Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ole Kjærulff"'
Autor:
Rita C. Andersen, Jan H. Schmidt, Joscha Rombach, Matthew D. Lycas, Nikolaj R. Christensen, Viktor K. Lund, Donnie S. Stapleton, Signe S. Pedersen, Mathias A. Olsen, Mikkel Stoklund, Gith Noes-Holt, Tommas T.E. Nielsen, Mark P. Keller, Anna M. Jansen, Rasmus Herlo, Massimo Pietropaolo, Jens B. Simonsen, Ole Kjærulff, Birgitte Holst, Alan D. Attie, Ulrik Gether, Kenneth L. Madsen
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 5 (2022)
Bin/amphiphysin/Rvs (BAR) domains are positively charged crescent-shaped modules that mediate curvature of negatively charged lipid membranes during remodeling processes. The BAR domain proteins PICK1, ICA69, and the arfaptins have recently been demo
Externí odkaz:
https://doaj.org/article/283f087eadbe4c509ab194ae13855604
Autor:
Freja Herborg, Kathrine L. Jensen, Sasha Tolstoy, Natascha V. Arends, Leonie P. Posselt, Aparna Shekar, Jenny I. Aguilar, Viktor K. Lund, Kevin Erreger, Mattias Rickhag, Matthew D. Lycas, Markus N. Lonsdale, Troels Rahbek-Clemmensen, Andreas T. Sørensen, Amy H. Newman, Annemette Løkkegaard, Ole Kjærulff, Thomas Werge, for the iPSYCH researchers, Lisbeth B. Møller, Heinrich J.G. Matthies, Aurelio Galli, Lena E. Hjermind, Ulrik Gether
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Dysfunctional dopaminergic neurotransmission is central to movement disorders and mental diseases. The dopamine transporter (DAT) regulates extracellular dopamine levels, but the genetic and mechanistic link between DAT function and dopamine-related
Externí odkaz:
https://doaj.org/article/0e76e431d1f8444ba28610dba3786a03
Autor:
Viktor Karlovich Lund, Matthew Domenic Lycas, Anders Schack, Rita Chan Andersen, Ulrik Gether, Ole Kjaerulff
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108973- (2021)
Summary: Fast axonal transport of neuropeptide-containing dense core vesicles (DCVs), endolysosomal organelles, and presynaptic components is critical for maintaining neuronal functionality. How the transport of DCVs is orchestrated remains an import
Externí odkaz:
https://doaj.org/article/037826ddd050416a9d7e03037c4eec03
Autor:
Birgitte Holst, Kenneth L Madsen, Anna M Jansen, Chunyu Jin, Mattias Rickhag, Viktor K Lund, Morten Jensen, Vikram Bhatia, Gunnar Sørensen, Andreas N Madsen, Zhichao Xue, Siri K Møller, David Woldbye, Klaus Qvortrup, Richard Huganir, Dimitrios Stamou, Ole Kjærulff, Ulrik Gether
Publikováno v:
PLoS Biology, Vol 11, Iss 4, p e1001542 (2013)
Secretory vesicles in endocrine cells store hormones such as growth hormone (GH) and insulin before their release into the bloodstream. The molecular mechanisms governing budding of immature secretory vesicles from the trans-Golgi network (TGN) and t
Externí odkaz:
https://doaj.org/article/1b1e37beba824678913f7f38cf8eb86b
Autor:
Anita G Jung, Christina Labarrera, Anna M Jansen, Klaus Qvortrup, Klemens Wild, Ole Kjaerulff
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9492 (2010)
BACKGROUND: Endophilin is a cytoplasmic protein with an important function in clathrin-dependent endocytosis at synapses and elsewhere. Endophilin has a BAR (Bin/Amphiphysin/Rvs-homology) domain, which is implicated in the sensing and induction of me
Externí odkaz:
https://doaj.org/article/a7236c045f7a4a83b46e71dab74a7159
Autor:
Anita G. Jung, Christina Labarrera, Anna M. Jansen, Klaus Qvortrup, Klemens Wild, Ole Kjaerulff
Publikováno v:
PLoS ONE, Vol 5, Iss 3 (2010)
Externí odkaz:
https://doaj.org/article/9482c0f5c878400c908eb282ecf2b0e2
Autor:
Kevin Erreger, Mattias Rickhag, Leonie P. Posselt, Aparna Shekar, Aurelio Galli, Troels Rahbek-Clemmensen, Markus Nowak Lonsdale, Sasha Tolstoy, Annemette Løkkegaard, Amy Hauck Newman, Natascha V. Arends, Andreas T. Sørensen, Thomas Werge, Viktor K. Lund, Lisbeth Birk Møller, Jenny I. Aguilar, Ulrik Gether, Kathrine L. Jensen, Lena Elisabeth Hjermind, Matthew D. Lycas, Ole Kjaerulff, Heinrich J.G. Matthies, Freja Herborg
