Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Oleksii Skorokhod"'
Autor:
Olga V. Vashchenko, Volodymyr P. Berest, Liliia V. Sviechnikova, Nataliya V. Kutsevol, Natalia A. Kasian, Dmitry S. Sofronov, Oleksii Skorokhod
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8691 (2024)
Gramicidin S (GS), one of the first discovered antimicrobial peptides, still shows strong antibiotic activity after decades of clinical use, with no evidence of resistance. The relatively high hemolytic activity and narrow therapeutic window of GS li
Externí odkaz:
https://doaj.org/article/25088340876246b180f550713b8bfc1c
Autor:
Evelin Schwarzer, Oleksii Skorokhod
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6145 (2024)
Post-translational modifications (PTMs) are essential for regulating protein functions, influencing various fundamental processes in eukaryotes. These include, but are not limited to, cell signaling, protein trafficking, the epigenetic control of gen
Externí odkaz:
https://doaj.org/article/4a230d60b94c4d7cbd2ff5425319710f
Publikováno v:
Antioxidants, Vol 12, Iss 7, p 1468 (2023)
Malaria is still the most important parasitic infectious disease. Numerous substances are known to have antimalarial activity; among them, artemisinin is the most widely used one, and artemisinin-based combination therapy (ACT) is recommended for the
Externí odkaz:
https://doaj.org/article/0779a28c689b432ea66fc5318479ab9c
Autor:
Oleksii Skorokhod, Vincenzo Triglione, Valentina Barrera, Giovanna Di Nardo, Elena Valente, Daniela Ulliers, Evelin Schwarzer, Gianfranco Gilardi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10232 (2023)
Malaria is a frequent parasitic infection becomes life threatening due to the disequilibrated immune responses of the host. Avid phagocytosis of malarial pigment hemozoin (HZ) and HZ-containing Plasmodium parasites incapacitates monocyte functions by
Externí odkaz:
https://doaj.org/article/5affdb9fb27c4bcc9f9386a83acf3244
Autor:
Oleksii Skorokhod, Valentina Barrera, Giorgia Mandili, Federica Costanza, Elena Valente, Daniela Ulliers, Evelin Schwarzer
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1259 (2021)
Malarial pigment hemozoin (HZ) generates the lipoperoxidation product 4-hydroxynonenal (4-HNE), which is known to cause dysregulation of the immune response in malaria. The inhibition of granulocyte macrophage colony-stimulating factor (GM-CSF)-depen
Externí odkaz:
https://doaj.org/article/bfad6fe00b3d4a62b6b653f0fd4638fa
Autor:
Gilardi, Oleksii Skorokhod, Vincenzo Triglione, Valentina Barrera, Giovanna Di Nardo, Elena Valente, Daniela Ulliers, Evelin Schwarzer, Gianfranco
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 10232
Malaria is a frequent parasitic infection becomes life threatening due to the disequilibrated immune responses of the host. Avid phagocytosis of malarial pigment hemozoin (HZ) and HZ-containing Plasmodium parasites incapacitates monocyte functions by
Autor:
Isabell Berneburg, Satyamaheshwar Peddibhotla, Kim C. Heimsch, Kristina Haeussler, Patrick Maloney, Palak Gosalia, Janina Preuss, Mahsa Rahbari, Oleksii Skorokhod, Elena Valente, Daniela Ulliers, Luigi Felice Simula, Kathrin Buchholz, Michael P. Hedrick, Paul Hershberger, Thomas D. Y. Chung, Michael R. Jackson, Evelin Schwarzer, Stefan Rahlfs, Lars Bode, Katja Becker, Anthony B. Pinkerton
Publikováno v:
Antimicrob Agents Chemother
In Plasmodium, the first two and rate-limiting enzymes of the pentose phosphate pathway, glucose 6-phosphate dehydrogenase (G6PD) and the 6-phosphogluconolactonase, are bifunctionally fused to a unique enzyme named GluPho, differing structurally and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b78be63f8ec7830ea15109c7201d38
https://hdl.handle.net/2318/1871678
https://hdl.handle.net/2318/1871678
Publikováno v:
Encyclopedia of Malaria ISBN: 9781461487579
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c8393f8078cc61bff1089919b76064
http://hdl.handle.net/2318/1530889
http://hdl.handle.net/2318/1530889
Publikováno v:
Encyclopedia of Malaria ISBN: 9781461487579
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e85e40e33ebf83ec0194c01f0705d6
http://hdl.handle.net/2318/1530915
http://hdl.handle.net/2318/1530915
Publikováno v:
Scopus-Elsevier
Oleksii Skorokhod
Europe PubMed Central
Oleksii Skorokhod
Europe PubMed Central
In vitro, human monocytes avidly ingest hemozoin (HZ) that modifies a number of monocyte functions. Inhibitory effects: inhibition of: PMA-elicited respiratory burst, ability to killing and repeat phagocytosis, activity of NADPH-oxidase and PKC, expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::aed76b56c835f763f2eee75678894d9c
http://hdl.handle.net/2318/1511648
http://hdl.handle.net/2318/1511648