Výsledky vyhledávání - "Olatunde Owoeye"

Kolaviron suppresses dysfunctional reproductive axis associated with multi-walled carbon nanotubes exposure in male rats

Autor: Ikenna C. Maduako, Ifeoluwa O. Awogbindin, Olatunde Owoeye, Anita K. Patlolla, Isaac A. Adedara, Ebenezer O. Farombi, Akinola O. Ajeleti, Solomon E. Owumi

Publikováno v: Environmental Science and Pollution Research. 28:354-364

Reproductive toxicity associated with excessive exposure to multi-walled carbon nanotubes (MWCNTs), which are commonly used in medicine as valuable drug delivery systems, is well documented. Kolaviron, a bioflavonoid isolated from Garcinia kola seeds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40b31aebd36b38e5f07610436231839a
https://doi.org/10.1007/s11356-020-10324-y

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Lead-induced oxidative stress in postnatal developing cerebellum of Wistar rats: role of aqueous extract of Cucumis sativus Linn and vitamin C

Autor: Innocent O Imosemi, Adu Y Olawande, Olatunde Owoeye, Malomo AO

Publikováno v: MOJ Anatomy & Physiology. 7:104-113

Lead (Pb) is one of the most abundant heavy metal whose toxicity causes environmental and health problems, with the brain being highly sensitive to lead toxicity. There is limited literature regarding the protection of the developing brain against le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fe5cca9f9fbb9a27f07522053a54676
https://doi.org/10.15406/mojap.2020.07.00299

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Kolaviron ameliorates behavioural deficit and injury to striatal dopaminergic terminals via modulation of oxidative burden, DJ-1 depletion and CD45R+ cells infiltration in MPTP-model of Parkinson’s disease

Autor: Edirin R. Izomoh, Victoria O. Abah, Ebenezer O. Farombi, Ibukunoluwa O. Ezekiel, Ifeoluwa O. Awogbindin, Olatunde Owoeye

Publikováno v: Metabolic Brain Disease. 35:933-946

Parkinson’s disease (PD) is the second most common neurodegenerative disease. Currently, the precise pathogenic detail of PD is not entirely clear and first line therapeutics fail to attenuate the progress of the disease. In this study, we examined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::821cedb976d0081d519a959b69328b51
https://doi.org/10.1007/s11011-020-00578-3

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Kolaviron via anti-inflammatory and redox regulatory mechanisms abates multi-walled carbon nanotubes-induced neurobehavioral deficits in rats

Autor: Solomon E. Owumi, Akinola O. Ajeleti, Ikenna C. Maduako, Ifeoluwa O. Awogbindin, Isaac A. Adedara, Olatunde Owoeye, Anita K. Patlolla, Ebenezer O. Farombi

Publikováno v: Psychopharmacology. 237:1027-1040

Exposure to multi-walled carbon nanotubes (MWCNTs) reportedly elicits neurotoxic effects. Kolaviron is a phytochemical with several pharmacological effects namely anti-oxidant, anti-inflammatory, and anti-genotoxic activities. The present study evalu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a54f5126c227a3cdeb89728bdaba862
https://doi.org/10.1007/s00213-019-05432-8

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Influence of furan and lead co-exposure at environmentally relevant concentrations on neurobehavioral performance, redox-regulatory system and apoptotic responses in rats

Autor: Solomon E, Owumi, Isaac A, Adedara, Moses T, Otunla, Olatunde, Owoeye

Publikováno v: Environmental Toxicology and Pharmacology. 97:104011

Furan and lead are contaminants of global concern due to the potential public health threat associated with their exposure. Herein, the neurobehavioral performance, biochemical effects and histological alterations associated with co-exposure to furan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f997ae5817e45401ee0b7d7ec697c9
https://doi.org/10.1016/j.etap.2022.104011

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Protective effects of Celosia argentea Linn. Vitamin E and dexamethasone on radiation-induced damage on the developing rat cerebellum

Autor: I. O. Imosemi, Adelofolarin Obanishola Malomo, Love Chioma Kanu, Olatunde Owoeye

Publikováno v: Anatomy Journal of Africa; Vol 8, No 2 (2019); 1647-1661

The potential neuroprotective effect of aqueous extract of Celosia argentea Linn (AECA), Vitamin E (Vit E) and Dexamethasone (Dexa) on radiation-induced damage on the developing rat cerebellum was studied. Forty-two female rats weighing between 147 g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ee1c7443d3c6e975075052c65e33cd
https://doi.org/10.4314/aja.v8i2.190407

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Jobelyn® ameliorates neurological deficits in rats with ischemic stroke through inhibition of release of pro-inflammatory cytokines and NF-κB signaling pathway

Autor: Benneth Ben-Azu, Solomon Umukoro, Osarume Omorogbe, Olatunde Owoeye, Abayomi M. Ajayi, Ejiroghene E. Oghwere, Olajuwon Okubena

Publikováno v: Pathophysiology. 26:77-88

The effects of Jobelyn® (JB) on neurological deficits and biochemical alterations associated with ischemic stroke induced by bilateral common carotid artery occlusion (BCCAO) in rats were investigated in this study. Male Wistar rats were divided int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2006612b1fc689abe1c63b451650a54f
https://doi.org/10.1016/j.pathophys.2018.10.002

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Diphenyl diselenide abrogates brain oxidative injury and neurobehavioural deficits associated with pesticide chlorpyrifos exposure in rats

Autor: Babajide O. Ajayi, Isaac A. Adedara, João Rocha, Ebenezer O. Farombi, Ifeoluwa O. Awogbindin, Olatunde Owoeye

Publikováno v: Chemico-Biological Interactions. 296:105-116

Exposure to pesticide chlorpyrifos (CPF) is associated with neurodevelopmental toxicity both in humans and animals. Diphenyl diselenide (DPDS) is a simple synthetic organoselenium well reported to possess antioxidant, anti-inflammatory and neuroprote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2f588a1f6f80369d5c87c66e6b1fe1
https://doi.org/10.1016/j.cbi.2018.09.016

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Ethanol exacerbates manganese‐induced oxidative/nitrosative stress, pro‐inflammatory cytokines, nuclear factor‐κB activation, and apoptosis induction in rat cerebellar cortex

Autor: Isaac A. Adedara, Matthew O. Wegwu, Ebenezer O. Farombi, Amos O. Abolaji, Benjamin A. Amadi, Olatunde Owoeye, Kpobari W. Nkpaa

Publikováno v: Journal of Biochemical and Molecular Toxicology. 35

Manganese (Mn) exposure is causing public health concerns as well as heavy alcohol consumption. This study investigates the mechanisms of neurotoxicity associated with Mn and ethanol (EtOH) exposure in the rat cerebellar cortex. Experimental animals

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101ddb35717bfbe03be529ecece2782c
https://doi.org/10.1002/jbt.22681

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Protective role of protocatechuic acid in carbon tetrachloride-induced oxidative stress via modulation of proinflammatory cytokines levels in brain and liver of Wistar rats

Autor: Emmanuel N. Ekpo, Olorunfemi R. Molehin, Olatunde Owoeye, Esther O. Olatoye, Folake O. Asejeje, Anne A. Adeyanju

Publikováno v: Journal of basic and clinical physiology and pharmacologyReferences. 33(2)

Objectives Protocatechuic acid (PCA) possesses numerous pharmacological activities, including antioxidative and anti-inflammatory activities. This study seeks to investigate its underlying mechanism of action in the liver and brain toxicity induced b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71565b826422795ff9ed805174a15f27
https://pubmed.ncbi.nlm.nih.gov/33735948

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