Cohort profile:The Funen Diabetes Database - A population-based cohort of patients with diabetes in Denmark

Autor: Henning Beck-Nielsen, Kasper Adelborg, Lars Pedersen, Reimar W. Thomsen, Jens Sundbøll, Péter Szentkúti, Jan Erik Henriksen, Ole Hother-Nielsen, Henrik Toft Sørensen

Publikováno v: Adelborg, K, Szentkúti, P, Henriksen, J E, Thomsen, R W, Pedersen, L, Sundbøll, J, Sørensen, H T, Hother-Nielsen, O & Beck-Nielsen, H 2020, ' Cohort profile : The Funen Diabetes Database-A population-based cohort of patients with diabetes in Denmark ', BMJ Open, vol. 10, no. 4, 035492 . https://doi.org/10.1136/bmjopen-2019-035492
BMJ Open
Adelborg, K, Szentkúti, P, Henriksen, J E, Thomsen, R W, Pedersen, L, Sundbøll, J, Sørensen, H T, Hother-Nielsen, O & Beck-Nielsen, H 2020, ' Cohort profile : the Funen Diabetes Database-a population-based cohort of patients with diabetes in Denmark ', BMJ Open, vol. 10, no. 4, e035492 . https://doi.org/10.1136/bmjopen-2019-035492

PurposeDetailed population-based data are essential to understanding the epidemiology of diabetes and its clinical course. This article describes the Funen Diabetes Database (FDDB). The purpose of the FDDB was to serve as a shared electronic medical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9331014bb012ad7bdddc7e553e94044
https://findresearcher.sdu.dk:8443/ws/files/170856796/e035492.full.pdf

Glucose effectiveness and insulin sensitivity measurements derived from the non-insulin-assisted minimal model and the clamp techniques are concordant

Autor: Henning Beck-Nielsen, Frank P. Alford, Glenn M. Ward, Jan Erik Henriksen, Raymond C. Boston, Peter Thye-Rønn, Ole Hother-Nielsen, Klaus Levin, Christian Rantzau

Publikováno v: Henriksen, J E, Alford, F, Ward, G, Thye-Rønn, P, Levin, K, Hother-Nielsen, O, Rantzau, C, Boston, R & Beck-Nielsen, H 2010, ' Glucose effectiveness and insulin sensitivity measurements derived from the non-insulin-assisted minimal model and the clamp techniques are concordant ', Diabetes-Metabolism: Research and Reviews (Print Edition), vol. 26, no. 7, pp. 569-78 . https://doi.org/10.1002/dmrr.1127

Background We investigated the concordance between glucose effectiveness (SG) and insulin sensitivity (SI), derived from the unmodified dynamic non-insulin-assisted intravenous glucose tolerance test (IVGTT) implemented by SGMM and SIMM; simulation a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e29883572d0b054dd59acb91d4276eb
https://doi.org/10.1002/dmrr.1127

Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers

Autor: Kurt Højlund, Kim Brøsen, Per Damkier, Henning Beck-Nielsen, Mette Marie Hougaard Christensen, Tore Bjerregaard Stage, Ole Hother-Nielsen

Publikováno v: Christensen, M M H, Højlund, K, Hother-Nielsen, O, Stage, T B, Damkier, P, Beck-Nielsen, H & Brøsen, K 2015, ' Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers ', European Journal of Clinical Pharmacology, vol. 71, no. 6, pp. 691-697 . https://doi.org/10.1007/s00228-015-1853-8

PURPOSE: The aim of the study was to determine the steady-state pharmacokinetics of metformin in healthy volunteers with different numbers of reduced-function alleles in the organic cation transporter 1 gene (OCT1).METHODS: The study was conducted as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbda2836038bdbcbcb6036e85001563a
https://portal.findresearcher.sdu.dk/da/publications/6858ae7f-41a4-4121-b34e-ad1d1e9bc78e

Effects of Troglitazone in Young First-Degree Relatives of Patients With Type 2 Diabetes

Autor: Jan Erik Henriksen, Henning Beck-Nielsen, Ole Hother-Nielsen, Klaus Levin

Publikováno v: Diabetes Care. 27:148-154

OBJECTIVE—Insulin resistance is a key characteristic of first-degree relatives of patients with type 2 diabetes. We therefore treated young, glucose-tolerant relatives with the insulin action enhancer troglitazone in order to determine the effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dce043d6c0e8846443e1399569af291
https://doi.org/10.2337/diacare.27.1.148

Is hepatic glucose production increased in type 2 diabetes mellitus?

Autor: Ole Hother-Nielsen, Peter Staehr, Henning Beck-Nielsen

Publikováno v: Current Diabetes Reports. 2:231-236

Based on recent studies, including our own, using what we consider to be an appropriate technique to estimate rates of hepatic glucose production (HGP), this article can be summarized as follows: 1) HGP in the overnight fasted state is near normal in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07af64ca739c53e2bc48048fa2899720
https://doi.org/10.1007/s11892-002-0088-0