Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy

Autor: Thomas Lass Klitgaard, Olav Lilleholt Schjørring, Frederik Mølgaard Nielsen, Christian Sylvest Meyhoff, Marija Barbateskovic, Jørn Wetterslev, Anders Perner, Bodil Steen Rasmussen

Publikováno v: Journal of Intensive Care, Vol 9, Iss 1, Pp 1-5 (2021)

Abstract In a recent paper, Chen et al. report the findings of a systematic review with meta-analysis concerning conservative versus conventional oxygen therapy for critically ill patients. We wish to commend the authors for their interest in the mat

Externí odkaz: https://doaj.org/article/a3b442b788e949edba3b6c97ca848e61

Lower versus higher oxygenation targets in hypoxaemic ICU patients after cardiac arrest

Autor: Elena Crescioli, Thomas Lass Klitgaard, Anders Perner, Olav Lilleholt Schjørring, Bodil Steen Rasmussen

Publikováno v: Crescioli, E, Lass Klitgaard, T, Perner, A, Lilleholt Schjørring, O & Steen Rasmussen, B 2023, ' Lower versus higher oxygenation targets in hypoxaemic ICU patients after cardiac arrest ', Resuscitation, vol. 188, 109838 . https://doi.org/10.1016/j.resuscitation.2023.109838
Crescioli, E, Lass Klitgaard, T, Perner, A, Lilleholt Schjørring, O & Steen Rasmussen, B 2023, ' Lower versus higher oxygenation targets in hypoxaemic ICU patients after cardiac arrest ', Resuscitation . https://doi.org/10.1016/j.resuscitation.2023.109838

Aim: To investigate the effects of lower versus higher oxygenation targets in adult intensive care unit (ICU) patients with hypoxaemic respiratory failure after cardiac arrest. Methods: Subgroup analysis of the international Handling Oxygenation Targ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ba0f72158860c2775bf148e238de09
https://vbn.aau.dk/da/publications/50806a80-05f4-4e1b-acb8-6163d682dabc

Association between days alive without life support/out of hospital and health‐related quality of life

Autor: Anders Granholm, Olav Lilleholt Schjørring, Aksel Karl Georg Jensen, Benjamin Skov Kaas‐Hansen, Marie Warrer Munch, Thomas Lass Klitgaard, Elena Crescioli, Maj‐Brit Nørregaard Kjær, Thomas Strøm, Theis Lange, Anders Perner, Bodil Steen Rasmussen, Morten Hylander Møller

Publikováno v: Granholm, A, Schjørring, O L, Jensen, A K G, Kaas-Hansen, B S, Munch, M W, Klitgaard, T L, Crescioli, E, Kjær, M-B N, Strøm, T, Lange, T, Perner, A, Rasmussen, B S & Møller, M H 2023, ' Association between days alive without life support/out of hospital and health-related quality of life ', Acta Anaesthesiologica Scandinavica, vol. 67, no. 6, pp. 762-771 . https://doi.org/10.1111/aas.14231
Granholm, A, Schjorring, O L, Jensen, A K G, Kaas-Hansen, B S, Munch, M W, Klitgaard, T L, Crescioli, E, Kjaer, M-B N, Strom, T, Lange, T, Perner, A, Rasmussen, B S & Moller, M H 2023, ' Association between days alive without life support/out of hospital and health-related quality of life ', Acta Anaesthesiologica Scandinavica, vol. 67, no. 6, pp. 762-771 . https://doi.org/10.1111/aas.14231
Granholm, A, Schjørring, O L, Jensen, A K G, Kaas-Hansen, B S, Munch, M W, Klitgaard, T L, Crescioli, E, Kjær, M-B N, Strøm, T, Lange, T, Perner, A, Rasmussen, B S & Møller, M H 2023, ' Association between days alive without life support/out of hospital and health-related quality of life ', Acta Anaesthesiologica Scandinavica . https://doi.org/10.1111/aas.14231

Background: Trials in critically ill patients increasingly focus on days alive without life support (DAWOLS) or days alive out of hospital (DAOOH) and health-related quality of life (HRQoL). DAWOLS and DAOOH convey more information than mortality and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adbcf9fff34a6d94a048842145adbe7f
https://doi.org/10.1111/aas.14231

An overview of methodological considerations regarding adaptive stopping, arm dropping and randomisation in clinical trials

Autor: Anders Granholm, Benjamin Skov Kaas-Hansen, Theis Lange, Olav Lilleholt Schjørring, Lars W. Andersen, Anders Perner, Aksel Karl Georg Jensen, Morten Hylander Møller

Publikováno v: Granholm, A, Kaas-Hansen, B S, Lange, T, Schjørring, O L, Andersen, L W, Perner, A, Jensen, A K G & Møller, M H 2023, ' An overview of methodological considerations regarding adaptive stopping, arm dropping and randomisation in clinical trials ', Journal of Clinical Epidemiology, vol. 153, pp. 45-54 . https://doi.org/10.1016/j.jclinepi.2022.11.002
Granholm, A, Kaas-Hansen, B S, Lange, T, Schjørring, O L, Andersen, L W, Perner, A, Jensen, A K G & Møller, M H 2023, ' An overview of methodological considerations regarding adaptive stopping, arm dropping, and randomization in clinical trials ', Journal of Clinical Epidemiology, vol. 153, pp. 45-54 . https://doi.org/10.1016/j.jclinepi.2022.11.002

OBJECTIVE: Adaptive features may increase flexibility and efficiency of clinical trials, and improve participants' chances of being allocated to better interventions. Our objective is to provide thorough guidance on key methodological considerations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f4186c5c26e209574530a6e0e32744
https://curis.ku.dk/ws/files/328430785/Fulltext.pdf

Clinical diversity in trials from a Cochrane systematic review of targeted oxygen therapy in the intensive care unit – protocol for a systematic evaluation

Autor: Thomas Lass Klitgaard, Bodil Steen Rasmussen, Olav Lilleholt Schjørring, Frederik Mølgaard Nielsen, Elena Crescioli, Jørn Wetterslev, Marija Barbateskovic

Introduction Oxygen therapy is used extensively in the intensive care unit (ICU) to prevent or treat hypoxaemia. However, the current evidence is insufficient to determine the optimum dosage of supplementary oxygen, and conducted meta-analyses of ran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24952ddbff7db2e1f2ff59d5675b6d80