Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Oleg Shinkazh"'
Autor:
Dmitriy Fedorenko, Nuno D.S. Pinto, Jonathan Walko, Amit K. Dutta, Oleg Shinkazh, Jasmine Tan, Mark Brower, Andrew L. Zydney
Publikováno v:
Biotechnology and Bioengineering. 117:646-653
Continuous countercurrent tangential chromatography (CCTC) enables steady-state continuous bioprocessing with low-pressure operation and high productivity. CCTC has been applied to initial capture of monoclonal antibodies (mAb) from clarified cell cu
Performance optimization of continuous countercurrent tangential chromatography for antibody capture
Publikováno v:
Biotechnology Progress. 32:430-439
Recent studies have demonstrated that continuous countercurrent tangential chromatography (CCTC) can effectively purify monoclonal antibodies from clarified cell culture fluid. CCTC has the potential to overcome many of the limitations of conventiona
Autor:
Andrew Tustian, Achyuta Teella, Boris Napadensky, Travis Tran, Ada W. Zhang, Oleg Shinkazh, Andrew L. Zydney, Gary Brookhart, Philip A. Ropp, Amit K. Dutta
Publikováno v:
Journal of Biotechnology. 213:54-64
Recent studies using simple model systems have demonstrated that continuous countercurrent tangential chromatography (CCTC) has the potential to overcome many of the limitations of conventional Protein A chromatography using packed columns. The objec
Publikováno v:
Separation Science and Technology. 48:1289-1297
Recent increases in antibody titers have generated renewed interest in lower-cost continuous chromatographic processes for antibody purification. The objective of this study was to design, build, and test a continuous countercurrent tangential chroma
Autor:
Daniar Hussain, Matthew R. Long, Oleg Shinkazh, Andrew L. Zydney, Morgan Barth, Dharmesh M. Kanani
Publikováno v:
Biotechnology and Bioengineering. 108:582-591
Recent advances in cell culture technology have created significant pressure on the downstream purification process, leading to a “downstream bottleneck” in the production of recombinant therapeutic proteins for the treatment of cancer, genetic d