Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Olafur A. Sveinsson"'
Autor:
Astros Th. Skuladottir, Vinicius Tragante, Gardar Sveinbjornsson, Hannes Helgason, Arni Sturluson, Anna Bjornsdottir, Palmi Jonsson, Vala Palmadottir, Olafur A. Sveinsson, Brynjar O. Jensson, Sigurjon A. Gudjonsson, Erna V. Ivarsdottir, Rosa S. Gisladottir, Arni F. Gunnarsson, G. Bragi Walters, Gudrun A. Jonsdottir, Thorgeir E. Thorgeirsson, Gyda Bjornsdottir, Hilma Holm, Daniel F. Gudbjartsson, Patrick Sulem, Hreinn Stefansson, Kari Stefansson
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-4 (2024)
Abstract Parkinson’s disease (PD) is a debilitating neurodegenerative disorder and its rising global incidence highlights the need for the identification of modifiable risk factors. In a gene-based burden test of rare variants (8647 PD cases and 77
Externí odkaz:
https://doaj.org/article/9aa8f9c144d343d0b195882dbbc8bdcb
Autor:
Astros Th. Skuladottir, Gyda Bjornsdottir, Egil Ferkingstad, Gudmundur Einarsson, Lilja Stefansdottir, Muhammad Sulaman Nawaz, Asmundur Oddsson, Thorunn A. Olafsdottir, Saedis Saevarsdottir, G. Bragi Walters, Sigurdur H. Magnusson, Anna Bjornsdottir, Olafur A. Sveinsson, Arnor Vikingsson, Thomas Folkmann Hansen, Rikke Louise Jacobsen, Christian Erikstrup, Michael Schwinn, Søren Brunak, Karina Banasik, Sisse Rye Ostrowski, Anders Troelsen, Cecilie Henkel, Ole Birger Pedersen, DBDS Genetic Consortium, Ingileif Jonsdottir, Daniel F. Gudbjartsson, Patrick Sulem, Thorgeir E. Thorgeirsson, Hreinn Stefansson, Kari Stefansson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
The underlying genetics of carpal tunnel syndrome is not well understood. Here, the authors perform a GWAS meta-analysis for carpal tunnel syndrome finding variants at 50 loci with connections to the extracellular matrix discovered through various fu
Externí odkaz:
https://doaj.org/article/569badaaffdf4538b77e6ebdcc046111
Autor:
Astros Th. Skuladottir, Gyda Bjornsdottir, Muhammad Sulaman Nawaz, Hannes Petersen, Solvi Rognvaldsson, Kristjan Helgi Swerford Moore, Pall I. Olafsson, Sigurður H. Magnusson, Anna Bjornsdottir, Olafur A. Sveinsson, Gudrun R. Sigurdardottir, Saedis Saevarsdottir, Erna V. Ivarsdottir, Lilja Stefansdottir, Bjarni Gunnarsson, Joseph B. Muhlestein, Kirk U. Knowlton, David A. Jones, Lincoln D. Nadauld, Annette M. Hartmann, Dan Rujescu, Michael Strupp, G. Bragi Walters, Thorgeir E. Thorgeirsson, Ingileif Jonsdottir, Hilma Holm, Gudmar Thorleifsson, Daniel F. Gudbjartsson, Patrick Sulem, Hreinn Stefansson, Kari Stefansson
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Astros Skuladottir et al. conducted a genome-wide association study on 48,072 vertigo cases and 894,541 controls from four populations with European ancestries. They identified six common variants associated with vertigo, thereby providing further in
Externí odkaz:
https://doaj.org/article/2f71e58c425346b081741b06b8a7001d
Autor:
Astros Th. Skuladottir, Gyda Bjornsdottir, Gudmar Thorleifsson, G. Bragi Walters, Muhammad Sulaman Nawaz, Kristjan Helgi Swerford Moore, Pall I. Olason, Thorgeir E. Thorgeirsson, Brynja Sigurpalsdottir, Gardar Sveinbjornsson, Hannes P. Eggertsson, Sigurdur H. Magnusson, Asmundur Oddsson, Anna Bjornsdottir, Arnor Vikingsson, Olafur A. Sveinsson, Maria G. Hrafnsdottir, Gudrun R. Sigurdardottir, Bjarni V. Halldorsson, Thomas Folkmann Hansen, Helene Paarup, Christian Erikstrup, Kaspar Nielsen, Mads Klokker, Mie Topholm Bruun, Erik Sorensen, Karina Banasik, Kristoffer S. Burgdorf, Ole Birger Pedersen, Henrik Ullum, Ingileif Jonsdottir, Hreinn Stefansson, Kari Stefansson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Bell’s palsy is the most common cause of unilateral facial paralysis and is defined as an idiopathic and acute inability to control movements of the facial muscles on the affected side. While the pathogenesis remains unknown, previous stud