Publikováno v:
JCI Insight
Herborg, F, Jensen, K L, Tolstoy, S, Arends, N, Posselt, L P, Shekar, A, Aguilar, J, Lund, V K, Erreger, K, Rickhag, M, Lycas, M D, Lonsdale, M N, Rahbek-Clemmensen, T, Sorensen, A T, Newman, A H, Lokkegaard, A, Kjaerulff, O, Werge, T, Moller, L B, Matthies, H J G, Galli, A, Hjermind, L E, Gether, U & IPSYCH Researchers 2021, ' Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease ', JCI insight, vol. 6, no. 18, 151496 . https://doi.org/10.1172/jci.insight.151496
Herborg, F, Jensen, K L, Tolstoy, S, Arends, N, Posselt, L P, Shekar, A, Aguilar, J, Lund, V K, Erreger, K, Rickhag, M, Lycas, M D, Lonsdale, M N, Rahbek-Clemmensen, T, Sorensen, A T, Newman, A H, Lokkegaard, A, Kjaerulff, O, Werge, T, Moller, L B, Matthies, H J G, Galli, A, Hjermind, L E, Gether, U & IPSYCH Researchers 2021, ' Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease ', JCI insight, vol. 6, no. 18, 151496 . https://doi.org/10.1172/jci.insight.151496
Dysfunctional dopaminergic neurotransmission is central to movement disorders and mental diseases. The dopamine transporter (DAT) regulates extracellular dopamine levels, but the genetic and mechanistic link between DAT function and dopamine-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca6cf7f70e973bb64f7b6009b997c20
https://pubmed.ncbi.nlm.nih.gov/34375312
https://pubmed.ncbi.nlm.nih.gov/34375312
Autor:
Ulrik Gether, A. Loekkegaard, Andreas T. Sørensen, Natascha V. Arends, Aparna Shekar, Aurelio Galli, Freja Herborg, L. B. Moeller, Kenneth Jensen, Markus Nowak Lonsdale, Viktor K. Lund, Mattias Rickhag, Kevin Erreger, Amy Hauck Newman, Thomas Werge, Matthew D. Lycas, Ole Kjaerulff, S. Tolstoy, Jenny I. Aguilar, L. P. Posselt, Troels Rahbek-Clemmensen, Heinrich J.G. Matthies, Lena Elisabeth Hjermind
Dopaminergic dysfunction is central to movement disorders and mental diseases. The dopamine transporter (DAT) is essential for the regulation of extracellular dopamine but the genetic and mechanistic link between DAT function and dopamine-related pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af0f6e9d581a10325c3f789babc51d7b
https://doi.org/10.1101/2020.10.12.336461
https://doi.org/10.1101/2020.10.12.336461
Autor:
Matthew D. Lycas, Joscha Rombach, Birgitte Holst, Ole Kjaerulff, Nikolaj R. Christensen, Jan Hendrik Schmidt, Gith Noes-Holt, Mark P. Keller, Rasmus Herlo, Anna M. Jansen, Alan D. Attie, Donnie S. Stapleton, Mikkel Stoklund, Viktor K. Lund, Rita C. Andersen, Kenneth L. Madsen, Ulrik Gether
SummaryBin/amphiphysin/Rvs (BAR) domains are positively charged crescent-shaped modules that shape negatively charged curved lipid membranes during membrane remodeling processes. The BAR domain proteins ICA69, PICK1 and arfaptins have recently been d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3907a97ccaaa64eba8d931c6e91ee753
https://doi.org/10.1101/2020.10.05.325951
https://doi.org/10.1101/2020.10.05.325951
Autor:
Ulrik Gether, Anders Schack, Matthew D. Lycas, Ole Kjaerulff, Viktor K. Lund, Rita C. Andersen
Publikováno v:
Lund, V K, Lycas, M D, Schack, A, Andersen, R C, Gether, U & Kjaerulff, O 2021, ' Rab2 drives axonal transport of dense core vesicles and lysosomal organelles ', Cell Reports, vol. 35, no. 2, 108973 . https://doi.org/10.1016/j.celrep.2021.108973
Cell Reports, Vol 35, Iss 2, Pp 108973-(2021)
Cell Reports, Vol 35, Iss 2, Pp 108973-(2021)
Summary: Fast axonal transport of neuropeptide-containing dense core vesicles (DCVs), endolysosomal organelles, and presynaptic components is critical for maintaining neuronal functionality. How the transport of DCVs is orchestrated remains an import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215da4125209d671a0ba2e59d966d926
https://doi.org/10.1101/2020.06.03.131672
https://doi.org/10.1101/2020.06.03.131672