Zobrazeno 1 - 10
of 907
pro vyhledávání: '"Oleg N, Chupakhin"'
Autor:
Egor A. Nikiforov, Nailya F. Vaskina, Timofey D. Moseev, Mikhail V. Varaksin, Valery N. Charushin, Oleg N. Chupakhin
Publikováno v:
Chemistry, Vol 5, Iss 3, Pp 1477-1487 (2023)
A synthetic strategy based on reactions of cyclic imine oxides, namely 2H-imidazole 1-oxides, with thiophenols mediated by acetyl chloride was successfully applied as a convenient tool to obtain a series of novel azaheterocyclic molecules, including
Externí odkaz:
https://doaj.org/article/9ad6fc95b69646ad99a7e8ef40614258
Autor:
Galina F. Makhaeva, Nadezhda V. Kovaleva, Elena V. Rudakova, Natalia P. Boltneva, Sofya V. Lushchekina, Tatiana Yu Astakhova, Elena N. Timokhina, Olga G. Serebryakova, Alexander V. Shchepochkin, Maxim A. Averkov, Irina A. Utepova, Nadezhda S. Demina, Eugene V. Radchenko, Vladimir A. Palyulin, Vladimir P. Fisenko, Sergey O. Bachurin, Oleg N. Chupakhin, Valery N. Charushin, Rudy J. Richardson
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
We investigated the inhibitory activities of novel 9-phosphoryl-9,10-dihydroacridines and 9-phosphorylacridines against acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and carboxylesterase (CES). We also studied the abilities of the new co
Externí odkaz:
https://doaj.org/article/19995bc7cc79494d8334518aebc4070e
Autor:
Ramil F. Fatykhov, Igor A. Khalymbadzha, Ainur D. Sharapov, Anastasia P. Potapova, Ekaterina S. Starnovskaya, Dmitry S. Kopchuk, Oleg N. Chupakhin
Publikováno v:
Chimica Techno Acta, Vol 10, Iss 2 (2023)
Herein, we report a convenient one-pot synthesis of 1,2,4-triazinyl derivatives of benzocoumarins. The proposed approach consists in the nucleophilic addition of tetrahydrobenzo annulated dimethoxycoumarin to 1,2,4-triazines followed by double oxidat
Externí odkaz:
https://doaj.org/article/4b569c0bd4cd49bea6149a6cbfdfe7ca
Autor:
Anna V. Korotina, Svetlana G. Tolshchina, Rashida I. Ishmetova, Natalya P. Evstigneeva, Natalya A. Gerasimova, Natalya V. Zilberberg, Nikolay V. Kungurov, Gennady L. Rusinov, Oleg N. Chupakhin, Valery N. Charushin
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 18, Iss 1, Pp 243-250 (2022)
A series of novel [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines has been synthesized through oxidation reaction of the corresponding 3,6-disubstituted 1,2,4,5-tetrazines bearing amidine fragments. It is shown that the heterocyclic systems obtained can be
Externí odkaz:
https://doaj.org/article/6f01ef236f924e68836f223763969a0d
Autor:
Aluru Rammohan, Albert F. Khasanov, Dmitry S. Kopchuk, Duvvuru Gunasekar, Grigory V. Zyryanov, Oleg N. Chupakhin
Publikováno v:
Natural Products and Bioprospecting, Vol 12, Iss 1, Pp 1-21 (2022)
Abstract The development of highly facile synthetic procedures for the expedient synthesis of complex natural molecules is always in demand. As this aspect, the Diels–Alder reaction (DAR) has a versatile approach to the synthesis of complex natural
Externí odkaz:
https://doaj.org/article/c53c88a92a474f10ab18709a720d64b1
Autor:
Yuriy A. Kvashnin, Egor V. Verbitskiy, Ekaterina F. Zhilina, Gennady L. Rusinov, Oleg N. Chupakhin, Valery N. Charushin
Publikováno v:
ACS Omega, Vol 5, Iss 25, Pp 15681-15690 (2020)
Externí odkaz:
https://doaj.org/article/1dcc78611dcf41f5a9ea4694a34be87c
Autor:
Yuriy A. Kvashnin, Egor V. Verbitskiy, Oleg S. Eltsov, Pavel A. Slepukhin, Alexey R. Tameev, Natalia V. Nekrasova, Gennady L. Rusinov, Jean-Michel Nunzi, Oleg N. Chupakhin, Valery N. Charushin
Publikováno v:
ACS Omega, Vol 5, Iss 14, Pp 8200-8210 (2020)
Externí odkaz:
https://doaj.org/article/969e8caf36cd4dffa70e3c6a3e78ea5c
Autor:
Ainur D. Sharapov, Ramil F. Fatykhov, Igor A. Khalymbadzha, Grigory V. Zyryanov, Oleg N. Chupakhin, Mikhail V. Tsurkan
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2839 (2023)
This review summarizes and systematizes the literature on the anti-HIV activity of plant coumarins with emphasis on isolation and the mechanism of their antiviral action. This review summarizes the information on the anti-HIV properties of simple cou
Externí odkaz:
https://doaj.org/article/8019c92202b84361bab733932c4cd81c
Autor:
Alexey P. Krinochkin, Maria I. Valieva, Ekaterina S. Starnovskaya, Yaroslav K. Shtaitz, Dmitry S. Kopchuk, Olga S. Taniya, Grigory A. Kim, Vadim A. Shevyrin, Grigory V. Zyryanov, Oleg N. Chupakhin
Publikováno v:
Molecules, Vol 28, Iss 2, p 724 (2023)
New Tb(III) and Eu(III) complexes based on aryl-2,2′-bipyridine ligands with a cyclic DO3A chelating unit appended in the alpha position of the bipyridine core were synthesized. The photophysical properties of these complexes were compared with tho
Externí odkaz:
https://doaj.org/article/1b5ef34876834f7c8b1e286bcaf1f81a
Autor:
Elizaveta A. Dutysheva, Irina A. Utepova, Maria A. Trestsova, Alexander S. Anisimov, Valery N. Charushin, Oleg N. Chupakhin, Boris A. Margulis, Irina V. Guzhova, Vladimir F. Lazarev
Publikováno v:
Data in Brief, Vol 39, Iss , Pp 107562- (2021)
These data are related to our previous paper “Synthesis and approbation of new neuroprotective chemicals of pyrrolyl- and indolylazine classes in a cell model of Alzheimer's disease” (Dutysheva et al., 2021), in which we demonstrate neuroprotecti
Externí odkaz:
https://doaj.org/article/7b9e6d3cd84847e3a178db7ff8b6c459