Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Olav Kaalhus"'
Publikováno v:
Molecular Pharmaceutics. 6:255-264
Mammalian target of rapamycin (mTOR) is a regulator of cell growth and proliferation and its activity is altered in many human cancers. The main objective of this study was to evaluate in vitro and in vivo targeting of mTOR by photodynamic therapy (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de3c26ff61cca191fb43ca56e28dc8c
https://doi.org/10.1021/mp800156e
https://doi.org/10.1021/mp800156e
Publikováno v:
Photochemistry and Photobiology. 76:452-456
Significant amounts of protoporphyrin IX (PpIX) are formed after 6 min of topical application of 5-aminolevulinic acid (ALA) and its hexylester derivative, whereas PpIX is formed after 10 min of topical application of ALA-methylester derivative in no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5234eacfacc1ef83145c2f649a8e56f3
https://doi.org/10.1562/0031-8655(2002)0760452teoaop2.0.co2
https://doi.org/10.1562/0031-8655(2002)0760452teoaop2.0.co2
Publikováno v:
British Journal of Cancer
Photochemical internalisation (PCI) is a technique for releasing biologically active macromolecules from endocytic vesicles by light activation of a photosensitiser localised in the same vesicles of targeted cells. This study investigated the PCI of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41c5fcada47b8e2aaaf1253220f17b0
https://doi.org/10.1038/sj.bjc.6602600
https://doi.org/10.1038/sj.bjc.6602600
Publikováno v:
Radiation Research. 163:289-295
Ultraviolet irradiation of cells can induce a state of genomic instability that can persist for several cell generations after irradiation. However, questions regarding the time course of formation, relative abundance for different types of ultraviol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656800b6440b65425d22c632f7ed3ce3
https://doi.org/10.1667/rr3305
https://doi.org/10.1667/rr3305
Publikováno v:
Cytometry. :182-188
Background Clonogenic assays are used frequently to measure the cell killing and mutagenic effects of radiation and other agents. Clonogenic assays carried out manually are tedious and time-consuming and involve a significant element of subjectivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbca2f17830f226d2f4e33d0e5dc578
https://doi.org/10.1002/cyto.a.20038
https://doi.org/10.1002/cyto.a.20038
Noninvasive fluorescence excitation spectroscopy during application of 5-aminolevulinic acid in vivo
Publikováno v:
Photochemical & Photobiological Sciences. 1:745-748
The fluorescence of PpIX induced by topical application of 5-aminolevulinic acid (ALA) in normal mouse skin was studied noninvasively by means of a fibre optic probe. The fluorescence excitation spectrum of PpIX exhibits five distinct peaks at around
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f98c2f2f7e0154145a8b2a2bad26a2c
https://doi.org/10.1039/b203459j
https://doi.org/10.1039/b203459j
Autor:
Hans H. Lien, Heidi Lyng, Ingeborg Taksdal, Einar K. Rofstad, Olav Kaalhus, Ann O. Vorren, Kolbein Sundfør
Publikováno v:
Journal of Magnetic Resonance Imaging. 14:750-756
Increased knowledge of the physiological basis behind the signal enhancement in tumors during dynamic contrast-enhanced magnetic resonance (MR) imaging may be useful in development of predictive assays based on this technique. In the present work, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0c2767c4417030ed6fbae03769c86ff
https://doi.org/10.1002/jmri.10016
https://doi.org/10.1002/jmri.10016
Autor:
Ingeborg Taksdal, Hans H. Lien, Olav Kaalhus, Heidi Lyng, Kolbein Sundfør, Einar K. Rofstad, Ann O. Vorren
Publikováno v:
International Journal of Cancer. 96:182-190
Knowledge of the intratumor heterogeneity in blood perfusion may lead to increased understanding of tumor response to treatment. In the present work, absolute perfusion values, in units of ml/g.min, were determined in 20 tumor subregions of patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02400f62c250a804c119511dd8ce9f8e
https://doi.org/10.1002/ijc.1019
https://doi.org/10.1002/ijc.1019
Publikováno v:
Magnetic Resonance Imaging. 18:997-1002
The perfusion in tumors shows substantial spatial heterogeneity compared to that in normal tissues. The aim of the present study was to evaluate the intratumor heterogeneity in perfusion in tumors of two amelanotic human melanoma xenograft lines, A-0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac534a350da519f1ec4a2448c6e680e
https://doi.org/10.1016/s0730-725x(00)00188-0
https://doi.org/10.1016/s0730-725x(00)00188-0
Publikováno v:
Experimental Cell Research. 252:449-463
12-O-Tetradecanoylphorbol-13-acetate (TPA) caused strong suppression of gap junctional intercellular communication, altered phosphorylation status of the gap junction protein, connexin43, and disappearance of immunorecognizible connexin43-containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842425d1638b1bc04bc3dcf3d1afb589
https://doi.org/10.1006/excr.1999.4650
https://doi.org/10.1006/excr.1999.4650