Výsledky vyhledávání - "Oleg L. Chagunava"

High frequency of BRCA1 5382insC mutation in Russian breast cancer patients

Autor: Cees J. Cornelisse, Evgeny N. Imyanitov, Oleg L. Chagunava, Ekatherina Sh. Kuligina, Dmitry Yu. Trofimov, Matsko De, Vladimir Semiglazov, Peter Devilee, Natalia V. Mitiushkina, Aglaya G. Iyevleva, Elena M. Bit-Sava, Yulia M. Ulibina, Anna P. Sokolenko, Elena V. Chekmariova, Alexandr V. Togo, Konstantin G. Buslov, Maxim E. Rozanov, Evgeny N. Suspitsin

Publikováno v: European Journal of Cancer. 42:1380-1384

BRCA1 5382insC variant was repeatedly detected in Jewish breast cancer (BC) families residing in USA and Israel as well as in non-Jewish familial BC patients from Poland, Latvia, Hungary, Russia and some other European countries. However, the distrib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77c037911244a954bdd689bd1227eb7
https://doi.org/10.1016/j.ejca.2006.01.050

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CHEK2 1100delC mutation is frequent among Russian breast cancer patients

Autor: Vladimir Semiglazov, Evgeny N. Imyanitov, Anna P. Sokolenko, Dmitry A. Voskresenskiy, Matsko De, Yulia M. Ulibina, Natalia V. Mitiushkina, Maxim E. Rozanov, Aglaya G. Iyevleva, Oleg L. Chagunava, Peter Devilee, Alexandr V. Togo, Konstantin G. Buslov, Elena V. Chekmariova, Cees J. Cornelisse

Publikováno v: Breast Cancer Research and Treatment. 100:99-102

This study was aimed to assess the role of CHEK2 1100delC mutation in breast cancer (BC) predisposition in Russia. The 1100delC allele was detected in 14/660 (2.1%) unilateral BC cases and in 8/155 (5.2%) patients with the bilateral form of the disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79cf2bfc46a647bda81991ffbf501a67
https://doi.org/10.1007/s10549-006-9227-7

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NBS1 657del5 mutation may contribute only to a limited fraction of breast cancer cases in Russia

Autor: Anna P. Sokolenko, Evgeny N. Suspitsin, Cees J. Cornelisse, Elena M. Bit-Sava, Peter Devilee, Oleg L. Chagunava, Yulia R. Lazareva, Vladimir Semiglazov, Konstantin G. Buslov, Matsko De, Evgeny N. Imyanitov, Turkevich Ea, Aglaya G. Iyevleva, Alexandr V. Togo, Kaido P. Hanson, Ekatherina Sh. Kuligina, Elena V. Chekmariova

Publikováno v: International Journal of Cancer. 114:585-589

The gene for Nijmegen chromosomal breakage syndrome (NBS1) plays a role in a variety of processes protecting chromosomal stability. Recently, it was suggested in a Polish case-control study that the founder hypomorphic mutation in NBS1, 657del5, whic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91e89dd1b0b49755e745fe5922b0e34
https://doi.org/10.1002/ijc.20765

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Distinct prevalence of the CYP19 Δ3(TTTA)7 allele in premenopausal versus postmenopausal breast cancer patients, but not in control individuals

Autor: Evgeniya V. Belogubova, Ekatherina Sh. Kuligina, Evgeny N. Suspitsin, E.P. Sokolov, Charles Theillet, Alexandr V. Togo, M. Grigoriev, K. Pozharisski, Oleg L. Chagunava, Evgeny N. Imyanitov, Kaido P. Hanson, L. M. Berstein

Publikováno v: European Journal of Cancer. 38:1911-1916

The CYP19 gene encodes the enzyme aromatase, which plays a key role in the conversion of androgens to oestrogens. A polymorphism in CYP19 in intron 4 (TTTA)n has been reported to be associated with breast cancer (BC) risk, although conflicting eviden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50bc54f2024eddcf9008119413a6939f
https://doi.org/10.1016/s0959-8049(02)00149-1

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CYP17 polymorphism in the groups of distinct breast cancer susceptibility: comparison of patients with the bilateral disease vs. monolateral breast cancer patients vs. middle-aged female controls vs. elderly tumor-free women

Autor: Maxim Yu. Grigoriev, Evgeny N. Suspitsin, Kaido P. Hanson, Kazimir M Pozharisskiy, Charles Theillet, Evgeny N. Imyanitov, Ekatherina Sh. Kuligina, Alexandr V. Togo, Lev M Berstein, Oleg L. Chagunava

Publikováno v: Cancer Letters. 156:45-50

The CYP17 gene encodes an enzyme involved in several critical steps of steroidogenesis. The promoter region of the CYP17 displays a single-nucleotide polymorphism, which is suspected to modulate the expression of the gene and thus may contribute in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e9044e575c9753dca85754eb9c6ffb
https://doi.org/10.1016/s0304-3835(00)00436-5

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Founder mutations in early-onset, familial and bilateral breast cancer patients from Russia

Autor: Natalia V. Mitiushkina, Alexandr V. Togo, Evgeny N. Imyanitov, Konstantin G. Buslov, Anna P. Sokolenko, Dmitry A. Voskresenskiy, Elena M. Bit-Sava, Elena V. Chekmariova, Vladimir Semiglazov, Aglaya G. Iyevleva, E. S. Shilov, Maxim E. Rozanov, Cees J. Cornelisse, Natalia Yu. Sherina, Oleg L. Chagunava, Peter Devilee

Publikováno v: Familial cancer. 6(3)

Previous studies indicate that founder mutations may play a noticeable role in breast cancer (BC) predisposition in Russia. Here we performed a systematic analysis of eight recurrent mutations in 302 BC cases (St.-Petersburg, Russia), which were sele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3ab248b5b9bbf6bcd7d9164f1721e2
https://pubmed.ncbi.nlm.nih.gov/17333477

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