine-cysteine transporter 2 (ASCT2, SLC1A5) is the primary transporter of glutamine in cancer cells and regulates the mTORC1 signaling pathway. The SLC1A5 function involves finely tuned orchestration of two domain movements that include the
Externí odkaz:
https://doaj.org/article/a33c8724acd14c1bb4ac82ee1b35322f
Autor:
Olga Plotnikova
The article formulates the main aspects of understanding power as a social phenomenon. The philosophy of Power is a complex multi–faceted research project. Being a social phenomenon, power arises as a result of relations between people, and all mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a96a8c2c3e94e333e55911c20ffd6ac
Autor:
Justin Hall, Amy Brault, Fabien Vincent, Shawn Weng, Hong Wang, Darren Dumlao, Ann Aulabaugh, Dikran Aivazian, Dana Castro, Ming Chen, Jeffrey Culp, Ken Dower, Joseph Gardner, Steven Hawrylik, Douglas Golenbock, David Hepworth, Mark Horn, Lyn Jones, Peter Jones, Eicke Latz, Jing Li, Lih-Ling Lin, Wen Lin, David Lin, Frank Lovering, Nootaree Niljanskul, Ryan Nistler, Betsy Pierce, Olga Plotnikova, Daniel Schmitt, Suman Shanker, James Smith, William Snyder, Timothy Subashi, John Trujillo, Edyta Tyminski, Guoxing Wang, Jimson Wong, Bruce Lefker, Leslie Dakin, Karen Leach
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184843 (2017)
Cyclic GMP-AMP synthase (cGAS) initiates the innate immune system in response to cytosolic dsDNA. After binding and activation from dsDNA, cGAS uses ATP and GTP to synthesize 2', 3' -cGAMP (cGAMP), a cyclic dinucleotide second messenger with mixed 2'
Externí odkaz:
https://doaj.org/article/6bb0be80b7c34a3aa6c36d9154eb7079
Publikováno v:
Computational Biophysics and Nanobiophotonics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86e5ce47d3cad401f63f2dbf5e5adc8
https://doi.org/10.1117/12.2626337
https://doi.org/10.1117/12.2626337
Autor:
Ariamala Gopalsamy, Ann E. Aulabaugh, Amey Barakat, Kevin C. Beaumont, Shawn Cabral, Daniel P. Canterbury, Agustin Casimiro-Garcia, Jeanne S. Chang, Ming Z. Chen, Chulho Choi, Robert L. Dow, Olugbeminiyi O. Fadeyi, Xidong Feng, Scott P. France, Roger M. Howard, Jay M. Janz, Jayasankar Jasti, Reema Jasuja, Lyn H. Jones, Amanda King-Ahmad, Kelly M. Knee, Jeffrey T. Kohrt, Chris Limberakis, Spiros Liras, Carlos A. Martinez, Kim F. McClure, Arjun Narayanan, Jatin Narula, Jonathan J. Novak, Thomas N. O’Connell, Mihir D. Parikh, David W. Piotrowski, Olga Plotnikova, Ralph P. Robinson, Parag V. Sahasrabudhe, Raman Sharma, Benjamin A. Thuma, Dipy Vasa, Liuqing Wei, A. Zane Wenzel, Jane M. Withka, Jun Xiao, Hatice G. Yayla
Publikováno v:
Journal of Medicinal Chemistry. 64:326-342
Sickle cell disease (SCD) is a genetic disorder caused by a single point mutation (β6 Glu → Val) on the β-chain of adult hemoglobin (HbA) that results in sickled hemoglobin (HbS). In the deoxygenated state, polymerization of HbS leads to sickling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fb3aa72d831f7f375af97473787b3a
https://doi.org/10.1021/acs.jmedchem.0c01518
https://doi.org/10.1021/acs.jmedchem.0c01518
Autor:
Samantha E. Greasley, Stephen Noell, Olga Plotnikova, RoseAnn Ferre, Wei Liu, Ben Bolanos, Kimberly Fennell, Jennifer Nicki, Tim Craig, Yuao Zhu, Al E. Stewart, Claire M. Steppan
Publikováno v:
Journal of Biological Chemistry. 298:101972
The COVID-19 pandemic continues to be a public health threat with emerging variants of SARS-CoV-2. Nirmatrelvir (PF-07321332) is a reversible, covalent inhibitor targeting the main protease (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea1b482d6a390935cf29ac08a2b3881
https://doi.org/10.1016/j.jbc.2022.101972
https://doi.org/10.1016/j.jbc.2022.101972
Autor:
Shreya Agarwal, James D. Phelan, George E. Wright, Stefania Pittaluga, Grace Smith, Chen Yao, Moyi Li, Olga Plotnikova, Katsuyoshi Takata, Nikita Kotlov, Jagan R. Muppidi, Maryam Yamadi, Krystle Nomie, Raud Razzaghi, John J. O'Shea, Da-Wei Huang, David Scott
Publikováno v:
The Journal of Experimental Medicine
The role of Fas in germinal center (GC) homeostasis is controversial. Razzaghi et al. show that Fas is a strong cell-intrinsic regulator of the GC and that its loss defines an aggressive subtype of GC-derived lymphoma.
Fas is highly expressed on
Fas is highly expressed on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac09581e0259fd0cd149fc15447573be
https://doi.org/10.1084/jem.20201173
https://doi.org/10.1084/jem.20201173
Autor:
Prashant V. Thakkar, Sandipto Sarkar, Navjot Kaur, Olga Plotnikova, Olivier Elemento, Dina Elmonshed, Aleksander Bagaev, Andrew H. Ko, Doron Betel, Meredith E. Pittman, Peter C. Enzinger, Nikita Kotlov, Bhavneet Bhinder, Philip A. Philip, Heinz-Josef Lenz, Kyle Cleveland, Manish A. Shah, Chao Zhang, Allyson J. Ocean, Paraskevi Giannakakou, Yao Lu, Paul J. Christos, Felix Frenkel, Giuseppe Galletti, Jeremy S. Kortmansky
Publikováno v:
Clin Cancer Res
Purpose:We examined cabazitaxel, a novel next-generation taxoid, in patients with metastatic gastric cancer in a multicenter phase II study.Patients and Methods:Patients who have progressed on one or more prior therapies for locally advanced, unresec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8e198339b605bbbf676ab323992a58
https://europepmc.org/articles/PMC8209413/
https://europepmc.org/articles/PMC8209413/
Autor:
Alexandr Reznik, O. N. Reznik, Andrey Skvortsov, Ancha Baranova, Olga Plotnikova, Mikhail Skoblov
Publikováno v:
BioMed Research International, Vol 2018 (2018)
BioMed Research International
BioMed Research International
Utilization of kidneys from extended criteria donors leads to an increase in average warm ischemia time (WIT), which is associated with larger degrees of ischemia-reperfusion injury (IRI). Kidney resuscitation by extracorporeal perfusion in situ allo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a05227c86269eddeb3a312044802b7
https://doi.org/10.1155/2018/5717913
https://doi.org/10.1155/2018/5717913