Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Olga, Hartwig"'
Autor:
Egle Kvedaraite, Magda Lourda, Natalia Mouratidou, Tim Düking, Avinash Padhi, Kirsten Moll, Paulo Czarnewski, Indranil Sinha, Ioanna Xagoraris, Efthymia Kokkinou, Anastasios Damdimopoulos, Whitney Weigel, Olga Hartwig, Telma E. Santos, Tea Soini, Aline Van Acker, Nelly Rahkonen, Malin Flodström Tullberg, Emma Ringqvist, Marcus Buggert, Carl Jorns, Ulrik Lindforss, Caroline Nordenvall, Christopher T. Stamper, David Unnersjö-Jess, Mira Akber, Ruta Nadisauskaite, Jessica Jansson, Niels Vandamme, Chiara Sorini, Marijke Elise Grundeken, Helena Rolandsdotter, George Rassidakis, Eduardo J. Villablanca, Maja Ideström, Stefan Eulitz, Henrik Arnell, Jenny Mjösberg, Jan-Inge Henter, Mattias Svensson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Stromal cells support epithelial cell and immune cell homeostasis and play an important role in inflammatory bowel disease (IBD) pathogenesis. Here, we quantify the stromal response to inflammation in pediatric IBD and reveal subset-specific
Externí odkaz:
https://doaj.org/article/4dc18c7a87ab47da922abb5a03ceaf68
Autor:
Kirsten Hildebrandt, Dieter Kolb, Christine Klöppel, Petra Kaspar, Fabienne Wittling, Olga Hartwig, Jannic Federspiel, India Findji, Uwe Walldorf
Publikováno v:
Hereditas, Vol 159, Iss 1, Pp 1-23 (2022)
Abstract Background The homeobox gene homeobrain (hbn) is located in the 57B region together with two other homeobox genes, Drosophila Retinal homeobox (DRx) and orthopedia (otp). All three genes encode transcription factors with important functions
Externí odkaz:
https://doaj.org/article/97974f1fa73e40ff89ee01e7ffe21b69
Proteoid biodynamers for safe mRNA transfection via pH-responsive nanorods enabling endosomal escape
Autor:
Sangeun Lee, Sarah Nasr, Sari Rasheed, Yun Liu, Olga Hartwig, Cansu Kaya, Annette Boese, Marcus Koch, Jennifer Herrmann, Rolf Müller, Brigitta Loretz, Eric Buhler, Anna K.H. Hirsch, Claus-Michael Lehr
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 353
The recent success of mRNA vaccines using lipid-based vectors highlights the importance of strategies for nucleotide delivery under the pandemic situation. Although current mRNA delivery is focused on lipid-based vectors, still they need to be optimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046a3410d04110a495d78b1cd1ca4715
https://pubmed.ncbi.nlm.nih.gov/36521693
https://pubmed.ncbi.nlm.nih.gov/36521693
Autor:
Eva C. Arrua, Olga Hartwig, Brigitta Loretz, Héctor Goicoechea, Xabier Murgia, Claus-Michael Lehr, Claudio J. Salomon
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 217
Chagas disease is a neglected tropical disease affecting the American continent and also some regions of Europe. Benznidazole, approved by FDA, is a drug of choice but its poor aqueous solubility may lead to a low bioavailability and efficacy. Theref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85554e9e973723683fbff929c2713fe
https://pubmed.ncbi.nlm.nih.gov/35816885
https://pubmed.ncbi.nlm.nih.gov/35816885
Autor:
Olga Hartwig, Brigitta Loretz, Adrien Nougarede, Dorothée Jary, Eric Sulpice, Xavier Gidrol, Fabrice Navarro, Claus-Michael Lehr
Publikováno v:
Journal of Controlled Release
Journal of Controlled Release, 2022, 345, pp.646-660. ⟨10.1016/j.jconrel.2022.03.037⟩
Journal of Controlled Release, 2022, 345, pp.646-660. ⟨10.1016/j.jconrel.2022.03.037⟩
Complex in vitro models of human immune cells and intestinal mucosa may have a translation-assisting role in the assessment of anti-inflammatory compounds. Chronic inflammation of the gastrointestinal tract is a hallmark of inflammatory bowel disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8eac395b05215f8962709f4a8f6c9c
https://pubmed.ncbi.nlm.nih.gov/35339579
https://pubmed.ncbi.nlm.nih.gov/35339579
Autor:
Eva C, Arrua, Olga, Hartwig, Duy-Khiet, Ho, Brigitta, Loretz, Xabier, Murgia, Claudio J, Salomon, Claus-Michael, Lehr
Publikováno v:
Pharmaceutical research. 38(6)
The aim of this work was to formulate and characterize surfactant-free glibenclamide nanoparticles using Eudragit RLPO and polyethylene glycol as sole stabilizer.Glibenclamide nanoparticles were obtained by nanoprecipitation and evaluated in terms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a7b6f4d85b591d1b9189fbf11eb29942
https://pubmed.ncbi.nlm.nih.gov/34002324
https://pubmed.ncbi.nlm.nih.gov/34002324
Autor:
Xabier Murgia, Olga Hartwig, Claudio J. Salomon, Brigitta Loretz, Claus-Michael Lehr, Duy-Khiet Ho, Eva Carolina Arrua
Publikováno v:
Pharmaceutical Research
The aim of this work was to formulate and characterize surfactant-free glibenclamide nanoparticles using Eudragit RLPO and polyethylene glycol as sole stabilizer. Glibenclamide nanoparticles were obtained by nanoprecipitation and evaluated in terms o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ccc772fca82a1f03ebe7dccab7c713
Autor:
Karim S. Shalaby, Maryam A. Shetab Boushehri, Brigitta Loretz, Alf Lamprecht, Claus-Michael Lehr, Olga Hartwig
Publikováno v:
Advanced Drug Delivery Reviews. 175:113828
Current treatment strategies for inflammatory bowel disease (IBD) seek to alleviate the undesirable symptoms of the disorder. Despite the higher specificity of newer generation therapeutics, e.g. monoclonal antibodies, adverse effects still arise fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5306b77f25301bc7e8c1f08cd12b3655
https://doi.org/10.1016/j.addr.2021.113828
https://doi.org/10.1016/j.addr.2021.113828
Autor:
Alexander Biehl, Benedikt Huck, Xabier Murgia, Konrad Schwarzkopf, Christian Wagner, Brigitta Loretz, Claus-Michael Lehr, Olga Hartwig
Publikováno v:
Biomacromolecules
Mucus is a complex hydrogel that acts as a protective barrier in various parts of the human body. Both composition and structural properties play a crucial role in maintaining barrier properties while dictating diffusion of molecules and (nano)materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7927a2fbcddec2b272366cb43f6440
https://pubmed.ncbi.nlm.nih.gov/31419118
https://pubmed.ncbi.nlm.nih.gov/31419118
Publikováno v:
Advanced drug delivery reviews
A layer of mucus covers the surface of all wet epithelia throughout the human body. Mucus is a hydrogel mainly composed of water, mucins (glycoproteins), DNA, proteins, lipids, and cell debris. This complex composition yields a tenacious viscoelastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a57f4f4b2c1b0fbc8e17f509877e53a
https://hdl.handle.net/10033/621764
https://hdl.handle.net/10033/621764
