Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Oleksandr, Khegai"'
Autor:
Lily McCarthy, Oleksandr Khegai, Jonathan Goldstein, Puneet Belani, Puneet Pawha, Shingo Kihira, Brian Mathew, Kapil Gururangan, Qing Hao, Anuradha Singh, Allison Navis, Bradley N Delman, Nathalie Jette, Priti Balchandani
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283614 (2023)
IntroductionCoronavirus 2019 (COVID-19) is known to affect the central nervous system. Neurologic morbidity associated with COVID-19 is commonly attributed to sequelae of some combination of thrombotic and inflammatory processes. The aim of this retr
Externí odkaz:
https://doaj.org/article/70b6305d616b4c69a938b3e134f32807
Autor:
Prodromos Parasoglou, Ricardo S. Osorio, Oleksandr Khegai, Zanetta Kovbasyuk, Margo Miller, Amanda Ho, Seena Dehkharghani, Thomas Wisniewski, Antonio Convit, Lisa Mosconi, Ryan Brown
Publikováno v:
Neuroimage: Reports, Vol 2, Iss 4, Pp 100121- (2022)
Background: Neurometabolic abnormalities and amyloid-beta plaque deposition are important early pathophysiologic changes in Alzheimer's disease (AD). This study investigated the relationship between high-energy phosphorus-containing metabolites, gluc
Externí odkaz:
https://doaj.org/article/bc6c712653d9421f8a3f831bf142d131
Autor:
Mackenzie T. Langan, Derek A. Smith, Gaurav Verma, Oleksandr Khegai, Sera Saju, Shams Rashid, Daniel Ranti, Matthew Markowitz, Puneet Belani, Nathalie Jette, Brian Mathew, Jonathan Goldstein, Claudia F. E. Kirsch, Laurel S. Morris, Jacqueline H. Becker, Bradley N. Delman, Priti Balchandani
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
While COVID-19 is primarily considered a respiratory disease, it has been shown to affect the central nervous system. Mounting evidence shows that COVID-19 is associated with neurological complications as well as effects thought to be related to neur
Externí odkaz:
https://doaj.org/article/ab530360094a4b4185f827386ba6cc0e
Autor:
Emily Rose Triolo, Oleksandr Khegai, Efe Ozkaya, Nicholas Rossi, Akbar Alipour, Lazar Fleysher, Priti Balchandani, Mehmet Kurt
Publikováno v:
Curr Protoc
Magnetic resonance elastography (MRE) is a technique for determining the mechanical response of soft materials using applied harmonic deformation of the material and a motion sensitive magnetic resonance imaging (MRI) sequence. Use of this technique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f4f3e108a923cc2038fa01c2fc15a4
https://pubmed.ncbi.nlm.nih.gov/35286023
https://pubmed.ncbi.nlm.nih.gov/35286023
Autor:
Pedro A. Gómez Damián, Jonathan I. Sperl, Martin A. Janich, Oleksandr Khegai, Florian Wiesinger, Steffen J. Glaser, Axel Haase, Markus Schwaiger, Rolf F. Schulte, Marion I. Menzel
Publikováno v:
Radiology Research and Practice, Vol 2014 (2014)
Hyperpolarized 13C imaging allows real-time in vivo measurements of metabolite levels. Quantification of metabolite conversion between [1-13C]pyruvate and downstream metabolites [1-13C]alanine, [1-13C]lactate, and [13C]bicarbonate can be achieved thr
Externí odkaz:
https://doaj.org/article/034f4f8c113f4ba599fef4df23732b1b
Autor:
Oleksandr Khegai, Wen-Chuin Hsu, Shu-Hang Ng, Jiun-Jie Wang, Yao-Liang Chen, Sung-Han Lin, Jur-Shan Cheng, Yi-Chun Chen, Chin-Chang Huang
Publikováno v:
Frontiers in Aging Neuroscience
Background: The loss of cortical neuron environment integrity is the hallmark of neurodegeneration diseases such as Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI). To reveal the microenvironment changes in cerebral cortex, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce80cce2cc853dd2abfe27d84e7c427
Publikováno v:
Magnetic resonance in medicine. 79(2)
To develop a high temporal resolution imaging method that measures muscle-specific phosphocreatine (PCr) resynthesis time constant (τWe developed a frequency-selective 3D non-Cartesian FLORET sequence to measure PCr with 17-mm nominal isotropic reso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d706e4bfe457d9513cdea94d7a29eb26
https://pubmed.ncbi.nlm.nih.gov/28560829
https://pubmed.ncbi.nlm.nih.gov/28560829
Autor:
Steffen J. Glaser, Oleksandr Khegai, Jan Henrik Ardenkjær-Larsen, Markus Schwaiger, Angela M. Otto, Marion I. Menzel, Axel Haase, Florian Wiesinger, Martin A. Janich, Eliane Farrell, Rolf F. Schulte
Publikováno v:
NMR in Biomedicine. 27:1256-1265
Hyperpolarization of [1-13C]pyruvate in solution allows real-time measurement of uptake and metabolism using MR spectroscopic methods. After injection and perfusion, pyruvate is taken up by the cells and enzymatically metabolized into downstream meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9815a68353504b92c728cb793dd07234
https://doi.org/10.1002/nbm.3174
https://doi.org/10.1002/nbm.3174
Autor:
Markus Schwaiger, Marion I. Menzel, Stephan G. Nekolla, Axel Haase, Martin A. Janich, Florian Wiesinger, Oleksandr Khegai, Rolf F. Schulte, Angela M. Otto, Eliane Farrell
Publikováno v:
Journal of Nuclear Medicine. 54:1113-1119
Abnormalities of tumor metabolism can be exploited for molecular imaging. PET imaging of (18)F-FDG is a well-established method using the avid glucose uptake of tumor cells. (13)C MR spectroscopic imaging (MRSI) of hyperpolarized [1-(13)C]pyruvate an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d43953e88b1607c5e357df6bfa08ec
https://doi.org/10.2967/jnumed.112.110825
https://doi.org/10.2967/jnumed.112.110825
Autor:
James S. Babb, Xuejiao Che, Niels D. Naimon, Leeor Alon, Jerzy Walczyk, Oleksandr Khegai, Ravinder R. Regatte, Ryan Brown, Prodromos Parasoglou
Publikováno v:
Magma (New York, N.Y.). 30(3)
To develop a low-cost pedal ergometer compatible with ultrahigh (7 T) field MR systems to reliably quantify metabolic parameters in human lower leg muscle using phosphorus magnetic resonance spectroscopy. We constructed an MR compatible ergometer usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29fdbee519265a8ff031d32fec5c5fe
https://pubmed.ncbi.nlm.nih.gov/28054143
https://pubmed.ncbi.nlm.nih.gov/28054143