Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Oleg A. Stremovskiy"'
Autor:
Victoria O. Shipunova, Polina A. Kotelnikova, Ulkar F. Aghayeva, Oleg A. Stremovskiy, Alexey A. Schulga, Maxim P. Nikitin, Sergey M. Deyev
Publikováno v:
Data in Brief, Vol 21, Iss , Pp 1659-1663 (2018)
Mms6 is a protein that plays crucial role in the biomineralization and formation of magnetosomes in magnetotactic bacteria Magnetospirillum magneticum (strain AMB-1). We developed a fusion protein of C-term part of Mms6 and Barstar (natural inhibitor
Externí odkaz:
https://doaj.org/article/0d5dcfbbee19472398a0a883d288d2c0
Autor:
Ilya A. Novikov, Polina A. Kotelnikova, Alexey A. Schulga, Oleg A. Stremovskiy, Ulkar Aghayeva, Victoria O. Shipunova, Sergey M. Deyev, Maxim P. Nikitin
Publikováno v:
Journal of Magnetism and Magnetic Materials. 469:450-455
Surface modification of nanoparticles with various biologically active molecules makes it possible to realize the huge biomedical potential of various nanoobjects. Functionally active particles are usually obtained through stabilization by polymers a
Autor:
Alexey A. Schulga, Victoria O. Shipunova, Ulkar Aghayeva, Oleg A. Stremovskiy, Sergey M. Deyev, Maxim P. Nikitin, Polina A. Kotelnikova
Publikováno v:
Data in Brief
Data in Brief, Vol 21, Iss, Pp 1659-1663 (2018)
Data in Brief, Vol 21, Iss, Pp 1659-1663 (2018)
Mms6 is a protein that plays crucial role in the biomineralization and formation of magnetosomes in magnetotactic bacteria Magnetospirillum magneticum (strain AMB-1). We developed a fusion protein of C-term part of Mms6 and Barstar (natural inhibitor
Self-assembling complexes of quantum dots and scFv antibodies for cancer cell targeting and imaging.
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48248 (2012)
Semiconductor quantum dots represent a novel class of fluorophores with unique physical and chemical properties which could enable a remarkable broadening of the current applications of fluorescent imaging and optical diagnostics. Complexes of quantu
Externí odkaz:
https://doaj.org/article/cc92d786c63a46bda46b74a4d3650c0b
Autor:
M. S. Kilyachus, Alexander M. Sapozhnikov, Anna V. Klinkova, Oleg A. Stremovskiy, Sergey M. Deyev, Elena I. Kovalenko, O. A. Shustova, Maria V. Grechikhina
Publikováno v:
Acta Naturae. 10:85-91
One important distinction between many tumor cell types and normal cells consists in the translocation of a number of intracellular proteins, in particular the 70 kDa heat shock protein (HSP70), to the surface of the plasma membrane. It has been demo
Autor:
Andrei V. Zvyagin, Ivan V. Zelepukin, Oleg A. Stremovskiy, Sergey M. Deyev, Victoria O. Shipunova, Maxim P. Nikitin, Anwar Sunna, Andrew Care
Publikováno v:
ACS Applied Materials & Interfaces. 10:17437-17447
Nanoparticle surface engineering can change its chemical identity to enable surface coupling with functional biomolecules. However, common surface coupling methods such as physical adsorption or chemical conjugation often suffer from the low coupling
Autor:
Alexey V Stepanov, Alexey A Belogurov, Natalia A Ponomarenko, Oleg A Stremovskiy, Leonid V Kozlov, Anna M Bichucher, Sergey E Dmitriev, Ivan V Smirnov, Olga G Shamborant, Dmitry S Balabashin, Lidia P Sashchenko, Alexander G Tonevitsky, Alain Friboulet, Alexander G Gabibov, Sergey M Deyev
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20991 (2011)
B cells play an important role in the pathogenesis of both systemic and organ-specific autoimmune diseases. Autoreactive B cells not only produce autoantibodies, but also are capable to efficiently present specific autoantigens to T cells. Furthermor
Externí odkaz:
https://doaj.org/article/7940345c7b77424ea6de017c94b53dff
Autor:
Oleg A. Stremovskiy, G. M. Proshkina, E. I. Shramova, D V Kiseleva, Anastasiya V. Ryabova, O N Shilova, Sergey M. Deyev
Publikováno v:
Молекулярная биология. :997-1007
We have generated and characterized HER2-specific targeted toxin based on the low-immunogenic variant of Pseudomonas exotoxin A (LoPE), in which most of the human immunodominant B-cell epitopes have been inactivated. Nonimmunoglobulin DARPin-based HE
Autor:
Victoria O. Shipunova, Oleg A. Stremovskiy, R. V. Petrov, Sergey M. Deyev, I A Novikov, Ulkar Aghayeva, Alexey A. Schulga, Maxim P. Nikitin, Polina A. Kotelnikova
Publikováno v:
Doklady Biochemistry and Biophysics. 481:198-200
A new method for obtaining biomodified magnetite nanoparticles for targeted delivery to cells was developed. The method is based on the use of the C-terminal fragment of the Mms6 protein, which is involved in the magnetite biomineralization during th
Autor:
Tatiana A. Zdobnova, E. A. Sokolova, Anastasiya V. Ryabova, Olga M Kutova, Oleg A. Stremovskiy, G. M. Proshkina, Sergey M. Deyev, Irina V. Balalaeva, Olga A. Shilova, Alexey A. Schulga
Publikováno v:
Journal of Controlled Release. 233:48-56
DARPins fused with other proteins are promising non-immunoglobulin scaffolds for specific binding to target cells. In this study HER2-specific DARPin (DARPin_9-29) was used as a tumor-targeting moiety for the delivery of a cytotoxic agent - the fragm