Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Olesea Kosmatchev"'
Autor:
Olesea Kosmatchev, René Rahimoff, Gautier Arista, Yingqian Zhang, Angie Kirchner, Eva Korytiaková, Thomas Carell, Charlotte Ebert, Sarah Schiffers, Fabio Spada
Publikováno v:
Nature Chemical Biology
Epigenetic plasticity underpins cell potency, but the extent to which active turnover of DNA methylation contributes to such plasticity is not known, and the underlying pathways are poorly understood. Here we use metabolic labeling with stable isotop
Oxidative and non-oxidative active turnover of genomic methylcytosine in distinct pluripotent states
Autor:
Eva Korytiaková, Thomas Carell, Yingqian Zhang, Charlotte Ebert, Olesea Kosmatchev, René Rahimoff, Angie Kirchner, Sarah Schiffers, Fabio Spada
Epigenetic plasticity underpins cell potency, but the extent to which active turnover of DNA methylation contributes to such plasticity is not known and the underlying pathways are poorly understood. Here we use metabolic labelling with stable isotop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8197e5a9d4071fe020c1957318ab2b
Autor:
Fabio Spada, Olesea Kosmatchev, Markus Müller, Victor Brantl, Angie Kirchner, Thomas Carell, René Rahimoff, Toni Pfaffeneder
Publikováno v:
Journal of the American Chemical Society. 139:10359-10364
5-Formyl-dC (fdC) and 5-carboxy-dC (cadC) are newly discovered bases in the mammalian genome that are supposed to be substrates for base excision repair (BER) in the framework of active demethylation. The bases are recognized by the monofunctional th
Autor:
Jörg Nickelsen, Markus Müller, Thomas Carell, Sarah Schiffers, Jessica Steinbacher, Alexandra-Viola Bohne, René Rahimoff, Fabio Spada, Olesea Kosmatchev, Stylianos Michalakis, Charlotte Ebert
Publikováno v:
Angewandte Chemie International Edition. 56:11268-11271
Until recently, it was believed that the genomes of higher organisms contain, in addition to the four canonical DNA bases, only 5-methyl-dC (m5 dC) as a modified base to control epigenetic processes. In recent years, this view has changed dramaticall
Autor:
Sarah, Schiffers, Charlotte, Ebert, René, Rahimoff, Olesea, Kosmatchev, Jessica, Steinbacher, Alexandra-Viola, Bohne, Fabio, Spada, Stylianos, Michalakis, Jörg, Nickelsen, Markus, Müller, Thomas, Carell
Publikováno v:
Angewandte Chemie (International ed. in English). 56(37)
Until recently, it was believed that the genomes of higher organisms contain, in addition to the four canonical DNA bases, only 5-methyl-dC (m
Autor:
Nada Raddaoui, Mirko Wagner, Udo Müller, Heinrich Leonhardt, Caterina Brandmayr, Markus Müller, Olga Kotljarova, Cornelia G. Spruijt, Gengo Kashiwazaki, Barbara Steigenberger, Jessica Steinbacher, Stylianos Michalakis, Olesea Kosmatchev, Silvia K. Laube, Michiel Vermeulen, Fabio Spada, David Eisen, Stefan Schiesser, David Schuermann, Benjamin Hackner, Toni Pfaffeneder, Matthias Truss, Primo Schär, Thomas Carell
Publikováno v:
Nature Chemical Biology, 10, 7, pp. 574-81
Nature Chemical Biology
Nature Chemical Biology, 10, 574-81
Nature Chemical Biology
Nature Chemical Biology, 10, 574-81
Ten eleven translocation (Tet) enzymes oxidize the epigenetically important DNA base 5-methylcytosine (mC) stepwise to 5-hydroxymethylcytosine (hmC), 5-formylcytosine and 5-carboxycytosine. It is currently unknown whether Tet-induced oxidation is lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd224d64ebf3c0721dc60e3b002a046
https://hdl.handle.net/2066/135406
https://hdl.handle.net/2066/135406