Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Oleg Melnyk"'
Autor:
Francesco Terzani, Chen Wang, Simindokht Rostami, Rémi Desmet, Benoît Snella, Magalie Sénéchal, Birgit Wiltschi, Jérôme Vicogne, Oleg Melnyk, Vangelis Agouridas
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103390- (2024)
Summary: The development of fast ligation chemistries for the site-specific modification of proteins has become a major focus in chemical biology. We describe steps for preparing an oxalyl thioester precursor in the form of an N-oxalyl perhydro-1,2,5
Externí odkaz:
https://doaj.org/article/d21f4b7ccb1f466ab10f0348eff26624
Autor:
Nathalie Ollivier, Magalie Sénéchal, Rémi Desmet, Benoît Snella, Vangelis Agouridas, Oleg Melnyk
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Phosphorylation is a mechanism used by cells to promote proteins-biomolecules association. Here, the authors show the effect of the interactions between proteins equipped with positively charged arginines and peptides harbouring negatively charged ph
Externí odkaz:
https://doaj.org/article/35af3717c05a41b8b1e9a8f432c76bde
Autor:
Vincent Girod, Robin Houssier, Karin Sahmer, Marie-José Ghoris, Stéphanie Caby, Oleg Melnyk, Colette Dissous, Vincent Senez, Jérôme Vicogne
Publikováno v:
Royal Society Open Science, Vol 9, Iss 11 (2022)
The discovery of novel antihelmintic molecules to combat the development and spread of schistosomiasis, a disease caused by several Schistosoma flatworm species, mobilizes significant research efforts worldwide. With a limited number of biochemical a
Externí odkaz:
https://doaj.org/article/2690d586daa84239a50596d798fe2b81
Autor:
Vincent Diemer, Nathalie Ollivier, Bérénice Leclercq, Hervé Drobecq, Jérôme Vicogne, Vangelis Agouridas, Oleg Melnyk
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Control of cysteine reactivity is of paramount importance for the synthesis of proteins using native chemical ligation. Here, the authors report a readily cleavable N-selenoethyl group attached to cysteine and apply it to the modular assembly of line
Externí odkaz:
https://doaj.org/article/024061c5d12c406ea5bee1e0d5dcde35
Autor:
Nathalie Ollivier, Thomas Toupy, Ruben C. Hartkoorn, Rémi Desmet, Jean-Christophe M. Monbaliu, Oleg Melnyk
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Flow-based peptide synthesis is a well-established method, yet difficult to combine with native chemical ligation (NCL), the go-to method for peptide cyclization. Here, the authors developed a microfluidic procedure for peptide cyclization within min
Externí odkaz:
https://doaj.org/article/b5a06ec209fc4f7f99553330779adfca
Autor:
Florent Kerdraon, Gemma Bogard, Benoît Snella, Hervé Drobecq, Muriel Pichavant, Vangelis Agouridas, Oleg Melnyk
Publikováno v:
Molecules, Vol 26, Iss 5, p 1386 (2021)
While thiol-based catalysts are widely employed for chemical protein synthesis relying on peptide thioester chemistry, this is less true for selenol-based catalysts whose development is in its infancy. In this study, we compared different selenols de
Externí odkaz:
https://doaj.org/article/9b8108819892425dbfa6b4ba916dbff4
Publikováno v:
Organic Letters. 25:2696-2700
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f073b37606fb2fe5180a439a8750bbf
https://doi.org/10.1021/acs.orglett.3c00796
https://doi.org/10.1021/acs.orglett.3c00796
Publikováno v:
Folia Pomeranae Universitatis Technologiae Stetinensis Agricultura, Alimentaria, Piscaria et Zootechnica. 363:31-39
The aim of the research was to determine the productivity and reproduction indices of the Polish Holstein-Friesian Black-and-White variety cows in three consecutive lactations. The research was carried out in the Experimental Station of the National
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc22796ddefbfc9654d6e3da4282c4d6
https://doi.org/10.21005/aapz2022.62.2.3
https://doi.org/10.21005/aapz2022.62.2.3
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, 2022, 87 (14), pp.9426-9430. ⟨10.1021/acs.joc.2c00934⟩
Journal of Organic Chemistry, 2022, 87 (14), pp.9426-9430. ⟨10.1021/acs.joc.2c00934⟩
International audience; The arylthiol 4-mercaptophenylacetic acid (MPAA) is a powerful catalyst of selenosulfide bond reduction by the triarylphosphine 3,3′,3″-phosphanetriyltris(benzenesulfonic acid) trisodium salt (TPPTS). Both reagents are wat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042647de62a465563b3256cf194b1b86
https://doi.org/10.1021/acs.joc.2c00934
https://doi.org/10.1021/acs.joc.2c00934
Autor:
Rémi Desmet, Céline Boidin‐Wichlacz, Reda Mhidia, Aurélie Tasiemski, Vangelis Agouridas, Oleg Melnyk
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2023, ⟨10.1002/anie.202302648⟩
Angewandte Chemie International Edition, 2023, ⟨10.1002/anie.202302648⟩
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f50e303d18533e2c26a00df6d74ec7
https://doi.org/10.1002/anie.202302648
https://doi.org/10.1002/anie.202302648