Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Oleg V. Evgrafov"'
Autor:
Fasil Mathews, Victoria Sook Keng Tung, Robert Foronjy, Marina Boruk, James A. Knowles, Oleg V. Evgrafov
Publikováno v:
OTO Open, Vol 7, Iss 4, Pp n/a-n/a (2023)
Abstract Objective Single‐cell RNA‐sequencing of middle turbinate mucosa was performed to create the first single‐cell transcriptome catalog of this part of the human body. Study Design Basic science research. Setting Single center, tertiary ca
Externí odkaz:
https://doaj.org/article/cb09bba00e04455b971a9640fa6208c7
Autor:
Kun Yang, Oleg V. Evgrafov
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/6499b52c82914ec8a6005ddbbd7153e6
Autor:
Victoria Sook Keng Tung, Fasil Mathews, Marina Boruk, Gabrielle Suppa, Robert Foronjy, Michele T. Pato, Carlos N. Pato, James A. Knowles, Oleg V. Evgrafov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15339 (2023)
The study of neurodevelopmental molecular mechanisms in schizophrenia requires the development of adequate biological models such as patient-derived cells and their derivatives. We previously utilized cell lines with neural progenitor properties (CNO
Externí odkaz:
https://doaj.org/article/dd235ebf451e4407806053a91ed56c25
Publikováno v:
Microorganisms, Vol 9, Iss 12, p 2584 (2021)
Yeast PARK9 (YPK9) shares homology with human ATP13A2, which encodes a polyamine transporter implicated in juvenile forms of Parkinson’s disease. We used YPK9 to gain insight into how ATP13A2 affects cell growth and sensitivity to oxidative stress.
Externí odkaz:
https://doaj.org/article/b5f25ade72c84d5ab5bc3d7a327aef01
Autor:
Lingling Shi, Yunfei Guo, Chengliang Dong, John Huddleston, Hui Yang, Xiaolu Han, Aisi Fu, Quan Li, Na Li, Siyi Gong, Katherine E. Lintner, Qiong Ding, Zou Wang, Jiang Hu, Depeng Wang, Feng Wang, Lin Wang, Gholson J. Lyon, Yongtao Guan, Yufeng Shen, Oleg V. Evgrafov, James A. Knowles, Francoise Thibaud-Nissen, Valerie Schneider, Chack-Yung Yu, Libing Zhou, Evan E. Eichler, Kwok-Fai So, Kai Wang
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Short-read sequencing has inherent limitations in the characterisation of long repeat elements. Shi and Guo et al.combine single-molecule real-time sequencing and IrysChip to construct a Chinese reference genome that fills many gaps in the reference
Externí odkaz:
https://doaj.org/article/0e208353827a44778269d1b511fa9076
Autor:
Anna A. Igolkina, Chris Armoskus, Jeremy R. B. Newman, Oleg V. Evgrafov, Lauren M. McIntyre, Sergey V. Nuzhdin, Maria G. Samsonova
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Schizophrenia (SCZ) is a psychiatric disorder of unknown etiology. There is evidence suggesting that aberrations in neurodevelopment are a significant attribute of schizophrenia pathogenesis and progression. To identify biologically relevant molecula
Externí odkaz:
https://doaj.org/article/04f61eca407947e8aae705e150efb168
Autor:
Jessica J. DeWitt, Nicole Grepo, Brent Wilkinson, Oleg V. Evgrafov, James A. Knowles, Daniel B. Campbell
Publikováno v:
Genes, Vol 7, Iss 10, p 76 (2016)
We previously identified the long noncoding RNA (lncRNA) MSNP1AS (moesin pseudogene 1, antisense) as a functional element revealed by genome wide significant association with autism spectrum disorder (ASD). MSNP1AS expression was increased in the pos
Externí odkaz:
https://doaj.org/article/531c942a0a0d4f39815b91fc54fbafd0
Autor:
Fasil Mathews, Victoria Sook Keng Tung, Robert Foronjy, Marina Boruk, James A Knowles, Oleg V Evgrafov
ImportanceElucidation of the cellular makeup of the middle turbinate provides a foundation for future studies of pathogenesis of sinonasal disease. Neural progenitors and pluripotent basal cells found in middle turbinate mucosa potentially can be use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98a6539f922e1a0e16c91231f8e37671
https://doi.org/10.1101/2022.10.09.511503
https://doi.org/10.1101/2022.10.09.511503
Autor:
Pat Levitt, Jennifer Herstein, Kimberly A. Aldinger, Andrew E. Timms, James W. MacDonald, James A. Knowles, Oleg V. Evgrafov, Theo K. Bammler, Hanna K. McNamara
Publikováno v:
Scientific Data, Vol 7, Iss 1, Pp 1-8 (2020)
Scientific Data
Scientific Data
Rett syndrome is an X-linked neurodevelopmental disorder caused by mutation in the methyl-CpG-binding protein 2 gene (MECP2) in the majority of cases. We describe an RNA sequencing dataset of postmortem brain tissue samples from four females clinical
Autor:
António Macedo, Patrick F. Sullivan, Pamela Sklar, Diana O. Perkins, David L. Braff, Eric D. Achtyes, Roman Kotov, Eli A. Stahl, Maria Helena Pinto de Azevedo, Colm O'Dushlaine, Elizabeth Bevilacqua, Célia Barreto Carvalho, Marquis P. Vawter, James Nemesh, Edward M. Scolnick, Jacquelyn L. Meyers, Jorge Valderrama, Shaun Purcell, Becky Kinkead, Douglas S. Lehrer, Peter F. Buckley, William Byerley, Humberto Nicolini, Fabio Macciardi, James L. Kennedy, Michael Escamilla, Ruben C. Gur, Dolores Malaspina, Ashley Dumont, Giulio Genovese, Helena Medeiros, Penelope Georgakopoulos, Colony Abbott, Diane Gage, Carlos N. Pato, Brooke M. Sklar, Roseann E. Peterson, Jordan W. Smoller, Steven A. McCarroll, Raquel E. Gur, Ayman H. Fanous, Laura J. Fochtmann, Stephen R. Marder, Sinéad B. Chapman, Mark Hyman Rapaport, James A. Knowles, Michele T. Pato, Janet L. Sobell, Evelyn J. Bromet, Conrad Iyegbe, Lynn E DeLisi, Jeffrey J. Rakofsky, Oleg V. Evgrafov, Jennifer L. Moran, Christopher P. Morley, Tim B. Bigdeli, Richard A. Belliveau, Mantosh J. Dewan
Publikováno v:
Molecular Psychiatry
Schizophrenia is a common, chronic and debilitating neuropsychiatric syndrome affecting tens of millions of individuals worldwide. While rare genetic variants play a role in the etiology of schizophrenia, most of the currently explained liability is