Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Olena, Sivak"'
Autor:
Nakisa Tabrizian, Shaghayegh Nouruzi, Cassandra Jingjing Cui, Maxim Kobelev, Takeshi Namekawa, Ishana Lodhia, Amina Talal, Olena Sivak, Dwaipayan Ganguli, Amina Zoubeidi
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112937- (2023)
Summary: Lineage plasticity is a form of therapy-induced drug resistance. In prostate cancer, androgen receptor (AR) pathway inhibitors potentially lead to the accretion of tumor relapse with loss of AR signaling and a shift from a luminal state to a
Externí odkaz:
https://doaj.org/article/1783e6f100dc47309a0545ae19edabeb
Autor:
Shaghayegh Nouruzi, Dwaipayan Ganguli, Nakisa Tabrizian, Maxim Kobelev, Olena Sivak, Takeshi Namekawa, Daksh Thaper, Sylvan C. Baca, Matthew L. Freedman, Adeleke Aguda, Alastair Davies, Amina Zoubeidi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Following androgen receptor pathway inhibition prostate cancers can differentiate towards the neuroendocrine lineage. Here, the authors identify epigenetic alterations regulated by ASCL1 and suggest targeting ASCL1 to reverse the neuroendocrine pheno
Externí odkaz:
https://doaj.org/article/d4c48d0f84e74da9bf7129acd29bbc7f
Publikováno v:
Textiles, Vol 1, Iss 2, Pp 322-336 (2021)
In many textiles and fiber structures, the behavior of the material is determined by the structural arrangements of the fibers, their thickness and cross-section, as well as their material properties. Textiles are thin plates made of thin long yarns
Externí odkaz:
https://doaj.org/article/44ce5584ad8d44c8b4ac0065736abf4f
Autor:
Xia Wang, Kevin Gregory-Evans, Kishor M. Wasan, Olena Sivak, Xianghong Shan, Cheryl Y. Gregory-Evans
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 417-428 (2017)
Nonsense mutations leading to premature stop codons are common occurring in approximately 12% of all human genetic diseases. Thus, pharmacological nonsense mutation suppression strategies would be beneficial to a large number of patients if the drugs
Externí odkaz:
https://doaj.org/article/a6ed6384546f4f6480f73742489fcc8c
Autor:
Takeshi Namekawa, Joshua Scurll, Maxim Kobelev, Dwaipayan Ganguli, Olena Sivak, Martin Gleave, null Vancouver, null Canada, Eva Corey, Colm Morrissey, Amina Zoubeidi
Publikováno v:
Journal of Urology. 209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60faea0ae30da7154f9a9648a8bf180b
https://doi.org/10.1097/ju.0000000000003245.07
https://doi.org/10.1097/ju.0000000000003245.07
Autor:
Chiara Bostock, Dwaipayan Ganguli, David W. Goodrich, Soojin Kim, Amina Talal, Suzan Stelloo, Wilbert Zwart, Jennifer L. Bishop, Ladan Fazli, Marlous Hoogstraat, Henk G. van der Poel, Felix Y. Feng, Sahil Kumar, Meltem E. Omur, Himisha Beltran, Musaddeque Ahmed, Fatih Karaoğlanoğlu, Housheng Hansen He, Haojie Huang, Andries M. Bergman, Olena Sivak, Faraz Hach, Daksh Thaper, Martin E. Gleave, Takeshi Namekawa, Luke A. Selth, Amina Zoubeidi, Alastair H. Davies, Simon Linder, Wayne D. Tilley, Maxim Kobelev, Shaghayegh Nouruzi
Publikováno v:
Nature Cell Biology. 23:1023-1034
Cancers adapt to increasingly potent targeted therapies by reprogramming their phenotype. Here we investigated such a phenomenon in prostate cancer, in which tumours can escape epithelial lineage confinement and transition to a high-plasticity state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bf7dc549f2596c2bd670e3418ca4414
https://doi.org/10.1038/s41556-021-00743-5
https://doi.org/10.1038/s41556-021-00743-5
Publikováno v:
Textiles, Vol 1, Iss 16, Pp 322-336 (2021)
In many textiles and fiber structures, the behavior of the material is determined by the structural arrangements of the fibers, their thickness and cross-section, as well as their material properties. Textiles are thin plates made of thin long yarns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729dc397a8a98f9ac6364536a6f02dfb
https://doi.org/10.3390/textiles1020016
https://doi.org/10.3390/textiles1020016
Publikováno v:
Proceedings, Vol 22, Iss 1, p 90 (2019)
No targeted therapies exist against aggressive neuroendocrine tumors; hence, these patients are limited to platinum-based chemotherapy that has not advanced in over three decades. [...]
Externí odkaz:
https://doaj.org/article/f479151c6891444a8e09ee47a83b7033
Publikováno v:
Journal of Elasticity
Journal of Elasticity, Springer Verlag, In press
Journal of Elasticity, Springer Verlag, In press
In this paper, we study the asymptotic behavior of an $\varepsilon $ ε -periodic 3D stable structure made of beams of circular cross-section of radius $r$ r when the periodicity parameter $\varepsilon $ ε and the ratio ${r/\varepsilon }$ r / ε sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00823c22c1b67f4854f436b4927bd9b
https://doi.org/10.1007/s10659-021-09816-w
https://doi.org/10.1007/s10659-021-09816-w
Autor:
Daksh Thaper, Ravi Munuganti, Adeleke Aguda, Soojin Kim, Shengyu Ku, Olena Sivak, Sahil Kumar, Sepideh Vahid, Dwaipayan Ganguli, Himisha Beltran, Colm Morrissey, Eva Corey, Amina Zoubeidi
The increased incidence of treatment-emergent neuroendocrine prostate cancer (NEPC) is particularly alarming as this diagnosis is associated with poor prognosis. Despite initial responses to platinum-based chemotherapy, relapses are common and there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9375bc995eb9f52938f4d924e18dc2eb
https://doi.org/10.1101/2022.05.04.490172
https://doi.org/10.1101/2022.05.04.490172
