Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ole Kristian Hjelstuen"'
Autor:
Richard Fjellaksel, Ana Oteiza, Montserrat Martin-Armas, Patrick J. Riss, Ole Kristian Hjelstuen, Samuel Kuttner, Jørn H. Hansen, Rune Sundset
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-6 (2018)
Abstract Objectives In vivo evaluations of a gonadotropin releasing hormone-receptor single photon emission computed tomography radiotracer for non-invasive detection of gonadotropin releasing homone-receptors in brain. Results We have used a simple,
Externí odkaz:
https://doaj.org/article/3607d71fbd3c4182b734edd5904049fa
Autor:
Angel Moldes-Anaya, Terje Vasskog, Ana Oteiza, Ole Kristian Hjelstuen, Maria Montserrat Martin-Armas, Richard Fjellaksel, Patrick J. Riss, Rune Sundset, Jørn H. Hansen
The increased expression of gonadotropin releasing hormone receptor (GnRH‐R) in brain has been strongly linked to Alzheimer disease. Therefore, the development of radiolabeled imaging agents for GnRH‐R is relevant for early diagnosis of Alzheimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4acb3ddd2161fbd780b76ffb34ae887f
http://hdl.handle.net/10852/75673
http://hdl.handle.net/10852/75673
Autor:
Patrick J. Riss, Ana Oteiza, Samuel Kuttner, Rune Sundset, Jørn H. Hansen, Richard Fjellaksel, Montserrat Martin-Armas, Ole Kristian Hjelstuen
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-6 (2018)
BMC Research Notes
BMC Research Notes
Source at https://doi.org/10.1186/s13104-018-3924-2. Licensed CC BY-NC-ND 4.0. Objectives: In vivo evaluations of a gonadotropin releasing hormone-receptor single photon emission computed tomography radiotracer for non-invasive detection of gonadotro
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 78:307-313
In [(18)F]fluoride chemistry, the minute amounts of radioactivity taking part in a radiolabeling reaction are easily outnumbered by other reactants. Surface areas become comparably larger and more influential than in standard fluorine chemistry, whil
Publikováno v:
Applied Radiation and Isotopes. 69:289-294
Leachables of borosilicate glassware and silica-based anion exchange columns (QMAs) may influence nucleophilic substitution with [(18)F]fluoride ([(18)F]F(-)). Aluminum, boron and silicon, all constituents of borosilicate glass, were found as water s
Autor:
Dag Erlend Olberg, Joseph M Arukwe, Ole Kristian Hjelstuen, Alan Cuthbertson, Alexandr Kristian, Magne Solbakken, Skjalg Bruheim, Hong Qu
Publikováno v:
Bioconjugate Chemistry. 21:2297-2304
We have recently reported a new N-methylaminooxy-based prosthetic group for the site-selective introduction of ¹⁸F-fluorine under mild acidic aqueous conditions into model peptides functionalized with a Michael acceptor moiety. To further investig
Autor:
Damir Dugalic, Richard Fjellaksel, Rune Sundset, Taye B. Demissie, Patrick J. Riss, Ole Kristian Hjelstuen, Jørn H. Hansen
Publikováno v:
Journal of Physical Organic Chemistry. 31:e3835
This is the peer reviewed version of the following article: Fjellaksel, R., Dugalic, D., Demissie, T.B., Riss, P., Hjelstuen, O.-K., Sundset, R. & Hansen, J.H. (2018). An Acylation-Finkelstein Approach to Radioiodination of Bioactives: The Role of Am
Autor:
Joseph Arukwe, Alan Cuthbertson, Hege Karlsen, Magne Solbakken, Ole Kristian Hjelstuen, Dag Erlend Olberg
Publikováno v:
Bioconjugate Chemistry. 19:1301-1308
Efficient methodologies for the radiolabeling of peptides with [(18)F]fluoride are a prerequisite to enabling commercialization of peptide-containing radiotracers for positron emission tomography (PET) imaging. It was the purpose of this study to inv
Autor:
Dag Erlend, Olberg, Alan, Cuthbertson, Magne, Solbakken, Joseph M, Arukwe, Hong, Qu, Alexandr, Kristian, Skjalg, Bruheim, Ole Kristian, Hjelstuen
Publikováno v:
Bioconjugate chemistry. 21(12)
We have recently reported a new N-methylaminooxy-based prosthetic group for the site-selective introduction of ¹⁸F-fluorine under mild acidic aqueous conditions into model peptides functionalized with a Michael acceptor moiety. To further investig
Autor:
Joseph Arukwe, Dag Erlend Olberg, Magne Solbakken, Alan Cuthbertson, Grete Mørk Kindberg, David Grace, Ole Kristian Hjelstuen
Publikováno v:
Journal of medicinal chemistry. 53(4)
The labeling of biomolecules for positron emission tomography (PET) with no-carrier-added fluorine-18 is almost exclusively accomplished using prosthetic groups in a two step procedure. The inherent complexity of the process renders full automation a