Plasma Kallikrein-Activated TGF-β Is Prognostic for Poor Overall Survival in Patients with Pancreatic Ductal Adenocarcinoma and Associates with Increased Fibrogenesis.

Autor: Pedersen, Rasmus S., Nissen, Neel I., Jensen, Christina, Thorlacius-Ussing, Jeppe, Manon-Jensen, Tina, Olesen, Majken L., Langholm, Lasse L., Diab, Hadi M. H., Jorgensen, Lars N., Hansen, Carsten P., Chen, Inna M., Johansen, Julia S., Karsdal, Morten A., Willumsen, Nicholas

Publikováno v: Biomolecules (2218-273X); Sep2022, Vol. 12 Issue 9, p1315-1315, 13p

Harnessing phage display technology for generating fully human IgG antibodies that neutralise elapid neurotoxins

Autor: Karatt-Vellatt, Aneesh ^a, Laustsen, Andreas H. ^b, Masters, Edward W. ^a, Oscoz, Saioa ^c, Pus, Urska ^b, Knudsen, Cecilie ^b, Slavny, Peter ^a, Luther, Alice M. ^a, Leah, Rachael A. ^a, Grifiths, Daniel T. ^a, Olesen, Majken L. ^b, Lomonte, Bruno ^c, Gutiérrez, José María ^c, McCafferty, John ^{a, ∗}

Publikováno v: In Toxicon 1 February 2019 158 Supplement 1:S18-S18

Human oligoclonal recombinant antivenom against the black mamba (Dendroaspis polylepis)

Autor: Andreas Hougaard Laustsen, Aneesh Karatt-­Vellatt, Peter Slavny, Luther, Alice M., Olesen, Majken L., Masters, Edward W., Bruno Lomonte, José María Gutiérrez, John McCafferty

Publikováno v: Technical University of Denmark Orbit
Laustsen, A H, Karatt-­Vellatt, A, Slavny, P, M. Luther, A, L. Olesen, M, W. Masters, E, Lomonte, B, Gutiérrez, J M & McCafferty, J 2016, ' Human oligoclonal recombinant antivenom against the black mamba ( Dendroaspis polylepis ) ' PEGS Europe: Protein & Antibody Engineering Summit 2016, Lisbon, Portugal, 31/10/2016-04/11/2016, .

Snakebite envenoming is a major cause of death and morbidity in tropical parts of the world. Current therapies are based on animal-­derived antisera that are associated with a high degree of immunogenicity, high cost, and batch-to-batch variation. H

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https://orbit.dtu.dk/en/publications/038d97da-0eec-4e5e-8820-790652ab321d