Externí odkaz:
https://doaj.org/article/3d2fc42f3e4e427a80a49c09b7408bbb
Autor:
Guanglu Li, Shaojie Duan, International Headache Genetics Consortium (IHGC), Tao Zheng, Tiantian Zhu, Baoquan Qu, Lei Liu, Zunjing Liu, Verneri Anttila, Ville Artto, Andrea C Belin, Anna Bjornsdottir, Gyda Bjornsdottir, Dorret I Boomsma, Sigrid Børte, Mona A Chalmer, Daniel I Chasman, Bru Cormand, Ester Cuenca-Leon, George Davey-Smith, Irene de Boer, Martin Dichgans, Tonu Esko, Tobias Freilinger, Padhraig Gormley, Lyn R Griffiths, Eija Hämäläinen, Thomas F Hansen, Aster VE Harder, Heidi Hautakangas, Marjo Hiekkala, Maria G Hrafnsdottir, M. Arfan Ikram, Marjo-Riitta Järvelin, Risto Kajanne, Mikko Kallela, Jaakko Kaprio, Mari Kaunisto, Lisette JA Kogelman, Espen S Kristoffersen, Christian Kubisch, Mitja Kurki, Tobias Kurth, Lenore Launer, Terho Lehtimäki, Davor Lessel, Lannie Ligthart, Sigurdur H Magnusson, Rainer Malik, Bertram Müller-Myhsok, Carrie Northover, Dale R Nyholt, Jes Olesen, Aarno Palotie, Priit Palta, Linda M Pedersen, Nancy Pedersen, Matti Pirinen, Danielle Posthuma, Patricia Pozo-Rosich, Alice Pressman, Olli Raitakari, Caroline Ran, Gudrun R Sigurdardottir, Hreinn Stefansson, Kari Stefansson, Olafur A Sveinsson, Gisela M Terwindt, Thorgeir E Thorgeirsson, Arn MJM vanden Maagdenberg, Cornelia van Duijn, Maija Wessman, Bendik S Winsvold, John-Anker Zwart.
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundMigraine has an increased prevalence in several immune disorders, but genetic cause-effect relationships remain unclear. Mendelian randomization (MR) was used in this study to explore whether immune diseases are causally associated with mig
Externí odkaz:
https://doaj.org/article/a30f6c7b567e43149a0c5afd66373445
Publikováno v:
Laeknabladid. 108(11)
Transient Global Amnesia (TGA) is a benign syndrome characterized by sudden anterograde memory loss, that resolves spontaneously within 24 hours. TGA appears without other focal neurological symptoms. The aim of this study was to study TGA in the gre
Autor:
Thorgeir E. Thorgeirsson, Sigurdur H. Magnusson, Helene M. Paarup, Astros Skuladottir, Erik Elgaard Sørensen, Olafur A. Sveinsson, Gardar Sveinbjornsson, Brynja D. Sigurpalsdottir, Hreinn Stefansson, Christian Erikstrup, Muhammad Sulaman Nawaz, Gyda Bjornsdottir, Maria Gudlaug Hrafnsdottir, Gudrun R. Sigurdardottir, Pall I. Olason, G. Bragi Walters, Mie Topholm Bruun, Ingileif Jonsdottir, Thomas Hansen, Gudmar Thorleifsson, Bjarni V. Halldorsson, Kristoffer Sølvsten Burgdorf, Anna Bjornsdottir, Ole Birger Pedersen, Karina Banasik, Asmundur Oddsson, Henrik Ullum, Mads Klokker, Kari Stefansson, Kaspar René Nielsen, Arnor Vikingsson, Hannes P. Eggertsson, Kristjan H. S. Moore
