Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Olav Dajani"'
Autor:
Michael S. Yule, Joshua Thompson, Khachonphat Leesahatsawat, Mariana S. Sousa, Stefan D. Anker, Jann Arends, Trude R. Balstad, Leo R. Brown, Asta Bye, Olav Dajani, Marie Fallon, Marianne J. Hjermstad, Gunnhild Jakobsen, James McDonald, Josh McGovern, Eric J. Roeland, Judith Sayers, Richard J.E. Skipworth, Inger O. Ottestad, Iain Philips, Melanie R. Simpson, Tora S. Solheim, Ola Magne Vagnildhaug, Donald McMillan, Barry J.A. Laird, Ross D. Dolan, the Cancer Cachexia Endpoints Working Group
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 853-867 (2024)
Abstract Regulatory agencies require evidence that endpoints correlate with clinical benefit before they can be used to approve drugs. Biomarkers are often considered surrogate endpoints. In cancer cachexia trials, the measurement of biomarkers featu
Externí odkaz:
https://doaj.org/article/b91388b921c54b20be4595865bc85c5f
Autor:
Leo R. Brown, Mariana S. Sousa, Michael S. Yule, Vickie E. Baracos, Donald C. McMillan, Jann Arends, Trude R. Balstad, Asta Bye, Olav Dajani, Ross D. Dolan, Marie T. Fallon, Christine Greil, Marianne J. Hjermstad, Gunnhild Jakobsen, Matthew Maddocks, James McDonald, Inger O. Ottestad, Iain Phillips, Judith Sayers, Melanie R. Simpson, Ola M. Vagnildhaug, Tora S. Solheim, Barry J.A. Laird, Richard J.E. Skipworth, the Cancer Cachexia Endpoints Working Group
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 816-852 (2024)
Abstract Significant variation exists in the outcomes used in cancer cachexia trials, including measures of body composition, which are often selected as primary or secondary endpoints. To date, there has been no review of the most commonly selected
Externí odkaz:
https://doaj.org/article/97fbbcfba63e4845963cae99e9a6f886
Autor:
James McDonald, Judith Sayers, Stefan D. Anker, Jann Arends, Trude Rakel Balstad, Vickie Baracos, Leo Brown, Asta Bye, Olav Dajani, Ross Dolan, Marie T. Fallon, Eilidh Fraser, Christine Griel, Aleksandra Grzyb, Marianne Hjermstad, Mariam Jamal‐Hanjani, Gunnhild Jakobsen, Stein Kaasa, Donald McMillan, Matthew Maddocks, Iain Philips, Inger O. Ottestad, Kieran F. Reid, Mariana S. Sousa, Melanie R. Simpson, Ola Magne Vagnildhaug, Richard J. E. Skipworth, Tora S. Solheim, Barry J. A. Laird, the Cancer Cachexia Endpoints Working Group
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 5, Pp 1932-1948 (2023)
Abstract In cancer cachexia trials, measures of physical function are commonly used as endpoints. For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be needed alongside other measures. However, it is not clear
Externí odkaz:
https://doaj.org/article/631dce5bbeae444e8aa791e121b8775f
Autor:
Elias David Lundereng, Andréa Aparecida Gonçalves Nes, Heidi Holmen, Anette Winger, Hilde Thygesen, Nina Jøranson, Christine Råheim Borge, Olav Dajani, Kari L Mariussen, Simen A Steindal
Publikováno v:
Journal of Medical Internet Research, Vol 25, p e43429 (2023)
BackgroundTelehealth seems feasible for use in home-based palliative care (HBPC). It may improve access to health care professionals (HCPs) at patients’ homes, reduce hospital admissions, enhance patients’ feelings of security and safety, and inc
Externí odkaz:
https://doaj.org/article/29d1b58076a74b96b644fde923ab94a8
Autor:
