Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Olatunji B Alese"'
Autor:
Gregory B Lesinski, Christina Wu, Mehmet Akce, Brian Olson, Maria Diab, Batoul Farran, Jeffrey M Switchenko, Manali Rupji, Sandra Kang, Lana Khalil, Amanda Ruggieri-Joyce, Walid L Shaib, Olatunji B Alese, Bassel F El-Rayes
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Preclinical studies showed metformin reduces exhaustion of tumor-infiltrating lymphocytes and potentiates programmed cell death protein-1 (PD-1) blockade. We hypothesized that metformin with nivolumab would elicit potent antitumor and immu
Externí odkaz:
https://doaj.org/article/2bc4352546204629923aab3d10545a4e
Autor:
Yufen Lin, Laura S Porter, Wonshik Chee, Olatunji B Alese, Kimberly A Curseen, Melinda K Higgins, Laurel Northouse, Canhua Xiao
Publikováno v:
JMIR Research Protocols, Vol 12, p e48499 (2023)
BackgroundPatients with colorectal cancer (CRC) receiving chemotherapy often experience psychoneurological symptoms (PNS; ie, fatigue, depression, anxiety, sleep disturbance, pain, and cognitive dysfunction) that negatively impact both patients’ an
Externí odkaz:
https://doaj.org/article/172a0e1cd80549389f3175047c8b6e30
Autor:
Olatunji B. Alese, Wei Zhou, Renjian Jiang, Katerina Zakka, Zhonglu Huang, Chimuanya Okoli, Walid L. Shaib, Mehmet Akce, Maria Diab, Christina Wu, Bassel F. El-Rayes
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundPathologic staging is crucial in colorectal cancer (CRC). Unlike the majority of solid tumors, the current staging model does not use tumor size as a criterion. We evaluated the predictive and prognostic impact of primary tumor size on all
Externí odkaz:
https://doaj.org/article/245fe7f0a67440899eb8a532d113a8a5
Autor:
Kenneth H. Yu, Andrew E. Hendifar, Olatunji B. Alese, Amber Draper, Maen Abdelrahim, Ethan Burns, Gazala Khan, Paul Cockrum, Rachel H. Bhak, Catherine Nguyen, Maral DerSarkissian, Mei Sheng Duh, Nathan Bahary
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe NAPOLI-1 trial demonstrated that liposomal irinotecan in combination with fluorouracil (5-FU) and leucovorin (LV) prolonged survival with a manageable safety profile in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) p
Externí odkaz:
https://doaj.org/article/43a57f71459e47a9b5b2ba864581164f
Autor:
Mehmet Asim Bilen, Julie M. Shabto, Dylan J. Martini, Yuan Liu, Colleen Lewis, Hannah Collins, Mehmet Akce, Haydn Kissick, Bradley C. Carthon, Walid L. Shaib, Olatunji B. Alese, Conor E. Steuer, Christina Wu, David H. Lawson, Ragini Kudchadkar, Viraj A. Master, Bassel El-Rayes, Suresh S. Ramalingam, Taofeek K. Owonikoko, R. Donald Harvey
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Selecting the appropriate patients to receive immunotherapy (IO) remains a challenge due to the lack of optimal biomarkers. The presence of liver metastases has been implicated as a poor prognostic factor in patients with metastat
Externí odkaz:
https://doaj.org/article/3a89538b1b6f4594bd638b17c5ad5f05
Autor:
Mehmet Akce, Katerina Zakka, Renjian Jiang, Shayla Williamson, Olatunji B. Alese, Walid L. Shaib, Christina Wu, Madhusmita Behera, Bassel F. El-Rayes
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundTumor sidedness as a prognostic factor in advanced stage colon cancer (CC) is well established. The impact of tumor sidedness on the clinical outcomes of stage II and III CC has not been well studied.MethodsThe National Cancer Database (NCD
Externí odkaz:
https://doaj.org/article/a21ef40733be4c92bef3c918b73a697f
Autor:
Mehmet Akce, Katerina Zakka, McKenna Penley, Renjian Jiang, Lana Khalil, Olatunji B. Alese, Walid L. Shaib, Christina Wu, Madhusmita Behera, Bassel F. El-Rayes
Publikováno v:
Cancer Treatment and Research Communications, Vol 27, Iss , Pp 100329- (2021)
Background: Clinico-pathological high-risk features are frequently utilized in adjuvant chemotherapy (AC) decisions in stage II colorectal cancer and their utility in stage II appendiceal adenocarcinoma (AA) is not established. The aim of this study
Externí odkaz:
https://doaj.org/article/5728cf035af04df68adae6562aaf6b08
Autor:
Amber Draper, Emily H. Jung, Yichun Cao, Rami P. Atallah, Jeffrey Switchenko, Sujata Kane, Jessica Guadagno, Aaron T. Jones, Edith Brutcher, Olatunji B. Alese
Publikováno v:
Oncology. 101:213-223
Introduction: Checkpoint inhibitors (CPI) have significantly improved survival among patients with various cancer types. Prior studies have shown a correlation between immune cell infiltration and poorly differentiated cancers. This study evaluated t
Autor:
Dae Won Kim, Young-chul Kim, Bence P. Kovari, Vincent Chung, Olatunji B. Alese, Bassel F. El-Rayes, Daneng Li, Wungki Park, Richard D. Kim
Publikováno v:
European Journal of Cancer. 176:171-180
Our previous phase II study demonstrated that nivolumab provides modest but durable clinical efficacy in patients with refractory biliary tract cancer, suggesting the significant clinical benefit of nivolumab in selected patients and the necessity of
Autor:
Raghavan Chinnadurai, Rafaela Scandolara, Olatunji B. Alese, Dalia Arafat, Deepak Ravindranathan, Alton B. Farris, Bassel F. El-Rayes, Greg Gibson
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Mechanisms of dysfunctional T cell immunity in Hepatocellular Carcinoma (HCC) need to be well defined. B7 family molecules provide both co-stimulatory and co-inhibitory signals to T cells while tryptophan degrading enzymes like Indoleamine 2,3 dioxyg
Externí odkaz:
https://doaj.org/article/89533a239bca4b98bdf1b0d636892287