Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Olaf Oberschmidt"'
Autor:
Stephan Kloess, Alessa Ede Valverde da Silva, Olaf Oberschmidt, Tanja Gardlowski, Nadine Matthies, Maulik Vyas, Lubomir Arseniev, Michael Heuser, Elke Pogge von Strandmann, Ulrike Köhl
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/dd9a011b34be4f2cbb553cd2cebd7415
Autor:
Stephan Kloess, Alessa Ede Valverde da Silva, Olaf Oberschmidt, Tanja Gardlowski, Nadine Matthies, Maulik Vyas, Lubomir Arseniev, Michael Heuser, Elke Pogge von Strandmann, Ulrike Köhl
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Natural killer cells (NK) are essential for the elimination of resistant acute myeloid and acute lymphoblastic leukemia (AML and ALL) cells. NK cell-based immunotherapies have already successfully entered for clinical trials, but limitations due to i
Externí odkaz:
https://doaj.org/article/87d47e2d6c31487f8bd62f33d2409993
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Primary human natural killer (NK) cells recognize and subsequently eliminate virus infected cells, tumor cells, or other aberrant cells. However, cancer cells are able to develop tumor immune escape mechanisms to undermine this immune control. To ove
Externí odkaz:
https://doaj.org/article/100abd1ef9fa411aacd3608f303942a4
Autor:
Volker Huppert, Olaf Oberschmidt, Axel Schambach, Krasimira Aleksandrova, Tanja Gardlowski, Lubomir Arseniev, Joerg Kessler, Nadine Matthies, Michael A. Morgan, Ulrike Koehl, Stephan Kloess
Publikováno v:
Human Gene Therapy Methods
In cellular immunotherapies, natural killer (NK) cells often demonstrate potent antitumor effects in high-risk cancer patients. But Good Manufacturing Practice (GMP)-compliant manufacturing of clinical-grade NK cells in high numbers for patient treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdf6d419fd240dfbfa3c1a950609be0
http://europepmc.org/articles/PMC6590729
http://europepmc.org/articles/PMC6590729
Autor:
Nadine Matthies, Christine Neudoerfl, Xuan-Khang Vu, Stephan Kloess, Axel Schambach, Christine S. Falk, Tanja Gardlowski, Johann Meyer, Julia Dahlke, Michael A. Morgan, Martin Sauer, Olaf Oberschmidt, Ulrike Koehl, Arnold Kloos, Michael Heuser
Publikováno v:
Human Gene Therapy. 30:381-401
The introduction of chimeric antigen receptors (CARs) to augment the anticancer activity of immune cells represents one of the major clinical advances in recent years. This work demonstrates that sorted CAR natural killer (NK) cells have improved ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba396fd8facadc354b53c029118e44d
https://doi.org/10.1089/hum.2018.247
https://doi.org/10.1089/hum.2018.247
Autor:
Ulrike Koehl, Nadine Matthies, Axel Schambach, Stephan Klöß, Julia Dahlke, Michael A. Morgan, Volker Huppert, Markus Granzin, Stephanie Soltenborn, Lubomir Arseniev, Tanja Gardlowski, Olaf Oberschmidt
Publikováno v:
Human Gene Therapy. 28:897-913
The administration of ex vivo expanded natural killer (NK) cells as potential antitumor effector cells appears to be suitable for effector cell-based immunotherapies in high-risk cancer patients. However, good manufacturing practice (GMP)-compliant m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cad00bae6bf177cf436a89f1e3d1c33
https://doi.org/10.1089/hum.2017.157
https://doi.org/10.1089/hum.2017.157
Autor:
Stephan Kloess, Maulik Vyas, Lubomir Arseniev, Olaf Oberschmidt, Michael Heuser, Nadine Matthies, Alessa Ede Valverde da Silva, Tanja Gardlowski, Ulrike Köhl, Elke Pogge von Strandmann
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Natural killer cells (NK) are essential for the elimination of resistant acute myeloid and acute lymphoblastic leukemia (AML and ALL) cells. NK cell-based immunotherapies have already successfully entered for clinical trials, but limitations due to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7682fd8e896c90a3f75e1df008dd0138
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Frontiers in Immunology
Primary human natural killer (NK) cells recognize and subsequently eliminate virus infected cells, tumor cells, or other aberrant cells. However, cancer cells are able to develop tumor immune escape mechanisms to undermine this immune control. To ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af0b697aa837084c82a243fa79692ca
Autor:
Hartmut M. Hanauske-Abel, Victor J. Chen, Doreen Ma, Michael Lahn, Heike Pospisil, Ulrike Eismann, Axel-Rainer Hanauske, Olaf Oberschmidt, J. Blatter
Publikováno v:
Investigational New Drugs. 26:215-222
Purpose: Enzastaurin (LY317615) is a novel serine/threonine kinase inhibitor, targeting Protein Kinase C-beta (PKC-β), and PI3K/AKT pathways to inhibit angiogenesis and tumor cell proliferation. The aims of this study were to determine whether Enzas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed361a79f7e04910fe4ec6ea34bcc0e
https://doi.org/10.1007/s10637-007-9095-y
https://doi.org/10.1007/s10637-007-9095-y
Autor:
Doreen Ma, Paolo Paoletti, Steve Hoffmann, Olaf Oberschmidt, Heike Pospisil, Clet Niyikiza, Hartmut M. Hanauske-Abel, Victor J. Chen, Axel-Rainer Hanauske, Ulrike Eismann
Publikováno v:
Investigational New Drugs. 25:417-423
mRNA expression of genes involved in the mechanism of action of pemetrexed was correlated with in vitro chemosensitivity of freshly explanted human tumor specimens.Chemosensitivity to pemetrexed was studied in soft-agar. Multiplex rtPCR experiments f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d143c61687cd6d6d7611ce26eaf7e6be
https://doi.org/10.1007/s10637-007-9060-9
https://doi.org/10.1007/s10637-007-9060-9