Delineation and molecular characterization of acute myeloid leukemia patients with coduplication of FLT3 and MLL.

Autor: Olesen, Lene Hyldahl¹ lene.hyldahl.olesen@dadlnet.dk, Nyvold, Charlotte Guldborg¹, Aggerholm, Anni¹, Nørgaard, Jan Maxwell¹, Guldberg, Per², Hokland, Peter¹

Publikováno v: European Journal of Haematology. Sep2005, Vol. 75 Issue 3, p185-192. 8p.

Prospective application of a multiplex reverse transcription-polymerase chain reaction assay for the detection of balanced translocations in leukaemia: a single-laboratory study of 390 paediatric and adult patients

Autor: Olesen, Lene Hyldahl, Clausen, Niels, Dimitrijevic, Andreja, Kerndrup, Gitte, Kjeldsen, Eigil, Hokland, Peter

Publikováno v: Olesen, L H, Clausen, N, Dimitrijevic, A, Kerndrup, G, Kjeldsen, E & Hokland, P 2004, ' Prospective application of a multiplex reverse transcription-polymerase chain reaction assay for the detection of balanced translocations in leukaemia: a single-laboratory study of 390 paediatric and adult patients ', British Journal of Haematology, vol. 127, no. 1, pp. 59-66 . https://doi.org/10.1111/j.1365-2141.2004.05161.x

Udgivelsesdato: 2004-Oct The upfront application of molecular methods for identifying the fusion transcripts arising from balanced translocations in haematopoietic malignancies has several advantages: sensitivity is independent of its frequency, i.e.

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Promoter hypermethylation of the retinoic acid receptor β2 gene is frequent in acute myeloid leukaemia and associated with the presence of CBFβ– MYH11 fusion transcripts.

Autor: Rethmeier, Anita, Aggerholm, Anni, Olesen, Lene Hyldahl, Juhl-Christensen, Caroline, Nyvold, Charlotte Guldborg, Guldberg, Per, Hokland, Peter

Publikováno v: British Journal of Haematology; May2006, Vol. 133 Issue 3, p276-283, 8p, 3 Charts, 2 Graphs

WT1 gene expression: an excellent tool for monitoring minimal residual disease in 70% of acute myeloid leukaemia patients – results from a single-centre study.

Autor: Østergaard, Mette, Olesen, Lene Hyldahl, Hasle, Henrik, Kjeldsen, Eigil, Hokland, Peter

Publikováno v: British Journal of Haematology; Jun2004, Vol. 125 Issue 5, p590-600, 11p

Promoter hypermethylation of the retinoic acid receptor beta2 gene is frequent in acute myeloid leukaemia and associated with the presence of CBFbeta-MYH11 fusion transcripts.

Autor: Rethmeier A; Department of Haematology, Aarhus University Hospital, Aarhus, Denmark., Aggerholm A, Olesen LH, Juhl-Christensen C, Nyvold CG, Guldberg P, Hokland P

Publikováno v: British journal of haematology [Br J Haematol] 2006 May; Vol. 133 (3), pp. 276-83.