Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Olena P. Ishchuk"'
Autor:
Xin Chen, Xiaowei Li, Boyang Ji, Yanyan Wang, Olena P. Ishchuk, Egor Vorontsov, Dina Petranovic, Verena Siewers, Martin K.M. Engqvist
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108322- (2022)
The production of recombinant proteins at high levels often induces stress-related phenotypes by protein misfolding or aggregation. These are similar to those of the yeast Alzheimer's disease (AD) model in which amyloid-β peptides (Aβ42) were accum
Externí odkaz:
https://doaj.org/article/f8a2cfb9152c4c64a1593650fa31380a
Autor:
Olena P. Ishchuk, Khadija Mohamed Ahmad, Katarina Koruza, Klara Bojanovič, Marcel Sprenger, Lydia Kasper, Sascha Brunke, Bernhard Hube, Torbjörn Säll, Thomas Hellmark, Birgitta Gullstrand, Christian Brion, Kelle Freel, Joseph Schacherer, Birgitte Regenberg, Wolfgang Knecht, Jure Piškur
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The yeast Candida glabrata is a major opportunistic pathogen causing mucosal and systemic infections in humans. Systemic infections caused by this yeast have high mortality rates and are difficult to treat due to this yeast’s intrinsic and frequent
Externí odkaz:
https://doaj.org/article/4ad7246ad5534d2bb55082619b29fb1c
Publikováno v:
Antibiotics, Vol 9, Iss 1, p 10 (2019)
The opportunistic human fungal pathogen Candida albicans relies on cell morphological transitions to develop biofilm and invade the host. In the current study, we developed new regulatory molecules, which inhibit the morphological transition of C. al
Externí odkaz:
https://doaj.org/article/6d6f587a88b64e4fbc2d48b297fa8adf
Autor:
Olena P, Ishchuk, Iván, Domenzain, Benjamín J, Sánchez, Facundo, Muñiz-Paredes, José L, Martínez, Jens, Nielsen, Dina, Petranovic
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(30)
Heme is an oxygen carrier and a cofactor of both industrial enzymes and food additives. The intracellular level of free heme is low, which limits the synthesis of heme proteins. Therefore, increasing heme synthesis allows an increased production of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c1e890a7e76c48cea6f991090be0636
https://pubmed.ncbi.nlm.nih.gov/35858410
https://pubmed.ncbi.nlm.nih.gov/35858410
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2477
After its discovery RNA interference (RNAi) has become a powerful tool to study gene functions in different organisms. RNAi has been applied at genome-wide scale and can be nowadays performed using high-throughput automated systems (robotics). The si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c58f1b80a5484f91a8d5f2e97236a749
https://pubmed.ncbi.nlm.nih.gov/35524125
https://pubmed.ncbi.nlm.nih.gov/35524125
Autor:
Zhenglong Gu, Josephine Wee, Yudong Li, Olena P. Ishchuk, Khadija Mohamed Ahmad, Ruoyu Zhang, Joshua A. Shapiro, Xiaoxian Guo, Zhe Wang, Jure Piškur
Publikováno v:
Methods. 176:82-90
The yeast Candida glabrata, an opportunistic human fungal pathogen, is the second most prevalent cause of candidiasis worldwide, with an infection incidence that has been increasing in the past decades. The completion of the C. glabrata reference gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2ca7baaacd1859266f228e64285368
https://doi.org/10.1016/j.ymeth.2019.05.002
https://doi.org/10.1016/j.ymeth.2019.05.002
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622568
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aa8d1cf89b60ef7526280797d54e479
https://doi.org/10.1007/978-1-0716-2257-5_18
https://doi.org/10.1007/978-1-0716-2257-5_18
Publikováno v:
Journal of Industrial Microbiology & Biotechnology
The use of thermotolerant yeast strains is an important attribute for a cost-effective high temperature biofermentation processes. However, the availability of thermotolerant yeast strains remains a major challenge. Isolation of temperature resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d1b8f4e8dd345a8c327e4cdf03e12c
https://doi.org/10.1007/s10295-018-2107-4
https://doi.org/10.1007/s10295-018-2107-4
Autor:
Olena P. Ishchuk, August T. Frost, Nathalie Laforge, José L. Martínez, Saki Matsumoto, Nélida Leiva Eriksson, Dina Petranovic, Facundo Muñiz-Paredes
Publikováno v:
Ishchuk, O P, Frost, A T, Muñiz-Paredes, F, Matsumoto, S, Laforge, N, Eriksson, N L, Martínez, J L & Petranovic, D 2021, ' Improved production of human hemoglobin in yeast by engineering hemoglobin degradation ', Metabolic Engineering, vol. 66, pp. 259-267 . https://doi.org/10.1016/j.ymben.2021.05.002
With the increasing demand for blood transfusions, the production of human hemoglobin (Hb) from sustainable sources is increasingly studied. Microbial production is an attractive option, as it may provide a cheap, safe, and reliable source of this pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35192cf4d0b97ec05d1fc6cb02bd4c7d
https://pubmed.ncbi.nlm.nih.gov/33984513
https://pubmed.ncbi.nlm.nih.gov/33984513
The opportunistic human fungal pathogen Candida albicans rely on cell morphological transitions to develop biofilm and invade the host. In the current study, we developed new regulatory molecules, which inhibit the morphological transition of C. albi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c1b311695dfefe9e7b19df63170080
https://doi.org/10.21203/rs.2.16042/v1
https://doi.org/10.21203/rs.2.16042/v1