Výsledky vyhledávání - "Olav L. M. Bijvoet"

Application of an in vitro model and a clinical protocol in the assessment of the potency of a new bisphosphonate

Autor: Klaas Hoekman, Pieter Vermeij, Olav L. M. Bijvoet, Socrates E. Papapoulos, Clemens W.G.M. Löwik

Publikováno v: Journal of Bone and Mineral Research. 4:775-781

The development of new bisphosphonates for clinical use requires congruence between the results of basic and clinical investigations. We have previously shown that this can be achieved with the use of an in vitro coculture mouse metacarpal resorption

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b535ecbaa774af9a9327c224da6bb831
https://doi.org/10.1002/jbmr.5650040518

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Migration and phenotypic transformation of osteoclast precursors into mature osteoclasts: The effect of a bisphosphonate

Autor: L. van der Wee-Pals, Olav L. M. Bijvoet, H. Bloys van Treslong-de Groot, Clemens W.G.M. Löwik, G. van der Pluijm

Publikováno v: Journal of Bone and Mineral Research. 3:185-192

Osteoclast-devoid bone explants were cultured together with embryonic liver as a source of osteoclast precursors, but separated from each other by a filter. Cells migrated through the filter toward the calcified matrix and acquired the characteristic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f978a74ad210e95e0191a3352bd06d4c
https://doi.org/10.1002/jbmr.5650030210

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Automated comparison of dual-photon absorptiometric studies of the lumbar spine

Autor: J. A. K. Blokland, Socrates E. Papapoulos, Ernest K. J. Pauwels, Luis F. Verheij, Olav L. M. Bijvoet

Publikováno v: Journal of Bone and Mineral Research. 6:575-581

An automated image comparison procedure was developed to optimize the precision of bone mineral density measurements by dual-photon absorptiometry. Changed acquisition conditions cause differences between two images to be compared. Alignment of one i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee392fc05221b5ef03d98c610836556
https://doi.org/10.1002/jbmr.5650060608

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Improved treatment of paget's disease with dimethylaminohydroxypropylidene bisphosphonate

Autor: Socrates E. Papapoulos, Aeilko H. Zwinderman, Olav L. M. Bijvoet, Dave H. Schweitzer, Pieter Vermeij

Publikováno v: Journal of Bone and Mineral Research. 8:175-182

A group of 89 patients with Paget's disease of bone were treated with different intravenous or oral doses of the nitrogen-containing bisphosphonate dimethylaminohydroxypropylidene bisphosphonate (dimethyl-APD). Biochemical remission was obtained in 8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602faf25e21fa389c8d484b856dec4ea
https://doi.org/10.1002/jbmr.5650080208

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Rickets before the discovery of vitamin D

Autor: J. L. H. O'riordan, Olav L. M. Bijvoet

Publikováno v: BoneKEy Reports. 3

The story of rickets leading to the discovery of vitamin D is an extraordinary tale, spread over many centuries and involving some remarkable characters with much speculation and a few mysteries, before reaching an exciting climax. It would be wrong

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72c00c06c48632211a3b2e27fc73204
https://doi.org/10.1038/bonekey.2013.212

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The effect of tissue type plasminogen activator (tPA) on osteoclastic resorption in embryonic mouse long bone explants: a possible role for the growth factor domain of tPA

Autor: Klaas Hoekman, Jan H. Verheijen, Socrates E. Papapoulos, Olav L. M. Bijvoet, Clemens W.G.M. Löwik, Marianne van de Ruit

Publikováno v: Bone and Mineral. 17:1-13

Summary Osteoblasts produce proteolytic enzymes and their production is regulated by osteotropic agents. It has been suggested that these proteases play a role in bone resorption by removing the superficial collagenous layer from the bone matrix and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f510189e2d90503d324d76419c28061f
https://doi.org/10.1016/0169-6009(92)90706-j

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Regulation of the production of plasminogen activators by bone resorption enhancing and inhibiting factors in three types of osteoblast-like cells

Autor: Jan H. Verheijen, Klaas Hoekman, Olav L. M. Bijvoet, Clemens W.G.M. Löwik, Socrates E. Papapoulos, Marianne van de Ruit

Publikováno v: Bone and Mineral. 14:189-204

Production of proteolytic enzymes by osteoblasts is considered to be important for the initiation of osteoclastic bone resorption. We examined the production of tissue-type (tPA) and urokinase-type plasminogen activator (uPA) activity by three types

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ac5462741d57065cb29ffe14f0ff7d
https://doi.org/10.1016/0169-6009(91)90022-r

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The effect of supportive pamidronate treatment on aspects of quality of life of patients with advanced breast cancer

Autor: F.J. Cleton, Angelique T.M. van Holten-Verzantvoort, Birgit van den Bos, Beatrix van Emmerik, Frits S.A.M. van Dam, Olav L. M. Bijvoet, Neil K. Aaronson, Jo Hermans, Aeilko H. Zwinderman

Publikováno v: European Journal of Cancer and Clinical Oncology. 27:544-549

Selective aspects of quality of life during supportive pamidronate (APD) treatment were assessed in breast cancer patients with osteolytic metastases. 144 patients were randomised to a pamidronate group (n = 76) or a control group (n = 68). A questio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59f396dc785278b51da3653c77cec88
https://doi.org/10.1016/0277-5379(91)90212-v

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Palliative pamidronate treatment in patients with bone metastases from breast cancer

Autor: Socrates E. Papapoulos, Harm Sleeboom, H.M. Kroon, L.V.A.M. Beex, J.P. Neijt, G. Blijham, Olav L. M. Bijvoet, Jo Hermans, F.J. Cleton, A.T.M. van Holten-Verzantvoort

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 11(3)

PURPOSE An open, randomized study was performed to assess the effects of supportive pamidronate treatment on morbidity from bone metastases in breast cancer patients. PATIENTS AND METHODS Eighty-one pamidronate patients and 80 control patients were m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328cc4b2d997d26e7b0a33038c8fdde6
https://pubmed.ncbi.nlm.nih.gov/7680374

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