Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Olavi R, Pelkonen"'
Publikováno v:
Frontiers in Pharmacology, Vol 1 (2010)
Liquid chromatography-mass spectrometry (LC/MS) with generic gradient elution for a large number of chemically different compounds is a common approach in drug development, used to acquire a large amount of data in a short time frame for drug candida
Externí odkaz:
https://doaj.org/article/5d7b104c8e164552bc435f534e53ff33
Autor:
Jos G, Bessems, George, Loizou, Kannan, Krishnan, Harvey J, Clewell, Camilla, Bernasconi, Frederic, Bois, Sandra, Coecke, Eva-Maria, Collnot, Walter, Diembeck, Lucian Romeo, Farcal, Liesbeth, Geraets, Ursula, Gundert-Remy, Nynke, Kramer, Gabriele, Küsters, Sofia B, Leite, Olavi R, Pelkonen, Klaus, Schröder, Emanuela, Testai, Iwona, Wilk-Zasadna, José-Manuel, Zaldívar-Comenges
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 68(1)
Information on toxicokinetics is critical for animal-free human risk assessment. Human external exposure must be translated into human tissue doses and compared with in vitro actual cell exposure associated to effects (in vitro-in vivo comparison). D