Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Olaf J C Hellwinkel"'
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1649 (2024)
Novel biomarkers and therapeutic strategies for glioblastoma, the most common malignant brain tumor with an extremely unfavorable prognosis, are urgently needed. Recent studies revealed a significant upregulation of the protein zonulin in glioblastom
Externí odkaz:
https://doaj.org/article/2ed0781664114a28a9096321cdc0fc4f
Autor:
Daniel A. Wenzel, Constanze Schultheiss, Vasyl Druchkiv, Olaf J. C. Hellwinkel, Martin S. Spitzer, Maximilian Schultheiss, Maria Casagrande, Nils Alexander Steinhorst
Publikováno v:
BMC Ophthalmology, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Cataract surgery induces corneal endothelial cell loss (ECL). This study investigates the relationship between bottle height (BH) and ECL induced due to irrigation and aspiration (I/A) in cataract surgery and quantifies protective
Externí odkaz:
https://doaj.org/article/c5d2a9e20e95496bbf7193b8d6ed3bd8
Autor:
Tristan Daehn, Andreas Schneider, Johannes Knobloch, Olaf J. C. Hellwinkel, Martin Stephan Spitzer, Robert Kromer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
Abstract In this study, we examined the rate of contamination of multi-dose ophthalmic solutions in the operating theatre and the underlying risk for infection by examining the microbiological load on the tips of the dispenser bottles. A total of 245
Externí odkaz:
https://doaj.org/article/7d453ccf99604379a94d9bca45a274b8
Autor:
Filip Filev, Mathias Stein, Maximilian Schultheiss, Antonia D. E. Fitzek, Jana Feuerstake, Oliver Engel, Olaf J. C. Hellwinkel
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology.
Background The quality of the endothelial cell layer is a major criterion for the approval of organ-cultured human donor-corneas for transplantation. We wanted to compare the predictive capacities of initial endothelial density and endothelium cell m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::054e091389ebfad9d18d9b92c9c20195
https://doi.org/10.1007/s00417-023-06079-0
https://doi.org/10.1007/s00417-023-06079-0
Autor:
Filip Filev, Ismini Koulouri, Sibylle Altenähr, Jana Feuerstacke, Olaf J C Hellwinkel, Martin S. Spitzer, Stefan Fritz
Publikováno v:
Cell and Tissue Banking. 21:507-521
In this experimental study we used for the first time Tiprotec® as a solution for corneal preservation and cold storage. We compared the resultant endothelial cell morphology and viability with this obtained after preservation of the ex-vivo corneas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3fa3275ce054aaa1909c401f5b9190
https://doi.org/10.1007/s10561-020-09838-z
https://doi.org/10.1007/s10561-020-09838-z
Autor:
Olaf J C Hellwinkel, Berthold Seitz, Katja Rosenbaum, Sibylle Katharina Scholtz, Thomas Wegner, Frank Krogmann, Gerd Geerling, Daniel Kampik, Gerd U. Auffarth, Philip Maier
Publikováno v:
Klinische Monatsblatter fur Augenheilkunde. 238(6)
Ever since the first successful keratoplasty in 1905, there has been a need to store corneas for transplantation. R. Townley Paton founded the first eye bank in New York in 1944. With Helen Keller's call in 1925 for LIONS to "constitute themselves Kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcaca6b8cdaaafce202c766aabc58c01
https://pubmed.ncbi.nlm.nih.gov/33733449
https://pubmed.ncbi.nlm.nih.gov/33733449
Autor:
Olaf J C Hellwinkel, Henning Thomasen, Gerd Geerling, Patrick R Merz, Berthold Seitz, Johannes Menzel-Severing, Sabine Salla, Constantin E. Uhlig, Sebastian Thaler, Daniel Kampik, Céline Trigaux, Melissa Apel, Florian Raber, Sigrid Roters, Philip Maier, Ilka Wittmershaus, Norbert Schrage, Bernhard Nölle, Theofilos Tourtas, Jan Schroeter, Andrea Gareiss-Lok
Publikováno v:
Current Eye Research
Introduction Since the beginning of the COVID-19 pandemic there has been some debate regarding the risk of transmission through tissue transplantation and tissue banking processes. Aim of the study To analyze the changes that SARS-CoV-2 has caused re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81fdbe5fbcf07a173709319092e8738
https://pubmed.ncbi.nlm.nih.gov/33016144
https://pubmed.ncbi.nlm.nih.gov/33016144
Autor:
Olaf J C Hellwinkel, Robert Kromer, Johannes K.-M. Knobloch, Tristan Daehn, Martin S. Spitzer, Andreas Schneider
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
In this study, we examined the rate of contamination of multi-dose ophthalmic solutions in the operating theatre and the underlying risk for infection by examining the microbiological load on the tips of the dispenser bottles. A total of 245 samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6dbecbf5a23ee9c344d255f334da77e
https://pubmed.ncbi.nlm.nih.gov/34645913
https://pubmed.ncbi.nlm.nih.gov/34645913
Autor:
Nils Alexander Steinhorst, Jana Feuerstacke, Filip Filev, Eileen Bigdon, Birgit Wulff, Carolin Schröder, Olaf J C Hellwinkel, Stephan J. Linke, A Kammal
Publikováno v:
Cornea. 37:957-963
Purpose To compare whole eye enucleation and corneoscleral disc (CD) excision as donor cornea harvesting techniques for possible effects on corneal cultivation and the clinical outcome of the corneal grafts after transplantation in 2929 cases. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f960ec7c278e081f9a50127406efe7c3
https://doi.org/10.1097/ico.0000000000001622
https://doi.org/10.1097/ico.0000000000001622
Publikováno v:
Seminars in Ophthalmology. 33:338-344
PURPOSE The purpose of this study is to analyze the impact of death causes and documented donor diseases on initial endothelial cell counts (after retrieval) and the development of corneal graft endothelia during organ culture. METHODS The retrospect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b527995361b05f8874fd71d76eff04e5
https://doi.org/10.1080/08820538.2016.1238100
https://doi.org/10.1080/08820538.2016.1238100