Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Oldřich Lapčík"'
Autor:
Lucie Fojtíková, Anna Šuláková, Martina Blažková, Barbora Holubová, Martin Kuchař, Petra Mikšátková, Oldřich Lapčík, Ladislav Fukal
Publikováno v:
Toxicology Reports, Vol 5, Iss , Pp 65-75 (2018)
In recent years, the use of synthetic cannabinoids (SCs) as drugs of abuse has greatly increased. SCs are associated with a risk of severe poisoning or even death. Therefore, more rapid, cost effective and reliable methods are needed, especially for
Externí odkaz:
https://doaj.org/article/c6611bd255524468ad04977d13264afa
Publikováno v:
Sensors, Vol 22, Iss 1, p 4 (2021)
Anabolic-androgenic steroids (AASs), a group of compounds frequently misused by athletes and, unfortunately, also by the general population, have lately attracted global attention; thus, significant demands for more precise, facile, and rapid AAS det
Externí odkaz:
https://doaj.org/article/0a949b259a474dc8b076a510f76431e6
Autor:
Barbora Holubová, Pavla Kubešová, Lukáš Huml, Miroslav Vlach, Oldřich Lapčík, Michal Jurášek, Ladislav Fukal
Publikováno v:
Foods, Vol 10, Iss 4, p 741 (2021)
In recent years, the undeclared presence of various anabolic androgenic steroids (AAS) in commercial supplements has been confirmed. This fact can be a potential threat to all athletes using these supplements, and therefore, there is of increased int
Externí odkaz:
https://doaj.org/article/5fd1032ee0f340c6883987bb0bd93bc2
Autor:
Barbora HOLUBOVÁ, Sandra GÖSELOVÁ, Ludmila ŠEVČÍKOVÁ, Miroslav VLACH, Martina BLAŽKOVÁ, Oldřich LAPČÍK, Ladislav FUKAL
Publikováno v:
Czech Journal of Food Sciences, Vol 31, Iss 5, Pp 514-519 (2013)
An enzyme immunoassay (ELISA) and an immunochromatographic strip were designed for a rapid detection of nortestosterone in dietary supplements. Two polyclonal antibodies and two types of nortestosterone-protein coating conjugates were tested to devel
Externí odkaz:
https://doaj.org/article/502364e1a572450b8c215aef07a3f220
Autor:
Lucie Sosvorová, Petra Lanková, Marie Bičíková, Elena A. Prokudina, Nawaf Al Maharik, Oldřich Lapčík
Publikováno v:
Czech Journal of Food Sciences, Vol 29, Iss 1, Pp 57-64 (2011)
The popularity of phytoestrogen food supplements of plant origin steadily increases. They are used to solve the problems related to the climacterium. Their efficiency depends on woman's capability to metabolise the active components - isoflavonoids.
Externí odkaz:
https://doaj.org/article/a76422355c774b62bf3c523b881bcac9
Autor:
Pavel Drašar, Petr Bartůněk, Vladimíra Pavlíčková, Eliška Staňková, Zdeňka Rottnerová, Tomáš Ruml, Michal Jurášek, Kamil Záruba, Marketa Simkova, Jan Fähnrich, Silvie Rimpelová, David Sedlák, Oldřich Lapčík, David Kodr
Publikováno v:
Journal of Materials Chemistry B. 7:5465-5477
Photodynamic therapy has become a feasible direction for the treatment of both malignant and non-malignant diseases. It has been in the spotlight since FDA regulatory approval was granted to several photosensitizers worldwide. Nevertheless, there are
Immunochemical techniques for anabolic androgenic steroid: matrix effects study for food supplements
Autor:
Petra Mikšátková, Martin Kuchař, Ladislav Fukal, Oldřich Lapčík, Ludmila Karamonová, Barbora Holubová
Publikováno v:
European Food Research and Technology. 245:1011-1019
Anabolic androgenic steroid contaminations in food supplements are common, and their consumption may lead to positive doping results. One of such anabolic steroid is mesterolone selected as an analyte for the present study. Some contaminated suppleme
Autor:
Barbora Holubová, Petra Mikšátková, Lucie Fojtíková, Martin Kuchař, Ladislav Fukal, Oldřich Lapčík, Martina Blažková, Anna Šuláková
Publikováno v:
Toxicology Reports, Vol 5, Iss, Pp 65-75 (2018)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • A hapten with [(morpholin-4-yl)alkyl]indole moiety is used in the detection of JWH-200. • The hapten is synthesized via Rosenmund–von Braun and Friedel-Crafts reactions. • ELISA and LFIA are developed and
Highlights • A hapten with [(morpholin-4-yl)alkyl]indole moiety is used in the detection of JWH-200. • The hapten is synthesized via Rosenmund–von Braun and Friedel-Crafts reactions. • ELISA and LFIA are developed and
Publikováno v:
Vnitřní lékařství. 63:598-603
An important potential consequence of the anabolic steroid misuse is hypogonadotropic hypogonadism due to the inhibition of pituitary secretion of gonadotropins. By the symptoms as testicular atrophy, spermatogenic and fertility disturbances or dysfu
Autor:
Petra Mikšátková, Pavel Drašar, Michal Jurášek, Barbora Holubová, Sandra Göselová, Ladislav Fukal, Eva Vyšatová, Martin Kuchař, Oldřich Lapčík
Publikováno v:
Drug Testing and Analysis. 9:553-560
Avidin-biotin technology was used for the implementation of an enzyme-linked immunosorbent assay (AB-ELISA) as a sensitive method for the detection of anabolic androgenic steroids (AAS) present in dietary supplements. Using click chemistry, novel hap