Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Oleksandr, Platoshyn"'
Autor:
Yoshiomi Kobayashi, Michiko Shigyo, Oleksandr Platoshyn, Silvia Marsala, Tomohisa Kato, Naoki Takamura, Kenji Yoshida, Akiyoshi Kishino, Mariana Bravo-Hernandez, Stefan Juhas, Jana Juhasova, Hana Studenovska, Vladimir Proks, Shawn P. Driscoll, Thomas D. Glenn, Samuel L. Pfaff, Joseph D. Ciacci, Martin Marsala
Publikováno v:
Cell Transplantation, Vol 32 (2023)
One of the challenges in clinical translation of cell-replacement therapies is the definition of optimal cell generation and storage/recovery protocols which would permit a rapid preparation of cell-treatment products for patient administration. Besi
Externí odkaz:
https://doaj.org/article/53f0f5b81b344c76bd490c0f787e3315
Autor:
Michiko Shigyo, Yoshiomi Kobayashi, Oleksandr Platoshyn, Silvia Marsala, Tomohisa Kato Jr, Naoki Takamura, Kenji Yoshida, Akiyoshi Kishino, Mariana Bravo-Hernandez, Stefan Juhas, Jana Juhasova, Hana Studenovska, Vladimir Proks, Joseph D. Ciacci, Martin Marsala
Publikováno v:
Cell Transplantation, Vol 32 (2023)
The critical requirements in developing clinical-grade human-induced pluripotent stem cells–derived neural precursors (hiPSCs-NPCs) are defined by expandability, genetic stability, predictable in vivo post-grafting differentiation, and acceptable s
Externí odkaz:
https://doaj.org/article/4bcfd17772b643418267888175aa8508
Autor:
Dasa Bohaciakova, Marian Hruska-Plochan, Rachel Tsunemoto, Wesley D. Gifford, Shawn P. Driscoll, Thomas D. Glenn, Stephanie Wu, Silvia Marsala, Michael Navarro, Takahiro Tadokoro, Stefan Juhas, Jana Juhasova, Oleksandr Platoshyn, David Piper, Vickie Sheckler, Dara Ditsworth, Samuel L. Pfaff, Martin Marsala
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-19 (2019)
Abstract Background A well-characterized method has not yet been established to reproducibly, efficiently, and safely isolate large numbers of clinical-grade multipotent human neural stem cells (hNSCs) from embryonic stem cells (hESCs). Consequently,
Externí odkaz:
https://doaj.org/article/f87a5d79962b40ba83ca9d1341131d90
Autor:
Takahiro Tadokoro, Mariana Bravo-Hernandez, Kirill Agashkov, Yoshiomi Kobayashi, Oleksandr Platoshyn, Michael Navarro, Silvia Marsala, Atsushi Miyanohara, Tetsuya Yoshizumi, Michiko Shigyo, Volodymyr Krotov, Stefan Juhas, Jana Juhasova, Duong Nguyen, Helena Kupcova Skalnikova, Jan Motlik, Hana Studenovska, Vladimir Proks, Rajiv Reddy, Shawn P. Driscoll, Thomas D. Glenn, Taratorn Kemthong, Suchinda Malaivijitnond, Zoltan Tomori, Ivo Vanicky, Manabu Kakinohana, Samuel L. Pfaff, Joseph Ciacci, Pavel Belan, Martin Marsala
Publikováno v:
Molecular Therapy. 30:2722-2745
Second-order spinal cord excitatory neurons play a key role in spinal processing and transmission of pain signals to the brain. Exogenously induced change in developmentally imprinted excitatory neurotransmitter phenotypes of these neurons to inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f51e426ef6277241a74511014975950
https://doi.org/10.1016/j.ymthe.2022.04.023
https://doi.org/10.1016/j.ymthe.2022.04.023
Autor:
Shuo-Chien Ling, Somasish Ghosh Dastidar, Seiya Tokunaga, Wan Yun Ho, Kenneth Lim, Hristelina Ilieva, Philippe A Parone, Sheue-Houy Tyan, Tsemay M Tse, Jer-Cherng Chang, Oleksandr Platoshyn, Ngoc B Bui, Anh Bui, Anne Vetto, Shuying Sun, Melissa McAlonis-Downes, Joo Seok Han, Debbie Swing, Katannya Kapeli, Gene W Yeo, Lino Tessarollo, Martin Marsala, Christopher E Shaw, Greg Tucker-Kellogg, Albert R La Spada, Clotilde Lagier-Tourenne, Sandrine Da Cruz, Don W Cleveland
Publikováno v:
eLife, Vol 8 (2019)
Mutations in coding and non-coding regions of FUS cause amyotrophic lateral sclerosis (ALS). The latter mutations may exert toxicity by increasing FUS accumulation. We show here that broad expression within the nervous system of wild-type or either o
