Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Ole D. Mjøs"'
Publikováno v:
Regulatory Peptides. 174:90-97
Corticotrophin-releasing factor receptor 2β (CRFR2β) is expressed in the myocardium. In the present study we explore whether acute treatment with the neuropeptide corticotrophin-releasing factor (CRF) could induce cytoprotection against a lethal is
Publikováno v:
Acta Pathologica Microbiologica Scandinavica Series A :Pathology. :115-124
The aim of the present study was to determine whether induction of ischaemic heart failure by micro-embolization leads to only a single episode of myocardial injury or whether it sets up a vicious cycle of progressive myocardial damage. Acute left ve
Publikováno v:
Acta Medica Scandinavica. 203:21-26
Autor:
Ole D. Mjøs
Publikováno v:
Acta Medica Scandinavica. 199:29-34
Publikováno v:
Journal of Molecular and Cellular Cardiology. 37:43-50
The purpose of this study was to determine if elevated myocardial glycogen content could obviate Ca(2+) overload and subsequent myocardial injury in the setting of low oxygen and diminished exogenous substrate supplies. Isolated harp seal cardiomyocy
Publikováno v:
Biochemical and Biophysical Research Communications. 315:160-165
Insulin administration attenuates cardiac ischemia-reperfusion apoptosis via activation of Akt-mediated cell-survival signaling. As p70s6 kinase is a cognate Akt-mediated phosphorylation target we evaluated whether p70s6 kinase activation is a functi
Publikováno v:
Cardiovascular Drugs and Therapy. 14:31-39
Fuel substrate utilization is highly regulated during cardiac development and with the onset of cardiac hypertrophy. Glucose and lactate are the predominant fuel substrates utilized during cardiac development. Postnatally, a switch occurs so that fat
Publikováno v:
Cardiovascular Drugs and Therapy. 14:615-623
Coronary reperfusion improves ventricular function and survival after infarction, but the metabolic conditions at this time may not be optimal to protect the heart. The objective of this study was to evaluate if metabolic support with glucose-insulin
Publikováno v:
Acta physiologica (Oxford, England). 195(2)
Aim: To compare the possible role of Akt and mammalian target of rapamycin (mTOR) in mediating cardioprotection against ischaemia under three different conditions: (1) During ischaemic preconditioning (IPC), (2) when insulin was given as a pretreatme
Publikováno v:
Perfusion. 5:169-180
The production of oxygen free radicals (OFR) by leucocytes was evaluated ex vivo by chemiluminescence (CL) before, during and after routine coronary artery bypass surgery (group A, n=11). The possibility of leucocyte trapping in the coronary circulat