Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Oleg V. Tsodikov"'
Autor:
Shogo Mori, Allan H. Pang, Nishad Thamban Chandrika, Sylvie Garneau-Tsodikova, Oleg V. Tsodikov
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Halogenase enzymes are of interest as halogenating tools for organic synthesis. Here the authors show that the bacterial FAD-dependent phenolic halogenase PltM chlorinates, brominates and iodinates a variety of substrates and reveal the structural ba
Externí odkaz:
https://doaj.org/article/3b1f388a92164bef93241673b250f59d
Autor:
David Schweer, J. Robert McCorkle, Jurgen Rohr, Oleg V. Tsodikov, Frederick Ueland, Jill Kolesar
Publikováno v:
Biomedicines, Vol 9, Iss 1, p 70 (2021)
Ovarian cancer is a highly deadly malignancy in which recurrence is considered incurable. Resistance to platinum-based chemotherapy bodes a particularly abysmal prognosis, underscoring the need for novel therapeutic agents and strategies. The use of
Externí odkaz:
https://doaj.org/article/63441dc373524a2db863d33e0a46b78f
Autor:
Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Adrian R. Ferré-D'Amaré, J. Christopher Fromme, K. Christopher Garcia, Rachelle Gaudet, Peng Gong, Stephen C. Harrison, Ekaterina E. Heldwein, Zongchao Jia, Robert J. Keenan, Andrew C. Kruse, Marc Kvansakul, Jason S. McLellan, Yorgo Modis, Yunsun Nam, Zbyszek Otwinowski, Emil F. Pai, Pedro José Barbosa Pereira, Carlo Petosa, C. S. Raman, Tom A. Rapoport, Antonina Roll-Mecak, Michael K. Rosen, Gabby Rudenko, Joseph Schlessinger, Thomas U. Schwartz, Yousif Shamoo, Holger Sondermann, Yizhi J. Tao, Niraj H. Tolia, Oleg V. Tsodikov, Kenneth D. Westover, Hao Wu, Ian Foster, James S. Fraser, Filipe R. N C. Maia, Tamir Gonen, Tom Kirchhausen, Kay Diederichs, Mercè Crosas, Piotr Sliz
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The validation and analysis of X-ray crystallographic data is essential for reproducibility and the development of crystallographic methods. Here, the authors describe a repository for crystallographic datasets and demonstrate some of the ways it cou
Externí odkaz:
https://doaj.org/article/72383da3679147f9a2668c703d709d2e
Autor:
Nishad Thamban Chandrika, Marina Y. Fosso, Oleg V. Tsodikov, Harry LeVine, Sylvie Garneau-Tsodikova
Publikováno v:
Molecules, Vol 25, Iss 1, p 77 (2019)
The fact that the number of people with Alzheimer’s disease is increasing, combined with the limited availability of drugs for its treatment, emphasize the need for the development of novel effective therapeutics for treating this brain disorder. H
Externí odkaz:
https://doaj.org/article/8bc25763144548d7ba12d30c60ae7761
Autor:
Shogo Mori, Allan H. Pang, Nishad Thamban Chandrika, Sylvie Garneau-Tsodikova, Oleg V. Tsodikov
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in Fig. 1, in which the labels ‘NADP+’ and ‘NADPH + H+’ were incorrectly given as ‘NADPH’ and ‘NADPH+ + H+’, respectively. This has been corrected in both the PDF and HTML versio
Externí odkaz:
https://doaj.org/article/22b42e70bf5a449d98cb906fb9477e87
Autor:
Allan H. Pang, Keith D. Green, Ankita Punetha, Nishad Thamban Chandrika, Kaitlind C. Howard, Sylvie Garneau-Tsodikova, Oleg V. Tsodikov
Publikováno v:
Biochemistry. 62:710-721
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7e9aed3d7120c6ccb237f54f2548987
https://doi.org/10.1021/acs.biochem.2c00658
https://doi.org/10.1021/acs.biochem.2c00658
Autor:
Skye Travis, Keith D. Green, Nishad Thamban Chandrika, Allan H. Pang, Patrick A. Frantom, Oleg V. Tsodikov, Sylvie Garneau-Tsodikova, Matthew K. Thompson
Publikováno v:
RSC Medicinal Chemistry. 14:947-956
High-throughput virtual screening has identified several new inhibitors of FosB from methicillin-resistant Staphylococcus aureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25777c5e6e948ad5bea0eb0090baafaf
https://doi.org/10.1039/d3md00113j
https://doi.org/10.1039/d3md00113j
Targeting thiol isomerase activity with zafirlukast to treat ovarian cancer from the bench to clinic
Autor:
Justine A. Gelzinis, Melanie K. Szahaj, Roelof H. Bekendam, Sienna E. Wurl, Megan M. Pantos, Christina A. Verbetsky, Alexandre Dufresne, Meghan Shea, Kaitlind C. Howard, Oleg V. Tsodikov, Sylvie Garneau‐Tsodikova, Jeffrey I. Zwicker, Daniel R. Kennedy
Publikováno v:
The FASEB Journal. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa6fe4e19c98184a9db4c40e299c17a9
https://doi.org/10.1096/fj.202201952r
https://doi.org/10.1096/fj.202201952r
Autor:
Keith D. Green, Allan H. Pang, Nishad Thamban Chandrika, Atefeh Garzan, Anthony D. Baughn, Oleg V. Tsodikov, Sylvie Garneau-Tsodikova
Publikováno v:
ACS Infectious Diseases. 8:757-767
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c08d0528bc0989b38f8001daeda29fb
https://doi.org/10.1021/acsinfecdis.1c00450
https://doi.org/10.1021/acsinfecdis.1c00450
Autor:
Skye Travis, Keith D. Green, Nathaniel C. Gilbert, Oleg V. Tsodikov, Sylvie Garneau-Tsodikova, Matthew K. Thompson
Publikováno v:
Biochemistry.
The Gram-positive pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0c26a6d2706fdc653bbeca09199467
https://pubmed.ncbi.nlm.nih.gov/36525630
https://pubmed.ncbi.nlm.nih.gov/36525630