Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Olga, Mazuryk"'
Publikováno v:
Inorganics, Vol 11, Iss 10, p 391 (2023)
Two copper(II) complexes (Cu-L1, Cu-L2) derived from 2,3-substituted quinazolinone Schiff base ligands (L1, L2) were prepared to examine their anticancer activity. Compounds were characterized using various spectroscopic methods (FTIR, NMR, UV-vis) a
Externí odkaz:
https://doaj.org/article/042135ea58f046078a79fb036fc163fc
Autor:
Ilona Gurgul, Olga Mazuryk, Kamila Stachyra, Rafał Olszanecki, Małgorzata Lekka, Michał Łomzik, Franck Suzenet, Philippe C. Gros, Małgorzata Brindell
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7708 (2022)
The use of polypyridyl Ru complexes to inhibit metastasis is a novel approach, and recent studies have shown promising results. We have reported recently that Ru (II) complexes gathering two 4,7-diphenyl-1,10-phenanthroline (dip) ligands and the one
Externí odkaz:
https://doaj.org/article/d7466853ac60416ea15bc5a6172bcbb5
Publikováno v:
Cancers, Vol 14, Iss 11, p 2686 (2022)
Hypoxia is one of the hallmarks of the tumor microenvironment and can be used in the design of targeted therapies. Cellular adaptation to hypoxic stress is regulated by hypoxia-inducible factor 1 (HIF-1). Hypoxia is responsible for the modification o
Externí odkaz:
https://doaj.org/article/396c447244c1490497517a7d02b5ceaa
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Air pollution is associated with numerous negative effects on human health. The toxicity of organic components of air pollution is well-recognized, while the impact of their inorganic counterparts in the overall toxicity is still a matter of various
Externí odkaz:
https://doaj.org/article/031cdf208d184249a156b1b0125fb91d
Autor:
Przemysław Gajda-Morszewski, Ilona Gurgul, Ewelina Janczy-Cempa, Olga Mazuryk, Michał Łomzik, Małgorzata Brindell
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1014 (2021)
Primary tumor targeting is the dominant approach in drug development, while metastasis is the leading cause of cancer death. Therefore, in addition to the cytotoxic activity of a series of Ru(II) polypyridyl complexes of the type [Ru(dip)2L]2+ (dip:
Externí odkaz:
https://doaj.org/article/212dc95d9cfe49ba85d3712610a12e35
Autor:
Ilona Gurgul, Ewelina Janczy-Cempa, Olga Mazuryk, Małgorzata Lekka, Michał Łomzik, Franck Suzenet, Philippe C. Gros, Małgorzata Brindell
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 2022, 65 (15), pp.10459-10470. ⟨10.1021/acs.jmedchem.2c00580⟩
Journal of Medicinal Chemistry, 2022, 65 (15), pp.10459-10470. ⟨10.1021/acs.jmedchem.2c00580⟩
International audience; The effect of polypyridyl Ru(II) complexes on the ability of cancer cells to migrate and invade, two features important in the formation of metastases, is evaluated. In vitro studies are carried out on breast cancer cell lines
Autor:
Bernadeta Nowak, Anna Wądołek, Olga Mazuryk, Anna Poznańska, Katarzyna Majzner, Grzegorz Majka, Maria Oszajca, Małgorzata Barańska, Grażyna Stochel, Janusz Marcinkiewicz
Publikováno v:
Archivum Immunologiae et Therapiae Experimentalis. 71
Exposure to air particulate matter (PM) is linked to the blood oxidative stress and systemic inflammation. The aim of this study was to elucidate whether oxidative PM modification of ovalbumin (OVA), the major antioxidant serum protein, may alter its
Autor:
Chezhiyan, Sumithaa, Tamilvelan, Manjunathan, Olga, Mazuryk, Silda, Peters, Renjith S, Pillai, Malgorzata, Brindell, Pushparathinam, Gopinath, Mani, Ganeshpandian
Publikováno v:
ACS applied bio materials. 5(7)
The organometallic compounds are prospective candidates in the row of developing metallochemotherapeutics with the aim of overcoming the limitations of platinum drugs. In order to explore the anticancer properties of organometallic compounds with the
Autor:
Ilona Gurgul, Olga Mazuryk, Dorota Rutkowska-Zbik, Michał Łomzik, Aneta Krasowska, Piotr Pietrzyk, Grażyna Stochel, Małgorzata Brindell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a557413e727f9da03a04bef86b8abc
https://ruj.uj.edu.pl/xmlui/handle/item/300039
https://ruj.uj.edu.pl/xmlui/handle/item/300039
Autor:
Olga Mazuryk, Ilona Gurgul, Michał Łomzik, Przemysław Gajda-Morszewski, Małgorzata Brindell, Ewelina Janczy-Cempa
Publikováno v:
Pharmaceuticals
Volume 14
Issue 10
Pharmaceuticals, Vol 14, Iss 1014, p 1014 (2021)
Volume 14
Issue 10
Pharmaceuticals, Vol 14, Iss 1014, p 1014 (2021)
Primary tumor targeting is the dominant approach in drug development, while metastasis is the leading cause of cancer death. Therefore, in addition to the cytotoxic activity of a series of Ru(II) polypyridyl complexes of the type [Ru(dip)2L]2+ (dip: