Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Oleg Kambur"'
Autor:
Louise Grahnemo, Oleg Kambur, Leo Lahti, Pekka Jousilahti, Teemu Niiranen, Rob Knight, Veikko Salomaa, Aki S. Havulinna, Claes Ohlsson
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract The gut microbiota (GM) can regulate bone mass, but its association with incident fractures is unknown. We used Cox regression models to determine whether the GM composition is associated with incident fractures in the large FINRISK 2002 coh
Externí odkaz:
https://doaj.org/article/c6729ec7758445359a2fa2efbfaef44b
Autor:
Yulia A. Sidorova, Maxim M. Bespalov, Agnes W. Wong, Oleg Kambur, Viljami Jokinen, Tuomas O. Lilius, Ilida Suleymanova, Gunnar Karelson, Pekka V. Rauhala, Mati Karelson, Peregrine B. Osborne, Janet R. Keast, Eija A. Kalso, Mart Saarma
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Neuropathic pain caused by nerve damage is a common and severe class of chronic pain. Disease-modifying clinical therapies are needed as current treatments typically provide only symptomatic relief; show varying clinical efficacy; and most have signi
Externí odkaz:
https://doaj.org/article/386952903bfa44e9aacfe166bb459eff
Autor:
Arun Kumar Mahato, Hélder A. Santos, Eija Kalso, Hanna Viisanen, Mati Karelson, Viljami Jokinen, Oleg Kambur, Yulia Sidorova, Ulpukka Nuotio, Tuomas Lilius, Pekka Rauhala, Wei Li
Publikováno v:
Molecular Pain
The glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) alleviate symptoms of experimental neuropathy, protect and stimulate regeneration of sensory neurons in animal models of neuropathic pain, and restore their functional activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed45f369e4b59d044795f72533ab69d
http://europepmc.org/articles/PMC7440726
http://europepmc.org/articles/PMC7440726
Autor:
Eija Kalso, Tom Wilsgaard, Bendik S. Winsvold, Oleg Kambur, Mari A. Kaunisto, Audun Stubhaug, Christopher Sivert Nielsen, John-Anker Zwart
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. Variation in the P2RX7-gene, particularly single-nucleotide polymorphism rs7958311, may modulate human pain sensitivity in experimental and clinical pain phenotypes.
P2X7 is a nonselective c
P2X7 is a nonselective c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21eb46f4263e57012f7a9ec874118c44
http://hdl.handle.net/11250/2506773
http://hdl.handle.net/11250/2506773
Autor:
Ritva Jokela, Emmi Tikkanen, Aarno Palotie, Oleg Kambur, Minna Tallgren, Marjut Leidenius, Eija Kalso, Tiina Tasmuth, Reetta Sipilä, Mari A. Kaunisto, Ann-Mari Estlander, Samuli Ripatti
Publikováno v:
Anesthesiology. 119:1410-1421
Background: This article describes the methods and results of the early part (experimental pain tests and postoperative analgesia) of a study that assesses genetic and other factors related to acute pain and persistent pain after treatment of breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a9768bbb01a4e340fad04ecc64956b5
https://doi.org/10.1097/aln.0000000000000012
https://doi.org/10.1097/aln.0000000000000012
Publikováno v:
Anesthesiology. 119:1422-1433
Background: Catechol-O-methyltransferase (COMT) metabolizes catecholamines in different tissues. Polymorphisms in COMT gene can attenuate COMT activity and increase sensitivity to pain. Human studies exploring the effect of COMT polymorphisms on pain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35fc2645b995cb63ad944fd4a5eebc38
https://doi.org/10.1097/aln.0000000000000013
https://doi.org/10.1097/aln.0000000000000013
Autor:
Mati Karelson, James Thompson, Ilida Suleymanova, Jokinen, Tuomas Lilius, Eija Kalso, Yulia Sidorova, Oleg Kambur, Puusepp L, Gunnar Karelson, Maxim M. Bespalov, Mart Saarma, Pekka Rauhala
Neuropathic pain is a chronic pain condition caused by lesion or disease affecting the somatosensory system. The glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) alleviate symptoms of NP and stimulate regeneration of sensory n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8d1e8e8aaa49d1c30ed22a481752df
Autor:
Jouko Laitila, Tuomas Lilius, Eija Kalso, Pekka Rauhala, Oleg Kambur, Viljami Jokinen, Mikko Niemi
Publikováno v:
Basicclinical pharmacologytoxicology. 120(1)
Spironolactone, eplerenone, chlorothiazide and furosemide are diuretics that have been suggested to have antinociceptive properties, for example via mineralocorticoid receptor antagonism. In co-administration, diuretics might enhance the antinocicept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64aff5bc753f8445af444311d7e9c36d
https://pubmed.ncbi.nlm.nih.gov/27312359
https://pubmed.ncbi.nlm.nih.gov/27312359
Autor:
Marino Convertino, Oleg Kambur, Nikolay V. Dokholyan, Chi T. Viet, Eija Kalso, Luda Diatchenko, Jeffrey S. Wieskopf, Laura S. Stone, Pinkal Patel, Brian L. Schmidt, Jeffrey S. Mogil, William Maixner, Alexander Samoshkin, Jaclyn Marcovitz
Publikováno v:
Scientific Reports
The primary molecular target for clinically used opioids is the μ-opioid receptor (MOR). Besides the major seven-transmembrane (7TM) receptors, the MOR gene codes for alternatively spliced six-transmembrane (6TM) isoforms, the biological and clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ffc8e5874e2cfecca24a6cec6f9cef
http://europepmc.org/articles/PMC4676002
http://europepmc.org/articles/PMC4676002
Nitecapone reduces development and symptoms of neuropathic pain after spinal nerve ligation in rats1
Publikováno v:
European Journal of Pain. 15:732-740
Neuropathic pain is caused by damage or malfunctioning of the nervous system. It is fairly common and more resistant to treatment than other types of pain. Since nitecapone, an inhibitor of catechol-O-methyl-transferase (COMT), has decreased neuropat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8128633dcee6b0fdd37bdc946f81e128
https://doi.org/10.1016/j.ejpain.2010.12.001
https://doi.org/10.1016/j.ejpain.2010.12.001