Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Olga, Švecová"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Sildenafil (Viagra), the first approved and widely used oral drug for the treatment of erectile dysfunction, was occasionally associated with life-threatening ventricular arrhythmias in patients. Since inward rectifier potassium current (IK1) may con
Externí odkaz:
https://doaj.org/article/b1861e74910d4693ba4e49759f037afe
Autor:
Iva Synková, Markéta Bébarová, Irena Andršová, Larisa Chmelikova, Olga Švecová, Jan Hošek, Michal Pásek, Pavel Vít, Iveta Valášková, Renata Gaillyová, Rostislav Navrátil, Tomáš Novotný
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The variant c.926C > T (p.T309I) in KCNQ1 gene was identified in 10 putatively unrelated Czech families with long QT syndrome (LQTS). Mutation carriers (24 heterozygous individuals) were more symptomatic compared to their non-affected relati
Externí odkaz:
https://doaj.org/article/78136d3d7b394d9da2840cbe7a5654c8
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The transverse-axial tubular system (t-tubules) plays an essential role in excitation-contraction coupling in cardiomyocytes. Its remodelling is associated with various cardiac diseases. Numerous attempts were made to analyse characteristics essentia
Externí odkaz:
https://doaj.org/article/668d4176bc62458f988676adfa93ae6e
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Sildenafil (Viagra) is a vasodilator mainly used in the treatment of erectile dysfunction. Atrial or ventricular fibrillation may rarely occur as a side effect during sildenafil therapy. Although changes in inward rectifier potassium currents includi
Externí odkaz:
https://doaj.org/article/bb2d4d2babf14c94a80ed28ee439110f
Autor:
Iva Synková, Markéta Bébarová, Irena Andršová, Larisa Chmelikova, Olga Švecová, Jan Hošek, Michal Pásek, Pavel Vít, Iveta Valášková, Renata Gaillyová, Rostislav Navrátil, Tomáš Novotný
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-3 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/7c77c1c50fb8444f9500e1f8d6f47bde
Publikováno v:
Frontiers in physiology. 13
The transverse-axial tubular system (t-tubules) plays an essential role in excitation-contraction coupling in cardiomyocytes. Its remodelling is associated with various cardiac diseases. Numerous attempts were made to analyse characteristics essentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58aafc69822abc4b5e5af36abe0db143
https://pubmed.ncbi.nlm.nih.gov/35620609
https://pubmed.ncbi.nlm.nih.gov/35620609
Publikováno v:
Frontiers in pharmacology. 13
Sildenafil (Viagra) is a vasodilator mainly used in the treatment of erectile dysfunction. Atrial or ventricular fibrillation may rarely occur as a side effect during sildenafil therapy. Although changes in inward rectifier potassium currents includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::196619c40c6c2112e231e0f3eb6e3690
https://pubmed.ncbi.nlm.nih.gov/35548367
https://pubmed.ncbi.nlm.nih.gov/35548367
The tubular system of cardiomyocytes plays a key role in excitation-contraction coupling. To determine the area of the tubular membrane in relation to the area of the surface membrane, indirect measurements through the determination of membrane capac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdabaffc6982701a1db7f3ddbd471738
https://doi.org/10.1101/2021.11.12.468264
https://doi.org/10.1101/2021.11.12.468264
Autor:
Nuno Jorge Dourado Ramalho, Olga Švecová, Roman Kula, Milena Šimurdová, Jiří Šimurda, Markéta Bébarová
Publikováno v:
Pflugers Archiv : European journal of physiology. 474(3)
Bronchodilator aminophylline may induce atrial or less often ventricular arrhythmias. The mechanism of this proarrhythmic side effect has not been fully explained. Modifications of inward rectifier potassium (Kir) currents including I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46678d3d828eafde8f586990aabf3ba6
https://pubmed.ncbi.nlm.nih.gov/35084562
https://pubmed.ncbi.nlm.nih.gov/35084562
Publikováno v:
EP Europace. 23
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): Ministry of Education, Youth and Sports of the Czech Republic Introduction Aminophylline, a bronchodilator used in clinical practice to treat namely seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cf69819df5770bf7c39a559af26a628
https://doi.org/10.1093/europace/euab116.561
https://doi.org/10.1093/europace/euab116.561