Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ole Scharff"'
Publikováno v:
Pancreas. 26:130-133
In some patients with severe exocrine pancreatic insufficiency, enzyme replacement therapy will not lead to clinical improvement or reduction of steatorrhea. Therefore, other mechanisms separately or in interplay with reduced enzyme secretion might b
Autor:
Birthe Foder, Ole Scharff
Publikováno v:
Cell Calcium. 16:455-466
The interplay between Ca 2+ efflux mechanisms of the plasma membrane (PM) and transient changes of the cytosolic concentration of ionized calcium ([Ca 2+ ] i ) was studied in suspensions of human neutrophils loaded with the [Ca 2+ ] i indicator, Fura
Autor:
Ole Scharff, Birthe Foder
Publikováno v:
Cell calcium. 20(1)
The ability of various cations to change the electrical potential of the plasma membrane was examined in human neutrophils by the use of the fluorescent cationic dye 3,3′-dipropylthiadicarbocyanine. When the cells were suspended in 140 mM KCI, the
Autor:
Ole Scharff, Birthe Foder
Publikováno v:
Physiological reviews. 73(3)
Autor:
Birthe Foder, Ole Scharff
Publikováno v:
Cell calcium. 13(9)
Resealed human red cell ghosts were loaded with Fura-2, ATP, Mg 2+ , and either calmodulin (CaM) or, to prevent CaM activation of the Ca 2+ pump, a synthetic peptide that antagonized endogenous CaM (an analogue of the CaM binding domain of protein ki
Autor:
Ole Scharff, Birthe Foder
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 649:367-376
The calmodulin activation of the (Ca2+ + Mg2+)-ATPase (ATP phosphohydrolase, EC 3.6.1.3) in human erythrocyte membranes was studied in the range of 1 nM to 40 microM of purified calmodulin. The apparent calmodulin-affinity of the ATPase was strongly
Autor:
Niels Jacobsen, Niels Ødum, Bo Hofmann, Birthe Foder, Erik Langhoff, K. Damgård Jacobsen, Ole Thastrup, L. P. Ryder, Ole Scharff, T. Hartvig‐Jensen, Ebbe Dickmeiss, A. Svejgaard, J Møller
Publikováno v:
Scandinavian Journal of Immunology. 30:441-447
This study was undertaken to clarify the mechanism behind the severely decreased lymphocyte proliferative response upon stimulation with mitogens and antigens seen after allogeneic bone marrow transplantation (BMT) in man. We investigated eight BMT p
Publikováno v:
Cell Calcium. 5:441-450
The A23187 induced calcium uptake in ATP depleted cells was determined at pH 6.9 in the presence of trifluoperazine (TFP, 0.30 mM), comound 48 80 (0.89 mg/ml), 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate (TMB-8, 2.13 mM) and verapamil (1.81 mM
Autor:
Birthe Foder, Ole Scharff
Publikováno v:
European Journal of Pharmacology. 159:165-173
The effect of halothane on the Ca2+-sensitive K+ channel in human erythrocytes has been investigated. The red cells were suspended in buffer-free salt solutions containing Ca2+ or 45Ca2+. The protonophore CCCP was added to bring about a rapid equilib
Autor:
Lars P. Ryder, Ebbe Dickmeiss, Erik Langhoff, Arne Svejgaard, J Møller, Peter Skinhøj, Søren Brøgger Christensen, Birthe Foder, Ole Thastrup, Klaus Damgrd Jacobsen, Bo Hofmann, Ole Scharff
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 972:257-264
The tumor-promoting sesquiterpene lactone, thapsigargin, induced a dose-dependent increase of the cytoplasmic Ca2+ concentration ([ Ca2+]i) in human lymphocytes from a resting level between 100 and 150 nM up to about 1 microM. Half-maximum response w