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Skuladottir, A T, Bjornsdottir, G, Thorleifsson, G, Walters, G B, Nawaz, M S, Moore, K H S, Olason, P I, Thorgeirsson, T E, Sigurpalsdottir, B, Sveinbjornsson, G, Eggertsson, H P, Magnusson, S H, Oddsson, A, Bjornsdottir, A, Vikingsson, A, Sveinsson, O A, Hrafnsdottir, M G, Sigurdardottir, G R, Halldorsson, B V, Hansen, T F, Paarup, H, Erikstrup, C, Nielsen, K, Klokker, M, Bruun, M T, Sorensen, E, Banasik, K, Burgdorf, K S, Pedersen, O B, Ullum, H, Jonsdottir, I, Stefansson, H & Stefansson, K 2021, ' A meta-analysis uncovers the first sequence variant conferring risk of Bell’s palsy ', Scientific Reports, vol. 11, no. 1, 4188 . https://doi.org/10.1038/s41598-021-82736-w
Skuladottir, A T, Bjornsdottir, G, Thorleifsson, G, Walters, G B, Nawaz, M S, Moore, K H S, Olason, P I, Thorgeirsson, T E, Sigurpalsdottir, B, Sveinbjornsson, G, Eggertsson, H P, Magnusson, S H, Oddsson, A, Bjornsdottir, A, Vikingsson, A, Sveinsson, O A, Hrafnsdottir, M G, Sigurdardottir, G R, Halldorsson, B V, Hansen, T F, Paarup, H, Erikstrup, C, Nielsen, K, Klokker, M, Bruun, M T, Sorensen, E, Banasik, K, Burgdorf, K S, Pedersen, O B, Ullum, H, Jonsdottir, I, Stefansson, H & Stefansson, K 2021, ' A meta-analysis uncovers the first sequence variant conferring risk of Bell’s palsy ', Scientific Reports, vol. 11, 4188 . https://doi.org/10.1038/s41598-021-82736-w
Skuladottir, A T, Bjornsdottir, G, Thorleifsson, G, Walters, G B, Nawaz, M S, Moore, K H S, Olason, P I, Thorgeirsson, T E, Sigurpalsdottir, B, Sveinbjornsson, G, Eggertsson, H P, Magnusson, S H, Oddsson, A, Bjornsdottir, A, Vikingsson, A, Sveinsson, O A, Hrafnsdottir, M G, Sigurdardottir, G R, Halldorsson, B V, Hansen, T F, Paarup, H, Erikstrup, C, Nielsen, K, Klokker, M, Bruun, M T, Sørensen, E, Banasik, K, Burgdorf, K S, Pedersen, O B, Ullum, H, Jonsdottir, I, Stefansson, H & Stefansson, K 2021, ' A meta-analysis uncovers the first sequence variant conferring risk of Bell’s palsy ', Scientific Reports, vol. 11, no. 1, 4188 . https://doi.org/10.1038/s41598-021-82736-w
Scientific Reports
Skuladottir, A T, Bjornsdottir, G, Thorleifsson, G, Walters, G B, Nawaz, M S, Moore, K H S, Olason, P I, Thorgeirsson, T E, Sigurpalsdottir, B, Sveinbjornsson, G, Eggertsson, H P, Magnusson, S H, Oddsson, A, Bjornsdottir, A, Vikingsson, A, Sveinsson, O A, Hrafnsdottir, M G, Sigurdardottir, G R, Halldorsson, B V, Hansen, T F, Paarup, H, Erikstrup, C, Nielsen, K, Klokker, M, Bruun, M T, Sorensen, E, Banasik, K, Burgdorf, K S, Pedersen, O B, Ullum, H, Jonsdottir, I, Stefansson, H & Stefansson, K 2021, ' A meta-analysis uncovers the first sequence variant conferring risk of Bell’s palsy ', Scientific Reports, vol. 11, no. 1, 4188 . https://doi.org/10.1038/s41598-021-82736-w
Skuladottir, A T, Bjornsdottir, G, Thorleifsson, G, Walters, G B, Nawaz, M S, Moore, K H S, Olason, P I, Thorgeirsson, T E, Sigurpalsdottir, B, Sveinbjornsson, G, Eggertsson, H P, Magnusson, S H, Oddsson, A, Bjornsdottir, A, Vikingsson, A, Sveinsson, O A, Hrafnsdottir, M G, Sigurdardottir, G R, Halldorsson, B V, Hansen, T F, Paarup, H, Erikstrup, C, Nielsen, K, Klokker, M, Bruun, M T, Sorensen, E, Banasik, K, Burgdorf, K S, Pedersen, O B, Ullum, H, Jonsdottir, I, Stefansson, H & Stefansson, K 2021, ' A meta-analysis uncovers the first sequence variant conferring risk of Bell’s palsy ', Scientific Reports, vol. 11, 4188 . https://doi.org/10.1038/s41598-021-82736-w
