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pro vyhledávání: '"Oleh А. Lukianov"'
Autor:
Georgiy G. Yakovenko, A. V. Bol’but, Marta S. Yagodkina-Yakovenko, Oleh А. Lukianov, M. V. Vovk
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:347-354
1-Alkyl-N-Boc-5-formylpyrazol-4-amines react with malononitrile and cyanoacetamide to form 5-amino-1H-pyrazolo[4,3-b]pyridine nitriles and amides, respectively. Cyclocondensation of the obtained derivatives with chloroacetaldehyde, bromotrifluoroacet
Publikováno v:
Chemistry of Heterocyclic Compounds. 55:1211-1216
N-Boc-protected 5-formyl-1H-pyrazol-4-amines react with malonic acid in pyridine in the presence of pyrrolidine at 45–50°С or with malonic acid monomethyl ether in the presence of pyrrolidine in AcOH under reflux with the formation of 5-oxo-4,5-d