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Autor:
Flavia Marinelli, Bohdan Ostash, Anton Kobylyanskyy, Nestor Zaburannyi, Olexandr Yushchuk, Victor Fedorenko, Liliya Horbal, Andriy Luzhetskyy
Publikováno v:
Journal of Biotechnology. 168:367-372
Actinoplanes teichomyceticus is the only known producer of the valuable glycopeptide antibiotic teicoplanin. Random mutagenesis and selection were extensively applied to teicoplanin producers, while the gene engineering methods were not used, because