Externí odkaz:
https://doaj.org/article/04213ee8809d4946acefc96cd36ba9b2
Autor:
Yoshiomi Kobayashi, Michiko Shigyo, Oleksandr Platoshyn, Silvia Marsala, Tomohisa Kato, Naoki Takamura, Kenji Yoshida, Akiyoshi Kishino, Mariana Bravo-Hernandez, Stefan Juhas, Jana Juhasova, Hana Studenovska, Vladimir Proks, Shawn P. Driscoll, Thomas D. Glenn, Samuel L. Pfaff, Joseph D. Ciacci, Martin Marsala
One of the challenges in clinical translation of cell-replacement therapies is the definition of optimal cell generation and storage/recovery protocols which would permit a rapid preparation of cell-treatment products for patient administration. Besi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b9ecf3ac1d23b186656c93e245919d
https://escholarship.org/uc/item/6sx7k61r
https://escholarship.org/uc/item/6sx7k61r
Autor:
Jone Lopez-Erauskin, Mariana Bravo-Hernandez, Maximiliano Presa, Michael W. Baughn, Ze’ev Melamed, Melinda S. Beccari, Ana Rita Agra de Almeida Quadros, Aamir Zuberi, Karen Ling, Oleksandr Platoshyn, Elkin Niño-Jara, I. Sandra Ndayambaje, Olatz Arnold-Garcia, Melissa McAlonis-Downes, Larissa Cabrera, Jonathan W. Artates, Jennifer Ryan, Frank Bennett, Paymaan Jafar-nejad, Frank Rigo, Martin Marsala, Cathleen M. Lutz, Don W. Cleveland, Clotilde Lagier-Tourenne
The human mRNA most affected by TDP-43 loss-of-function is transcribed from theSTMN2gene and encodes stathmin-2 (also known as SCG10), whose loss is a neurodegenerative disease hallmark. Here using multiplein vivoapproaches, including transient antis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3fca87f97b78a3be286544a9b3838f6
https://doi.org/10.1101/2022.12.11.519794
https://doi.org/10.1101/2022.12.11.519794
Autor:
Jose A Corleto, Mariana Bravo-Hernández, Kota Kamizato, Osamu Kakinohana, Camila Santucci, Michael R Navarro, Oleksandr Platoshyn, Dasa Cizkova, Nadezda Lukacova, Julian Taylor, Martin Marsala
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144642 (2015)
The development of spinal hyper-reflexia as part of the spasticity syndrome represents one of the major complications associated with chronic spinal traumatic injury (SCI). The primary mechanism leading to progressive appearance of muscle spasticity
Externí odkaz:
https://doaj.org/article/30279f45710e4b0e9a5c214fd1b4e24b
Autor:
Jesse Wackerbarth, Martin Marsala, Oleksandr Platoshyn, David M. Roth, Atsushi Sawada, Piyush M. Patel, Joseph Leem, Hemal H. Patel, Junji Egawa, Brian P. Head, Alice E. Zemljic-Harpf, Shanshan Wang, Minyu Jian, Jan M. Schilling
Publikováno v:
The FASEB Journal. 33:7545-7554
Interventions that preserve motor neurons or restore functional motor neuroplasticity may extend longevity in amyotrophic lateral sclerosis (ALS). Delivery of neurotrophins may potentially revive degenerating motor neurons, yet this approach is depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d78392c7d59bc9d50c79ed7149c00f3
https://doi.org/10.1096/fj.201802652rr
https://doi.org/10.1096/fj.201802652rr
Autor:
Atsushi Miyanohara, Gene W. Yeo, Oleksandr Platoshyn, Martin Marsala, Maurice S. Swanson, Steven M. Blue, Florian Krach, Daniela M Roth, Curtis A. Nutter, David A. Nelles, James D. Thomas, Takahiro Tadokoro, Łukasz J. Sznajder, Haydee L Gutierrez, Patrick Liu, Stefan Aigner, Ranjan Batra
Publikováno v:
Nat Biomed Eng
Myotonic dystrophy type I (DM1) is a multisystemic autosomal-dominant inherited human disorder that is caused by CTG microsatellite repeat expansions (MREs) in the 3' untranslated region of DMPK. Toxic RNAs expressed from such repetitive sequences ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f08a08e63dc2110fe1123aabe232f3
https://europepmc.org/articles/PMC8241012/
https://europepmc.org/articles/PMC8241012/