Marianne Jensen Hjermstad, Nina Aass, Sigve Andersen, Cinzia Brunelli, Olav Dajani, Herish Garresori, Hanne Hamre, Ellinor C. Haukland, Mats Holmberg, Frode Jordal, Hilde Krogstad, Tonje Lundeby, Erik Torbjørn Løhre, Svein Mjåland, Arve Nordbø, Ørnulf Paulsen, Erik Schistad Staff, Torunn Wester, Stein Kaasa, Jon Håvard Loge
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background Several publications have addressed the need for a systematic integration of oncological care focused on the tumor and palliative care (PC) focused on the patient with cancer. The exponential increase in anticancer treatments and
Externí odkaz:
https://doaj.org/article/1a4a08695fec4e0784a3592419d7ba86
Autor:
Elias David Lundereng, Andrea Aparecida Goncalves Nes, Heidi Holmen, Anette Winger, Hilde Thygesen, Nina Jøranson, Chrstine Råheim Borge, Weiqin Chen, Olav Dajani, Kari L Mariussen, Simen A Steindal
Publikováno v:
JMIR Research Protocols, Vol 10, Iss 10, p e33305 (2021)
BackgroundTelehealth seems feasible for use in home-based palliative care. However, acceptance among health care professionals (HCPs) is essential for the successful delivery of telehealth in practice. No scoping review has mapped the experiences and
Externí odkaz:
https://doaj.org/article/12c98a5f0ca44b1bb0b15243061b5fe0
Autor:
Sarina A. Piha-Paul, Alessandra Tosolini, Ann Swift, Ruixue Wang, Jonathan D. Cheng, Olav Dajani, Antoine Hollebecque, Pamela N. Munster, Guillem Argilés, Shilpa Gupta
Purpose: The PI3K/Akt/mTOR signaling pathway is aberrantly activated in many cancers. Combining ridaforolimus, an mTOR inhibitor, with MK-2206, an Akt inhibitor, may more completely block the PI3K pathway and inhibit tumor growth.Experimental Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0384ca382c611a5c9521773f79fb7af1
https://doi.org/10.1158/1078-0432.c.6524507.v1
https://doi.org/10.1158/1078-0432.c.6524507.v1
Autor:
Sarina A. Piha-Paul, Alessandra Tosolini, Ann Swift, Ruixue Wang, Jonathan D. Cheng, Olav Dajani, Antoine Hollebecque, Pamela N. Munster, Guillem Argilés, Shilpa Gupta
Supplemental Results. Using a custom designed Affymetrix microarray, we describe a RAS pathway activation signature consisting of 147 gene transcripts identified by combining data from fresh-frozen tissue samples, cell lines, and the literature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d24ef1e81ed23da54932cac27272343
https://doi.org/10.1158/1078-0432.22460483.v1
https://doi.org/10.1158/1078-0432.22460483.v1
Autor:
Elias David Lundereng, Andréa Aparecida Gonçalves Nes, Heidi Holmen, Anette Winger, Hilde Thygesen, Nina Jøranson, Christine Råheim Borge, Olav Dajani, Kari L Mariussen, Simen A Steindal
BACKGROUND Telehealth seems feasible for use in home-based palliative care (HBPC). It may improve access to health care professionals (HCPs) at patients’ homes, reduce hospital admissions, enhance patients’ feelings of security and safety, and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1774cda505c6120cf6a0f81885d5ac45
https://doi.org/10.2196/preprints.43429
https://doi.org/10.2196/preprints.43429
Autor:
Olav Dajani, Elin H. Kure, Per Pfeiffer, Bengt Glimelius, K. L.G. Spindler, Halfdan Sorbye, Ole Christian Lingjærde, Niels Pallisgaard, Tormod Kyrre Guren, Julian Hamfjord, Kjell Magne Tveit
Publikováno v:
International Journal of Cancer. 149:1385-1397
Detection of tumour-specific circulating cell-free DNA in plasma (ctDNA) fails in a significant number of cases depending on the clinical context. The primary aim was to investigate clinicopathological factors associated with detection of ctDNA in pa