Facing death: a multidisciplinary analysis of a Romano-Egyptian mummy mask at the Ny Carlsberg Glyptotek, Copenhagen

Autor: Tuuli Kasso, Jens Stenger, Caterina Zaggia, Gianluca Pastorelli, Max Ramsøe, Tina Ravnsborg, Ole N. Jensen, Elsa Yvanez, Chiara Spinazzi-Lucchesi, Matthew J. Collins, Cecilie Brøns

Publikováno v: Heritage Science, Vol 12, Iss 1, Pp 1-22 (2024)

Abstract Funerary masks played a crucial role in ancient Egyptian burial practices, as part of the rituals to ensure a successful afterlife. This study presents the first comprehensive analysis of a gilded mummy mask from the Roman period in Egypt fr

Externí odkaz: https://doaj.org/article/9b1c92c99d86437b84095efc0b9409d7

FLASHIda enables intelligent data acquisition for top–down proteomics to boost proteoform identification counts

Autor: Kyowon Jeong, Maša Babović, Vladimir Gorshkov, Jihyung Kim, Ole N. Jensen, Oliver Kohlbacher

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Data acquisition suitable for top-down proteomics (TDP) has the potential to significantly improve proteoform analysis. Here, the authors present FLASHIda, an intelligent online data acquisition algorithm for TDP that nearly doubles the number of pro

Externí odkaz: https://doaj.org/article/737805d51ea74ecb880a09103092dbc4

Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions

Autor: Giorgio Oliviero, Sergey Kovalchuk, Adelina Rogowska-Wrzesinska, Veit Schwämmle, Ole N Jensen

Publikováno v: eLife, Vol 11 (2022)

Temporal molecular changes in ageing mammalian organs are of relevance to disease aetiology because many age-related diseases are linked to changes in the transcriptional and epigenetic machinery that regulate gene expression. We performed quantitati

Externí odkaz: https://doaj.org/article/7ac4e6cd6db842dca686f38d0d0e3a24

On-Site Measurement of Fat and Protein Contents in Milk Using Mobile NMR Technology

Autor: Morten K. Sørensen, Nicholas M. Balsgart, Michael Beyer, Ole N. Jensen, Niels Chr. Nielsen

Publikováno v: Molecules, Vol 27, Iss 3, p 583 (2022)

Robust and easy-to-use NMR sensor technology is proposed for accurate, on-site determination of fat and protein contents in milk. The two parameters are determined using fast consecutive 1H and 35Cl low-field NMR experiments on milk samples upon the

Externí odkaz: https://doaj.org/article/1fc95f540bfe42f7a403d30b15644d02

Silencing of ceramide synthase 2 in hepatocytes modulates plasma ceramide biomarkers predictive of cardiovascular death

Autor: Christer S. Ejsing, Sandra F Gallego, Anthony H. Futerman, Richard R. Sprenger, Ole N. Jensen, Nanna Albæk, Steffen Schmidt, Marie W. Lindholm, Charlotte Øverup, Yael Pewzner-Jung, Sergey Kovalchuk, Iris D. Zelnik

Publikováno v: Mol Ther
Schmidt, S, Gallego, S F, Zelnik, I D, Kovalchuk, S, Albæk, N, Sprenger, R R, Øverup, C, Pewzner-Jung, Y, Futerman, A H, Lindholm, M W, Jensen, O N & Ejsing, C S 2022, ' Silencing of ceramide synthase 2 in hepatocytes modulates plasma ceramide biomarkers predictive of cardiovascular death ', Molecular Therapy, vol. 30, no. 4, pp. 1661-1674 . https://doi.org/10.1016/j.ymthe.2021.08.021

Emerging clinical data show that three ceramide molecules, Cer d18:1/16:0, Cer d18:1/24:1, and Cer d18:1/24:0, are biomarkers of a fatal outcome in patients with cardiovascular disease. This finding raises basic questions about their metabolic origin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b0e637383248c3671fcfcbf8c482c6
https://doi.org/10.1016/j.ymthe.2021.08.021