Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Oleg Kuybeda"'
1
Akademický článek
Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate
Autor: Erin E. H. Tran, Kira A. Podolsky, Alberto Bartesaghi, Oleg Kuybeda, Giovanna Grandinetti, Teddy John Wohlbold, Gene S. Tan, Raffael Nachbagauer, Peter Palese, Florian Krammer, Sriram Subramaniam
Publikováno v: mBio, Vol 7, Iss 2 (2016)
ABSTRACT Influenza viruses expressing chimeric hemagglutinins (HAs) are important tools in the quest for a universal vaccine. Using cryo-electron tomography, we have determined the structures of a chimeric HA variant that comprises an H1 stalk and an
Externí odkaz: https://doaj.org/article/35be324109e04a4faa66b8868fe3368c
Zobrazit plný text záznamu
2
Akademický článek
Structural mechanism of trimeric HIV-1 envelope glycoprotein activation.
Autor: Erin E H Tran, Mario J Borgnia, Oleg Kuybeda, David M Schauder, Alberto Bartesaghi, Gabriel A Frank, Guillermo Sapiro, Jacqueline L S Milne, Sriram Subramaniam
Publikováno v: PLoS Pathogens, Vol 8, Iss 7, p e1002797 (2012)
HIV-1 infection begins with the binding of trimeric viral envelope glycoproteins (Env) to CD4 and a co-receptor on target T-cells. Understanding how these ligands influence the structure of Env is of fundamental interest for HIV vaccine development.
Externí odkaz: https://doaj.org/article/751ac1f8702e4987964ef6137c268483
Zobrazit plný text záznamu
6
Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain
Autor: Katherine Klymko, David M. Schauder, Alberto Bartesaghi, Oleg Kuybeda, Mark L. Mayer, Mario J. Borgnia, Jinjin Zhang, Sriram Subramaniam
Publikováno v: Proceedings of the National Academy of Sciences. 110:5921-5926
Glutamate receptor ion channels are membrane proteins that mediate excitatory synaptic transmission in the central nervous system of vertebrates. Insight into molecular mechanisms underlying glutamate receptor gating is limited by lack of structural
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3431391b0203c259bcec94f53cff89
https://doi.org/10.1073/pnas.1217549110
Zobrazit plný text záznamu
7
Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate
Autor: Kira A. Podolsky, Peter Palese, Giovanna Grandinetti, Oleg Kuybeda, Gene S. Tan, Florian Krammer, Teddy John Wohlbold, Erin E. H. Tran, Raffael Nachbagauer, Alberto Bartesaghi, Sriram Subramaniam
Publikováno v: mBio, Vol 7, Iss 2, p e00257-16 (2016)
mBio, Vol 7, Iss 2 (2016)
mBio
Influenza viruses expressing chimeric hemagglutinins (HAs) are important tools in the quest for a universal vaccine. Using cryo-electron tomography, we have determined the structures of a chimeric HA variant that comprises an H1 stalk and an H5 globu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523428e57ae7a28ac463debb6ea350f3
http://mbio.asm.org/cgi/content/full/7/2/e00257-16
Zobrazit plný text záznamu
8
Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging
Autor: Gabriel A. Frank, Mario J. Borgnia, Tommi A. White, Oleg Kuybeda, Sriram Subramaniam, Guillermo Sapiro, Alberto Bartesaghi
Publikováno v: Journal of Structural Biology. 178:165-176
We have previously used cryo-electron tomography combined with sub-volume averaging and classification to obtain 3D structures of macromolecular assemblies in cases where a single dominant species was present, and applied these methods to the analysi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0a671cb882d35963b78d3d4541d3fa
https://doi.org/10.1016/j.jsb.2012.01.004
Zobrazit plný text záznamu
9
Anomaly Preserving $\ell _{\scriptscriptstyle 2,\infty }$ -Optimal Dimensionality Reduction Over a Grassmann Manifold
Autor: Meir Barzohar, Oleg Kuybeda, David Malah
Publikováno v: IEEE Transactions on Signal Processing. 58:544-552
In this paper, we address the problem of redundancy reduction of high-dimensional noisy signals that may contain anomaly (rare) vectors, which we wish to preserve. Since anomaly data vectors contribute weakly to the l2-norm of the signal as compared
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fee81375ce35361bcbf523eeba0472e2
https://doi.org/10.1109/tsp.2009.2032580
Zobrazit plný text záznamu
10
Rank Estimation and Redundancy Reduction of High-Dimensional Noisy Signals With Preservation of Rare Vectors
Autor: Meir Barzohar, Oleg Kuybeda, David Malah
Publikováno v: IEEE Transactions on Signal Processing. 55:5579-5592
In this paper, we address the problem of redundancy-reduction of high-dimensional noisy signals that may contain anomaly (rare) vectors, which we wish to preserve. For example, when applying redundancy reduction techniques to hyperspectral images, it
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::819df9c0671690c891c46e8e40ac71d5
https://doi.org/10.1109/tsp.2007.901645
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje