Spontaneous Epileptic Recordings from hiPSC-Derived Cortical Neurons Cultured with a Human Epileptic Brain Biopsy on a Multi Electrode Array

Autor: Michel H. Y. Hu, Jean-Philippe Frimat, Kim Rijkers, Olaf E. M. G. Schijns, Arn M. J. M. van den Maagdenberg, Jim T. A. Dings, Regina Luttge, Govert Hoogland

Publikováno v: Applied Sciences, Vol 13, Iss 3, p 1432 (2023)

A growing societal awareness is calling upon scientists to reconsider the use of animals in research, which stimulates the development of translational in vitro models. The physiological and architectural interactions between different cell types wit

Externí odkaz: https://doaj.org/article/326a75b1c75f40a1b234e2fd548a4c1e

Combining Gamma With Alpha and Beta Power Modulation for Enhanced Cortical Mapping in Patients With Focal Epilepsy

Autor: Mario E. Archila-Meléndez, Giancarlo Valente, Erik D. Gommer, João M. Correia, Sanne ten Oever, Judith C. Peters, Joel Reithler, Marc P. H. Hendriks, William Cornejo Ochoa, Olaf E. M. G. Schijns, Jim T. A. Dings, Danny M. W. Hilkman, Rob P. W. Rouhl, Bernadette M. Jansma, Vivianne H. J. M. van Kranen-Mastenbroek, Mark J. Roberts

Publikováno v: Frontiers in Human Neuroscience, Vol 14 (2020)

About one third of patients with epilepsy have seizures refractory to the medical treatment. Electrical stimulation mapping (ESM) is the gold standard for the identification of “eloquent” areas prior to resection of epileptogenic tissue. However,

Externí odkaz: https://doaj.org/article/3eaac8d166c34642974ff47af5fb955d

Neurocognition in adults with intracranial tumors

Autor: Charlotte Sleurs, Catharina M. L. Zegers, Inge Compter, Jeanette Dijkstra, Monique H. M. E. Anten, Alida A. Postma, Olaf E. M. G. Schijns, Ann Hoeben, Margriet M. Sitskoorn, Wouter De Baene, Laurien De Roeck, Stefan Sunaert, Wouter Van Elmpt, Maarten Lambrecht, Daniëlle B. P. Eekers

Publikováno v: Journal of Neuro-Oncology, 160(3), 619-629. Kluwer Academic Publishers
Journal of Neuro-Oncology, 160(3), 619-629. Springer, Cham

Objective As preservation of cognitive functioning increasingly becomes important in the light of ameliorated survival after intracranial tumor treatments, identification of eloquent brain areas would enable optimization of these treatments. Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08df367bd0b417da68409ac4b4ed64e
https://doi.org/10.1007/s11060-022-04181-7

Myasthenia gravis after glioblastoma resection: paraneoplastic syndrome or coincidence? A unique case report and review of the literature

Autor: Martinus P.G. Broen, J. G. J. Hoeijmakers, Ann Hoeben, Inge Compter, Olaf E. M. G. Schijns, T. A. M. Bouwens van der Vlis, R. J. Slegers, Alida A. Postma, Linda Ackermans, Jan Beckervordersandforth

Publikováno v: Acta Neurochirurgica. 164(2):423-427

Paraneoplastic neurological syndromes (PNS) can manifest with every type of malignancy. A well-known syndrome is myasthenia gravis (MG) in combination with thymomas. No association between primary brain tumors and neuromuscular disorders has been des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61fe6220303031d3836fb4060fd9173
https://doi.org/10.1007/s00701-021-05035-3

Basal protein synthesis rates differ between vastus lateralis and rectus abdominis muscle

Autor: Olaf E. M. G. Schijns, Astrid M. H. Horstman, Luc J. C. van Loon, Steven W.M. Olde Damink, Joost F Ter Woorst, Joey S J Smeets, David P.J. van Dijk, Astrid G M van Boxtel

Publikováno v: Journal of cachexia, sarcopenia and muscle, 12(3), 769-778. Wiley
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 3, Pp 769-778 (2021)
Journal of Cachexia, Sarcopenia and Muscle

Background In vivo muscle protein synthesis rates are typically assessed by measuring the incorporation rate of stable isotope labelled amino acids in skeletal muscle tissue collected from vastus lateralis muscle. It remains to be established whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082df6c305b6b4c39333a09f618f2a80
https://doi.org/10.1002/jcsm.12701