Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Olamide B. Adelusi"'
Autor:
Hartmut Jaeschke, Olamide B. Adelusi, Jephte Y. Akakpo, Nga T. Nguyen, Giselle Sanchez-Guerrero, David S. Umbaugh, Wen-Xing Ding, Anup Ramachandran
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3740-3755 (2021)
Acetaminophen (APAP) is a widely used analgesic and antipyretic drug, which is safe at therapeutic doses but can cause severe liver injury and even liver failure after overdoses. The mouse model of APAP hepatotoxicity recapitulates closely the human
Externí odkaz:
https://doaj.org/article/bd69267488f147738d37afb49958d353
Autor:
Nga T. Nguyen, David S. Umbaugh, Sawyer Smith, Olamide B. Adelusi, Giselle Sanchez-Guerrero, Anup Ramachandran, Hartmut Jaeschke
Publikováno v:
Archives of Toxicology. 97:1397-1412
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::422eae9dc9a3c2ad9d43474cd0387f63
https://doi.org/10.1007/s00204-023-03478-4
https://doi.org/10.1007/s00204-023-03478-4
Autor:
Nga T Nguyen, David S Umbaugh, Eileen L Huang, Olamide B Adelusi, Giselle Sanchez Guerrero, Anup Ramachandran, Hartmut Jaeschke
Publikováno v:
Toxicol Sci
Acetaminophen (APAP) overdose is the main cause of acute liver failure in Western countries. The mechanism of APAP hepatotoxicity is associated with centrilobular necrosis which initiates infiltration of neutrophils, monocytes, and other leukocytes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52742d4d3f6f9e4971eac5d30062edb6
https://doi.org/10.1093/toxsci/kfac057
https://doi.org/10.1093/toxsci/kfac057
Publikováno v:
Toxicol Appl Pharmacol
Acetaminophen (APAP) hepatotoxicity, a leading cause of acute liver failure in western countries, is characterized by mitochondrial superoxide and peroxynitrite formation. However, the role of iron, especially as facilitator of lipid peroxidation (LP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb47eea55e9e85eb32b7068e5216f88
https://europepmc.org/articles/PMC9843742/
https://europepmc.org/articles/PMC9843742/
Autor:
Wen-Xing Ding, Hartmut Jaeschke, David S Umbaugh, Olamide B. Adelusi, Giselle Sanchez-Guerrero, Nga T. Nguyen, Jephte Y. Akakpo, Anup Ramachandran
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3740-3755 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3740-3755 (2021)
Acetaminophen (APAP) is a widely used analgesic and antipyretic drug, which is safe at therapeutic doses but can cause severe liver injury and even liver failure after overdoses. The mouse model of APAP hepatotoxicity recapitulates closely the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde30b76b24a28a9236a78a6ec2b0a30
https://pubmed.ncbi.nlm.nih.gov/35024303
https://pubmed.ncbi.nlm.nih.gov/35024303
Publikováno v:
Gene Expr
Acetaminophen (APAP) hepatotoxicity is the most frequent cause of acute liver failure in the US. The mechanisms of APAP-induced liver injury have been under extensive investigations for decades, and many key events of this necrotic cell death are kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8397afc58e4886e9760e5a329288a2a
https://europepmc.org/articles/PMC8201653/
https://europepmc.org/articles/PMC8201653/