Investigation of racemisation of the enantiomers of glitazone drug compounds at different pH using chiral HPLC and chiral CE

Autor: Babak Jamali, Ole Nordfang, Steen Honoré Hansen, Inga Bjørnsdottir

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 46:82-87

Drug enantiomers can have biologically distinct interactions within the biological system and consequently different pharmacological or toxicological effects. Development of a better and safer drug product may be considered if one of the enantiomers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e143ce2cfdfb73760b992e419415275
https://doi.org/10.1016/j.jpba.2007.09.004

The effect of protamine sulphate on plasma tissue factor pathway inhibitor released by intravenous and subcutaneous unfractionated and low molecular weight heparin in man

Autor: Bengt Lindblad, Ulla Hedner, Ole Nordfang, David Bergqvist, Jan Holst, P. Østergaard

Publikováno v: Thrombosis Research. 86:343-348

Heparin, a negatively charged sulphated glycosaminoglycan, is clinically the most important antithrombotic drug. Heparin augments the inhibitory activity of antithrombin (AT) towards thrombin, factor Xa (FXa) and other activated clotting enzymes. Tis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1622e3dc43226dc7b980ad6af9f6c185
https://doi.org/10.1016/s0049-3848(97)00078-9

Does Glycosylation Influence the Experimental Antithrombotic Effect of a Two-Domain Tissue Factor Pathway Inhibitor?

Autor: Jan Holst, Ole Nordfang, Ulla Hedner, Bengt Lindblad, P. Østergaard

Publikováno v: Pathophysiology of Haemostasis and Thrombosis. 26:23-30

We have earlier shown that both full-length and truncated glycosylated tissue factor pathway inhibitor (TFPI) lacking the third Kunitz domain and the c-terminal region has an antithrombotic effect comparable to low-molecular-weight heparin (LMWH) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b321d2e6e6bc78dc9ae8b6a99507601
https://doi.org/10.1159/000217184

Tissue factor pathway inhibitor (TFPI) and its response to heparin in patients with spontaneous deep vein thrombosis

Autor: David Bergqvist, Eva Wedeberg, P. Østergaard, Jan Holst, Bengt Lindblad, Ulla Hedner, Ole Nordfang

Publikováno v: Thrombosis Research. 72:467-470

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9939a3ee52bea5da95e69f91e5b179
https://doi.org/10.1016/0049-3848(93)90248-m

Title Page / Table of Contents, Vol. 23, Supplement 1, 1993

Autor: Mats Hedberg, Gunilla Bengtsson-Olivecrona, A. Leizorovicz, Lars N. Jorgensen, U. Spannagel, Per Østergaard, Thomas Mätzsch, Tina Au, Ulla Hedner, Graham F. Pineo, Gary E. Raskob, Karl-Gösta Ljungström, Ole Nordfang, Jan Holst, Bengt Lindblad, Jan Frisell, P. Kujath, Qingyu Wu, Robert D. Rosenberg, Per Anders Flordal, P. Østergaard, Ulf Nyman, M.C. Haugh, Peer Wille-Jørgensen, Carlos A. Labarrere, Ulrich Abildgaard, John P. Sheehan, Evan Sadler, Gert Nielsen, Richard D. Kenagy, Page Faulk, Tetsuhito Kojima, Lars C. Borris, Iver Lausen, H. Kristensen, Russell D. Hull, Magnus Hultin, Gwendolyn J. Stewart, Anthony J. Comerota, Joan Dawes, Bertil Friberg, John A. Mclntyre, Alexander W. Clowes, Donald S. Torry, David Bergqvist, Thomas Olivecrona, Trevor W. Barrowcliffe, L.C. Petersen, Olivier Chevreuil, Jens L. Petersen, Jane Wilson, Andrew N. Nicolaides, Monika M. Clowes, Guoqing Liu, Ana Padilla, M.M. Samama, O. Nordfang, Evi Kalodiki, Mira L. Katz, Colin G. Taylor, Dawn R. Wagenknecht, Steven R. Lentz, S. Valentin, V.V. Kakkar, Klas Norrby, Nicholas W. Shworak, Göran Nylander, L. Bara, W. Habscheid, Elaine Gray, Staffan Törngren, Michael R. Lassen, Barry Halliwell, Homayoun Hashemi, Manuel Tsiang

Publikováno v: Pathophysiology of Haemostasis and Thrombosis. 23:I-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d899b8bce2705e1aa0ce01f4f5a48b68
https://doi.org/10.1159/000216902