Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Oleg Yegorov"'
Autor:
Changlin Yang, Vrunda Trivedi, Kyle Dyson, Tongjun Gu, Kate M. Candelario, Oleg Yegorov, Duane A. Mitchell
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Background The current standard of care treatments for medulloblastoma are insufficient as these do not take tumor heterogeneity into account. Newer, safer, patient-specific treatment approaches are required to treat high-risk medulloblastom
Externí odkaz:
https://doaj.org/article/8684278dd84441a8814e938fc4589449
Autor:
Christina A. von Roemeling, Jeet A. Patel, Savannah L. Carpenter, Oleg Yegorov, Changlin Yang, Alisha Bhatia, Bently P. Doonan, Rylynn Russell, Vrunda S. Trivedi, Kelena Klippel, Daniel H. Ryu, Adam Grippin, Hunter S. Futch, Yong Ran, Lan B. Hoang-Minh, Frances L. Weidert, Todd E. Golde, Duane A. Mitchell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract There are numerous mechanisms by which glioblastoma cells evade immunological detection, underscoring the need for strategic combinatorial treatments to achieve appreciable therapeutic effects. However, developing combination therapies is di
Externí odkaz:
https://doaj.org/article/bc9016cb7fb14ca0b35b39a6afc4265c
Autor:
Vrunda Trivedi, Changlin Yang, Kelena Klippel, Oleg Yegorov, Christina von Roemeling, Lan Hoang-Minh, Graeme Fenton, Elizabeth Ogando-Rivas, Paul Castillo, Ginger Moore, Kaytora Long-James, Kyle Dyson, Bently Doonan, Catherine Flores, Duane A. Mitchell
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Background Despite advancements in the successful use of immunotherapy in treating a variety of solid tumors, applications in treating brain tumors have lagged considerably. This is due, at least in part, to the lack of well-characterized an
Externí odkaz:
https://doaj.org/article/dd7adebdc5ef44db8761e569a2065eb9
Autor:
Bayli DiVita Dean, Tyler Wildes, Joseph Dean, Oleg Yegorov, Changlin Yang, David Shin, Connor Francis, John W Figg, Mathew Sebastian, Laura Falceto Font, Dan Jin, Alexandra Reid, Ginger Moore, Brandon Fernandez, Brandon Wummer, Carmelle Kuizon, Duane Mitchell, Catherine T Flores
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background Glioma-induced immune dysregulation of the hematopoietic system has been described in a limited number of studies. In this study, our group further demonstrates that gliomas interrupt the cellular differentiation programming and outcomes o
Externí odkaz:
https://doaj.org/article/ffbff475bf724a8eb19c4268e79f2c00
Autor:
Vanessa A Evans, Nitasha Kumar, Ali Filali, Francesco A Procopio, Oleg Yegorov, Jean-Philippe Goulet, Suha Saleh, Elias K Haddad, Candida da Fonseca Pereira, Paula C Ellenberg, Rafick-Pierre Sekaly, Paul U Cameron, Sharon R Lewin
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12, p e1003799 (2013)
Latently infected resting CD4(+) T cells are a major barrier to HIV cure. Understanding how latency is established, maintained and reversed is critical to identifying novel strategies to eliminate latently infected cells. We demonstrate here that co-
Externí odkaz:
https://doaj.org/article/f83812028fa3419e87c01200d2ce81e5
Autor:
Mehrnoosh Doroudchi, Oleg Yegorov, Tom Baumgartner, Anne-Elen Kernaleguen, Gaelle Breton, Michel L Ndongala, Mohamed-Rachid Boulassel, Jean-Pierre Routy, Nicole F Bernard, Rafick-Pierre Sékaly, Bader Yassine-Diab
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49562 (2012)
To determine the function and phenotype of CD8(+) T-cells targeting consensus and autologous sequences of entire HIV-1 Nef protein.Multiparameter flow cytometry-based analysis was used to evaluate the responses of two treatment naïve HIV-infected in
Externí odkaz:
https://doaj.org/article/0b5a5d92cbbb41ad8c40dcd22613903e
Autor:
Catherine T. Flores, Duane A. Mitchell, Carmelle Kuizon, Ginger Moore, Christina Pham, Rebecca Abraham, Bayli DiVita Dean, Adam Grippin, David Shin, Oleg Yegorov, Changlin Yang, Brandon Wummer, Connor Francis, Kyle A. Dyson, Tyler J. Wildes
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b273cfa02cc2cddc9347f1f4816d5d
https://doi.org/10.1158/1078-0432.22476854.v1
https://doi.org/10.1158/1078-0432.22476854.v1
Autor:
Catherine T. Flores, Duane A. Mitchell, Carmelle Kuizon, Ginger Moore, Christina Pham, Rebecca Abraham, Bayli DiVita Dean, Adam Grippin, David Shin, Oleg Yegorov, Changlin Yang, Brandon Wummer, Connor Francis, Kyle A. Dyson, Tyler J. Wildes
Purpose:Immunotherapy has been demonstrably effective against multiple cancers, yet tumor escape is common. It remains unclear how brain tumors escape immunotherapy and how to overcome this immune escape.Experimental Design:We studied KR158B-luc glio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7b5b8c7d63bf38b84f8abdf40920a7
https://doi.org/10.1158/1078-0432.c.6529502
https://doi.org/10.1158/1078-0432.c.6529502
Publikováno v:
Neuro-Oncology. 24:vii67-vii68
BACKGROUND Adoptive cellular therapy (ACT) using transfer of tumor-specific lymphocytes has emerged as a potent strategy for treatment of advanced and refractory malignancies. We have employed the use of total tumor RNA (TTRNA)-pulsed DCs in the ex v
Autor:
Vrunda Trivedi, Changlin Yang, Oleg Yegorov, Kelena Klippel, Graeme Fenton, Christina von Roemeling, Lan Hoang-Minh, Elizabeth Ogando-Rivas, Paul Castillo, Kyle Dyson, Ginger Moore, Duane Mitchell
Publikováno v:
Cancer Research. 83:5114-5114
Background: The development of successful immunotherapy targeting antigens in glioblastoma multiforme (GBM) remains a challenge owing to antigen heterogeneity and the low mutation burden in GBM. Cancer immunogenomics represents a complementary approa