Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Olaia Martínez-Iglesias"'
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1306 (2023)
Neurodegeneration, characterized by the progressive deterioration of neurons and glial cells, is a feature of Alzheimer’s disease (AD). The present study aims to demonstrate that the onset and early progression of neurodegenerative processes in tra
Externí odkaz:
https://doaj.org/article/8f84be91768040059a8208f13be7f1cf
Autor:
Olaia Martínez-Iglesias, Vinogran Naidoo, Iván Carrera, Juan Carlos Carril, Natalia Cacabelos, Ramón Cacabelos
Publikováno v:
Biology, Vol 12, Iss 9, p 1156 (2023)
Pharmacogenetics and DNA methylation influence therapeutic outcomes and provide insights into potential therapeutic targets for brain-related disorders. To understand the effect of genetic polymorphisms on drug response and disease risk, we analyzed
Externí odkaz:
https://doaj.org/article/394262e825fd48948614e827b8efe2c0
Autor:
Olaia Martínez-Iglesias, Vinogran Naidoo, Lola Corzo, Iván Carrera, Silvia Seoane, Susana Rodríguez, Margarita Alcaraz, Adriana Muñiz, Natalia Cacabelos, Ramón Cacabelos
Publikováno v:
Biology, Vol 12, Iss 6, p 806 (2023)
Dyslipidemia is a significant risk factor for cardiovascular disease and stroke. Our recent findings showed that RCI-1502, a bioproduct derived from the muscle of the European S. pilchardus, has lipid-lowering effects in the liver and heart in high-f
Externí odkaz:
https://doaj.org/article/dc7edb197bd94ddfae5726eb68e5bca3
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 216 (2023)
Neurodegenerative disorders (NDDs) are major health issues in Western countries. Despite significant efforts, no effective therapeutics for NDDs exist. Several drugs that target epigenetic mechanisms (epidrugs) have been recently developed for the tr
Externí odkaz:
https://doaj.org/article/01aa3e6b755345bcaaab9a9048fd89c8
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2447 (2022)
Alzheimer’s disease (AD), the most common cause of dementia, causes irreversible memory loss and cognitive deficits. Current AD drugs do not significantly improve cognitive function or cure the disease. Novel bioproducts are promising options for t
Externí odkaz:
https://doaj.org/article/050cd66424584882b2bcf86c5768e880
Autor:
Ramón Cacabelos, Vinogran Naidoo, Olaia Martínez-Iglesias, Lola Corzo, Natalia Cacabelos, Rocío Pego, Juan C. Carril
Publikováno v:
Life, Vol 12, Iss 3, p 460 (2022)
Alzheimer’s disease (AD) is a priority health problem with a high cost to society and a large consumption of medical and social resources. The management of AD patients is complex and multidisciplinary. Over 90% of patients suffer from concomitant
Externí odkaz:
https://doaj.org/article/4857e8b2184348ddb68d2a0e563cf036
Publikováno v:
Life, Vol 12, Iss 1, p 97 (2022)
Novel and effective chemotherapeutic agents are needed to improve cancer treatment. Epidrugs are currently used for cancer therapy but also exhibit toxicity. Targeting the epigenetic apparatus with bioproducts may aid cancer prevention and treatment.
Externí odkaz:
https://doaj.org/article/f0672a71d84f4c8cb9e6f2fb72379577
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6428 (2009)
BACKGROUND:Whereas there is increasing evidence that loss of expression and/or function of the thyroid hormone receptors (TRs) could result in a selective advantage for tumor development, the relationship between thyroid hormone levels and human canc
Externí odkaz:
https://doaj.org/article/f7d949e60509455cbe73f416cec0d942
Autor:
Ramón Cacabelos, Juan C Carril, Lola Corzo, Rocío Pego, Natalia Cacabelos, Margarita Alcaraz, Adriana Muñiz, Olaia Martínez-Iglesias, Vinogran Naidoo
Publikováno v:
Pharmacogenomics. 24:27-57
Anxiety and depression coexist with cognitive impairment in Alzheimer's disease along with other concomitant disorders (>60%), which require multipurpose treatments. Polypharmaceutical regimens cause drug–drug interactions and adverse drug reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93211d49ba4cf53e5fb36ce8ca4c5c58
https://doi.org/10.2217/pgs-2022-0137
https://doi.org/10.2217/pgs-2022-0137
Autor:
Cacabelos, Olaia Martínez-Iglesias, Vinogran Naidoo, Lola Corzo, Iván Carrera, Silvia Seoane, Susana Rodríguez, Margarita Alcaraz, Adriana Muñiz, Natalia Cacabelos, Ramón
Publikováno v:
Biology; Volume 12; Issue 6; Pages: 806
Dyslipidemia is a significant risk factor for cardiovascular disease and stroke. Our recent findings showed that RCI-1502, a bioproduct derived from the muscle of the European S. pilchardus, has lipid-lowering effects in the liver and heart in high-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::651d999f21506c830090eb8d0a2d3347