The mannan-binding lectin pathway and lung disease in cystic fibrosis-disfunction of mannan-binding lectin-asssociated serine protease 2 (MASP-2) may be a major modifier

Autor: Olesen, H. V., Jens Christian Jensenius, Steffensen, R., Steffen Thiel, Schiøtz, P. O.

Publikováno v: Olesen, H V, Jensenius, J C, Steffensen, R, Thiel, S & Schiøtz, P O 2006, ' The mannan-binding lectin pathway and lung disease in cystic fibrosis-disfunction of mannan-binding lectin-asssociated serine protease 2 (MASP-2) may be a major modifier ', Clin Immunol, vol. 121, pp. 324-31 .
Aarhus University

The lectin pathway of complement activation is initiated by mannan-binding lectin (MBL) or the ficolins through the common MBL-associated serine protease-2 (MASP-2). Deficiency of MBL has been associated with poorer outcome in cystic fibrosis (CF). W

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https://pure.au.dk/portal/da/publications/the-mannanbinding-lectin-pathway-and-lung-disease-in-cystic-fibrosisdisfunction-of-mannanbinding-lectinasssociated-serine-protease-2-masp2-may-be-a-major-modifier(809954b0-c7d7-11db-bee9-02004c4f4f50).html

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