Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Olena Kis"'
Autor:
Zuhal Ozcan, Brandon Shaw, Olena Kis, Xiaolan Fang, Jacquelyn Roberson, Travis Washburn, Mary Nyhuis
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101598- (2024)
Externí odkaz:
https://doaj.org/article/456c144eaccc4a1f927f6afbe739ad92
Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates
Autor:
Olena Kis, Rayan Kaedbey, Signy Chow, Arnavaz Danesh, Mark Dowar, Tiantian Li, Zhihua Li, Jessica Liu, Mark Mansour, Esther Masih-Khan, Tong Zhang, Scott V. Bratman, Amit M. Oza, Suzanne Kamel-Reid, Suzanne Trudel, Trevor J. Pugh
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Genetic profiling of multiple myeloma requires painful bone marrow biopsies. Here, the authors develop an alternative non-invasive method for sequencing of five oncogenes in circulating cell-free DNA from myeloma patients, demonstrating 96% concordan
Externí odkaz:
https://doaj.org/article/d52e507d56a94e48a45f62b403d8d6ed
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 15, Iss 2 (2012)
Purpose. African traditional medicinal plants, such as Sutherlandia frutescens have the potential to interact pharmacokinetically with the protease inhibitor class of antiretrovirals, thereby impacting on their safety and efficacy. The effects of ext
Externí odkaz:
https://doaj.org/article/5b727ff4d633414a9c3c9af67bf81c4f
Autor:
Brandon M. Shaw, Olena Kis
Publikováno v:
Cancer Metastasis Through the Lymphovascular System ISBN: 9783030930837
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a2a21e9f8039fb406b126e39c0aa964
https://doi.org/10.1007/978-3-030-93084-4_5
https://doi.org/10.1007/978-3-030-93084-4_5
Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing
Autor:
Signy Chow, Olena Kis, David T Mulder, Arnavaz Danesh, Jeff Bruce, Ting Ting Wang, Donna Reece, Nizar Bhalis, Paola Neri, Peter JB Sabatini, Jonathan Keats, Suzanne Trudel, Trevor J Pugh
Publikováno v:
Life Science Alliance. 6:e202201543
Multiple myeloma is a plasma cell neoplasm characterized by clonal immunoglobulin V(D)J signatures and oncogenic immunoglobulin gene translocations. Additional subclonal genomic changes are acquired with myeloma progression and therapeutic selection.
Publikováno v:
Computation, Vol 12, Iss 9, p 186 (2024)
This study proposes and theoretically substantiates a unique mathematical model for predicting the spread of infectious diseases using the example of COVID-19. The model is described by a special system of autonomous differential equations, which has
Externí odkaz:
https://doaj.org/article/d841680277fb4f80be9a6edd0dc52d06
Publikováno v:
Genes, chromosomescancerREFERENCES. 59(10)
The tuberous sclerosis genes and MTOR are increasingly being found to have important roles in novel subtypes of renal cancer, particularly emerging entities eosinophilic solid and cystic renal cell carcinoma (RCC) and high-grade oncocytic renal tumor
Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates
Autor:
Rayan Kaedbey, Arnavaz Danesh, Esther Masih-Khan, Jessica Liu, Tiantian Li, Signy Chow, Amit M. Oza, Suzanne Kamel-Reid, Zhihua Li, Suzanne Trudel, Scott V. Bratman, Olena Kis, Tong Zhang, Mark Mansour, Mark Dowar, Trevor J. Pugh
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications
Nature Communications
The requirement for bone-marrow aspirates for genomic profiling of multiple myeloma poses an obstacle to enrolment and retention of patients in clinical trials. We evaluated whether circulating cell-free DNA (cfDNA) analysis is comparable to molecula
Autor:
Sharon Walmsley, Satya Dandekar, M. Tozammel Hoque, Sumathi Sankaran-Walters, Reina Bendayan, Olena Kis
Publikováno v:
Antimicrobial agents and chemotherapy, vol 60, iss 5
This study investigated the effects of HIV-1 infection and antiretroviral therapy (ART) on the expression of intestinal drug efflux transporters, i.e., P-glycoprotein (Pgp), multidrug resistance-associated proteins (MRPs), and breast cancer resistanc
Autor:
Zhen Zhao, Tiantian Li, Anna Goldenberg, Olena Kis, John Douglas Mcpherson, Tiago Medina, Jessica Liu, Mark Mansour, Scott V. Bratman, Signy Chow, Rayjean J. Hung, Neil E. Fleshner, Ayelet Borgida, Philippe L. Bedard, Mark D. Minden, Trevor J. Pugh, Yadon Wang, Anna Spreafico, Gordon Fehringer, Steven Gallinger, Michael H.A. Roehrl, Zhuo Chen, Rajat Singhania, Ankur Chakravarthy, David Roulois, Andrea Arruda, Michael M. Hoffman, Ilias Ettayebi, Geoffrey Liu, Ting Ting Wang, Natasha B. Leighl, Tracy Murphy, Catherine A. O’Brien, Dianne Chadwick, Philip C. Zuzarte, Grainne M. O'Kane, Shu Yi Shen, Daniel D. De Carvalho
Publikováno v:
Nature
Nature, Nature Publishing Group, 2018, 563 (7732), pp.579-583. ⟨10.1038/s41586-018-0703-0⟩
Nature, 2018, 563 (7732), pp.579-583. ⟨10.1038/s41586-018-0703-0⟩
Nature, Nature Publishing Group, 2018, 563 (7732), pp.579-583. ⟨10.1038/s41586-018-0703-0⟩
Nature, 2018, 563 (7732), pp.579-583. ⟨10.1038/s41586-018-0703-0⟩
The use of liquid biopsies for cancer detection and management is rapidly gaining prominence1. Current methods for the detection of circulating tumour DNA involve sequencing somatic mutations using cell-free DNA, but the sensitivity of these methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7dcbbaf3e968ca094b955d13d9e0d5
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01974928
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01974928