Skuladottir, A T, Bjornsdottir, G, Thorleifsson, G, Walters, G B, Nawaz, M S, Moore, K H S, Olason, P I, Thorgeirsson, T E, Sigurpalsdottir, B, Sveinbjornsson, G, Eggertsson, H P, Magnusson, S H, Oddsson, A, Bjornsdottir, A, Vikingsson, A, Sveinsson, O A, Hrafnsdottir, M G, Sigurdardottir, G R, Halldorsson, B V, Hansen, T F, Paarup, H, Erikstrup, C, Nielsen, K, Klokker, M, Bruun, M T, Sørensen, E, Banasik, K, Burgdorf, K S, Pedersen, O B, Ullum, H, Jonsdottir, I, Stefansson, H & Stefansson, K 2021, ' A meta-analysis uncovers the first sequence variant conferring risk of Bell’s palsy ', Scientific Reports, vol. 11, no. 1, 4188 . https://doi.org/10.1038/s41598-021-82736-w
Bell’s palsy is the most common cause of unilateral facial paralysis and is defined as an idiopathic and acute inability to control movements of the facial muscles on the affected side. While the pathogenesis remains unknown, previous studies have
Publikováno v:
Laeknabladid. 108(2)
Cerebral venous sinus thrombosis (CSVT) is the cause of 0.5%-1% of all strokes. CSVT can cause haemorrhage, cerebral infarction and increased intracranial pressure. Due to a variety of symptoms, CSVT can be difficult to diagnose. The purpose of this
Autor:
Tobias Kurth, Nadine Pelzer, Hautakangas H, Artto, O T Raitakari, Julie E. Buring, Penninx Bwjh., Christian Erikstrup, Mikko Kallela, Matti Pirinen, Christian Benner, Daniel I. Chasman, Kristian Hveem, Kristoffersen Es, Torben Hansen, Olafur A. Sveinsson, Mika Kähönen, van den Maagdenberg Amjm., Mona Ameri Chalmer, Aarno Palotie, Elisabeth Widen, Thorgeir E. Thorgeirsson, Hreinn Stefansson, Lighart L, Paul M. Ridker, de Boer I, Gisela M. Terwindt, Garbrielsen Me, Jouke J. Hottenga, Kogelman Lja., Arpo Aromaa, Bendik S. Winsvold, Dale R. Nyholt, Ikram Ma, van Dijk Kw, Harder Ave, Martin Dichgans, Rainer Malik, Mohsen Ghanbari, Marianne Bakke Johnsen, Marjo-Ritta Jarvelin, Samuli Ripatti, Paavo Häppölä, Gyda Bjornsdottir, Martti Färkkilä, Anne Heidi Skogholt, Terho Lehtimäki, Sanni Ruotsalainen, Frits R. Rosendaal, Gudrun R. Sigurdardottir, Headache Ha, Gormley P, Kari Stefansson, J.A. Zwart, Oluf Pedersen, Raymond Noordam, Ben Michael Brumpton, Laurent F. Thomas, Karina Banasik, M.G. Hrafnsdottir, Lisanne S. Vijfhuizen, Sølvsten Burgdorf K, Jes Olesen, Sigurdur H. Magnusson, T. Freilinger, Kristen Hagen, Andrea Carmine Belin, Dorret I. Boomsma, Henrik Ullum, Maija Wessman, Ran C, Anna Bjornsdottir
Migraine affects over a billion individuals worldwide but its genetic underpinning remains largely unknown. This genome-wide association study (GWAS) of 102,084 migraine cases and 771,257 controls identified 123 loci of which 86 are novel. The loci p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e64e0da2e2c833014db37279373369e
https://doi.org/10.1101/2021.01.20.21249647
https://doi.org/10.1101/2021.01.20.21249647
Autor:
Ingileif Jonsdottir, Saedis Saevarsdottir, Lincoln Nadauld, Kirk U. Knowlton, Dan Rujescu, Kristjan H. S. Moore, Patrick Sulem, Gudmar Thorleifsson, Annette M. Hartmann, Michael Strupp, Hannes Petersen, Astros Skuladottir, Pall I. Olafsson, Lilja Stefansdottir, Olafur A. Sveinsson, Muhammad Sulaman Nawaz, Joseph B. Muhlestein, Solvi Rognvaldsson, Kari Stefansson, David A. Jones, Hreinn Stefansson, G. Bragi Walters, Thorgeir E. Thorgeirsson, Erna V. Ivarsdottir, Bjarni Gunnarsson, Sigurður H. Magnusson, Daniel F. Gudbjartsson, Hilma Holm, Gyda Bjornsdottir, Gudrun R. Sigurdardottir, Anna Bjornsdottir
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Vertigo is the leading symptom of vestibular disorders and a major risk factor for falls. In a genome-wide association study of vertigo (Ncases = 48,072, Ncontrols = 894,541), we uncovered an association with six common sequence variants in individua